Museus & Pessoas: Isabel Victor

Isabel Victor é desde Abril de 2017 directora do Museu Sporting, em Lisboa. Alia o profissionalismo com a paixão pelo trabalho em museus, o gosto por aprender, fazer e discutir, e a inquietude da curiosidade. Há pouco mais de um ano na direcção do museu, fomos até ao Estádio de Alvalade, onde está instalado o museu, para conhecer melhor o percurso de Isabel Victor, as suas motivações e as ideias que traz para o Museu Sporting e para este novo ciclo profissional.UID/HIS/00057/2013 (POCI-01-0145-FEDER-007702

Diffraction bar-codes as high capacity optical microtags for chemical and biological applications

The rapid advances in high throughput screening, combinatorial chemistry, genomic and proteomic sciences have stimulated dramatic development of new encoding strategies for bead-based assays. Several optical encoding methods are currently used in these applications, including fluorescence, Raman and magnetic tagging on microbeads. Here we describe a new method for encoding small beads which allows for non-contact reading and offer potentially millions of distinguishable tags. The tagging technique is based on fabricating a nano-structured pattern on the surface of the particle, which is only a few microns in size, read by detecting the spatial distribution of laser light diffracted by the tag. In the simplest implementation, the pattern is no more than a miniature diffraction grating, where information is coded in the pitch or spatial dimensions of the grating, read by detecting the angle of the diffracted orders. A huge increase in capacity has been achieved by using a number of superimposed gratings with different pitch and by employing two dimensional gratings. Distinguishing of tens of thousands of tags has been demonstrated on a chromium-on-glass chip library of 50 µm long tags. The technique has also been proved with biologically compatible gratings manufactured on metal nanoparticle doped SU8 photo-polymer

Superimposed Nanostructured Diffraction Gratings as High Capacity Barcodes for Biological and Chemical Applications

We describe a new non-contact high capacity optical tagging technique for bead based assays, based on the use of nanostructured barcodes. The tags are generated from a number of superimposed diffraction gratings. With one-dimensional diffraction, capacity for up to 68,000 distinguishable tags has been demonstrated, with a theoretical capacity of up to 109 tags. Extension into two dimensions increases this theoretical limit to 1021 tags