Jet confinement by magneto-torsional oscillations

Many quasars and active galactic nuclei (AGN) appear in radio, optical, and X-ray maps, as a bright nuclear sources from which emerge single or double long, thin jets. When observed with high angular resolution these jets show structure with bright knots separated by relatively dark regions. Nonthermal nature of a jet radiation is well explained as the synchrotron radiation of the relativistic electrons in an ordered magnetic field. We consider magnetic collimation, connected with torsional oscillations of a cylinder with elongated magnetic field, and periodically distributed initial rotation around the cylinder axis. The stabilizing azimuthal magnetic field is created here by torsional oscillations, where charge separation is not necessary. Approximate simplified model is developed. Ordinary differential equation is derived, and solved numerically, what gives a possibility to estimate quantitatively the range of parameters where jets may be stabilized by torsional oscillations.Comment: accepted for publication in Astrophysics and Space Scienc

Coral diversity and the severity of disease outbreaks: a cross-regional comparison of Acropora White Syndrome in a species-rich region (American Samoa) with a species-poor region (Northwestern Hawaiian Islands)

The dynamics of the coral disease, Acropora white syndrome (AWS), was directly compared on reefs in the species-poor region of the Northwestern Hawaiian Islands (NWHI) and the species-rich region of American Samoa (AS) with results suggesting that biodiversity, which can affect the abundance of susceptible hosts, is important in influencing the impacts of coral disease outbreaks. The diversity-disease hypothesis predicts that decreased host species diversity should result in increased disease severity of specialist pathogens. We found that AWS was more prevalent and had a higher incidence within the NWHI as compared to AS. Individual Acropora colonies affected by AWS showed high mortality in both regions, but case fatality rate and disease severity was higher in the NWHI. The site within the NWHI had a monospecific stand of A. cytherea; a species that is highly susceptible to AWS. Once AWS entered the site, it spread easily amongst the abundant susceptible hosts. The site within AS contained numerous Acropora species, which differed in their apparent susceptibility to infection and disease severity, which in turn reduced disease spread. Manipulative studies showed AWS was transmissible through direct contact in three Acropora species. These results will help managers predict and respond to disease outbreaks

Peer review in academic publishing: challenges in achieving the gold standard

This editorial describes some of the current and emerging challenges in peer review for the academic publishing system. Peer review is a fundamental element of academic research and publishing, with a firm reliance on the global scholarly community to perform gatekeeping and filtering processes in pursuing high-quality and high-value scholarly publications: the “gold standard” in academic publishing. We begin with examples of several contemporary challenges the peer review system poses, including impartiality and bias, academic reward structures, fake peer reviews, and reviewer fatigue. To further understand these challenges, we then provide a brief history of the evolution of the peer review system, focusing on the traditional forms of pre-publication peer review so familiar to the communication of scholarly work. Against this backdrop, we consider the benefits of peer review that span the continuum of the academic community – from authors to reviewers to journals and research communities. But many traditional forms of peer review are being challenged by new and innovative processes, systems and platforms. Finally, we look at how others have re-envisioned the peer review process during this phase of rapid evolution in journal publishing, with a strong call for quality and integrity in writing peer reviews. We conclude by suggesting ways forward for embedding sustainability, equity, and respect within the peer review process as an active force for advancing scholarship. Practitioner Notes 1. Contemporary peer review is a ubiquitous and institutionalised process in the global communication of scholarly works. 2. Innovation in new social platforms, technical systems, communication methods, and changing academic environments are challenging the traditional forms of peer review. 3. Despite criticisms of the scholarly peer review process-the role of biases, the “publish or perish” culture of academia, fraudulent peer review, peer reviewer fatigue, the Reviewer Number 2 trope, and the question of quality assurance-there is still value. 4. Authors, reviewers, journal editors and research communities all benefit from high-quality peer review. 5. Research communities should champion high-quality peer review as an active force for advancing scholarship

Casimir scaling of SU(3) static potentials

Potentials between static colour sources in eight different representations are computed in four dimensional SU(3) gauge theory. The simulations have been performed with the Wilson action on anisotropic lattices where the renormalised anisotropies have been determined non-perturbatively. After an extrapolation to the continuum limit we are able to exclude any violations of the Casimir scaling hypothesis that exceed 5% for source separations of up to 1 fm.Comment: 12 pages, 10 figures, RevTeX, v2: 1 reference added, more explanation about advantages of anisotrop

The (LATTICE) QCD Potential and Running Coupling: How to Accurately Interpolate between Multi-Loop QCD and the String Picture

We present a simple parameterization of a running coupling constant, defined via the static potential, that interpolates between 2-loop QCD in the UV and the string prediction in the IR. Besides the usual \Lam-parameter and the string tension, the coupling depends on one dimensionless parameter, determining how fast the crossover from UV to IR behavior occurs (in principle we know how to take into account any number of loops by adding more parameters). Using a new Ansatz for the LATTICE potential in terms of the continuum coupling, we can fit quenched and unquenched Monte Carlo results for the potential down to ONE lattice spacing, and at the same time extract the running coupling to high precision. We compare our Ansatz with 1-loop results for the lattice potential, and use the coupling from our fits to quantitatively check the accuracy of 2-loop evolution, compare with the Lepage-Mackenzie estimate of the coupling extracted from the plaquette, and determine Sommer's scale $r_0$ much more accurately than previously possible. For pure SU(3) we find that the coupling scales on the percent level for $\beta\geq 6$.Comment: 47 pages, incl. 4 figures in LaTeX [Added remarks on correlated vs. uncorrelated fits in sect. 4; corrected misprints; updated references.

Differential regulation of effector- and central-memory responses to Toxoplasma gondii infection by IL-12 revealed by tracking of Tgd057-specific CD8+ T cells

10.1371/journal.ppat.1000815PLoS Pathogens6

Direct Visualization of Antigen-specific CD8+T Cells during the Primary Immune Response to Epstein-Barr Virus In Vivo

Primary infection with virus can stimulate a vigorous cytotoxic T cell response. The magnitude of the antigen-specific component versus the bystander component of a primary T cell response remains controversial. In this study, we have used tetrameric major histocompatibility complex–peptide complexes to directly visualize antigen-specific cluster of differentration (CD)8+ T cells during the primary immune response to Epstein-Barr virus (EBV) infection in humans. We show that massive expansion of activated, antigen-specific T cells occurs during the primary response to this virus. In one individual, T cells specific for a single EBV epitope comprised 44% of the total CD8+ T cells within peripheral blood. The majority of the antigen-specific cells had an activated/memory phenotype, with expression of human histocompatibility leukocyte antigen (HLA) DR, CD38, and CD45RO, downregulation of CD62 leukocyte (CD62L), and low levels of expression of CD45RA. After recovery from AIM, the frequency of antigen-specific T cells fell in most donors studied, although populations of antigen-specific cells continued to be easily detectable for at least 3 yr

ADM formulation of the General Relativity

Se realiza el estudio del formalismo ADM para la Teoría de la Relatividad General mediante el método de las foliaciones en las superficies de Cauchy. Se presenta explícitamente el desarrollo matemático que conduce, finalmente, a la formulación hamiltoniana de la Relatividad General.The study of the ADM formalism for the General Relativity Theory through the foliation methods on the Cauchy surfacesis is realized. The mathematical development that leads to the Hamiltonian formulation of General Relativity is presented explicitly

Cosmogenic nuclides constrain surface fluctuations of an East Antarctic outlet glacier since the Pliocene

Understanding past changes in the Antarctic ice sheets provides insight into how they might respond to future climate warming. During the Pliocene and Pleistocene, geological data show that the East Antarctic Ice Sheet responded to glacial and interglacial cycles by remaining relatively stable in its interior, but oscillating at its marine-based margin. It is currently not clear how outlet glaciers, which connect the ice sheet interior to its margin, responded to these orbitally-paced climate cycles. Here we report new ice surface constraints from Skelton Glacier, an outlet of the East Antarctic ice sheet, which drains into the Ross Ice Shelf. Our multiple-isotope (10Be and 26Al) cosmogenic nuclide data indicate that currently ice-free areas adjacent to the glacier underwent substantial periods of exposure and ice cover in the past. We use an exposure-burial model driven by orbitally-paced glacial–interglacial cycles to determine the probable ice surface history implied by our data. This analysis shows that: 1) the glacier surface has likely fluctuated since at least the Pliocene; 2) the ice surface was >200 m higher than today during glacial periods, and the glacier has been thicker than present for ∼75–90% of each glacial–interglacial cycle; and 3) ice cover at higher elevations possibly occurred for a relatively shorter time per Pliocene cycle than Pleistocene cycle. Our multiple-nuclide approach demonstrates the magnitude of ice surface fluctuations during the Pliocene and Pleistocene that are linked to marine-based ice margin variability