35 research outputs found

    Analysis of the X(1835) and related baryonium states with Bethe-Salpeter equation

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    In this article, we study the mass spectrum of the baryon-antibaryon bound states ppˉp\bar{p}, ΣΣˉ\Sigma\bar{\Sigma}, ΞΞˉ\Xi\bar{\Xi}, ΛΛˉ\Lambda\bar{\Lambda}, pNˉ(1440)p\bar{N}(1440), ΣΣˉ(1660)\Sigma\bar{\Sigma}(1660), ΞΞˉ′\Xi\bar{\Xi}^\prime and ΛΛˉ(1600)\Lambda\bar{\Lambda}(1600) with the Bethe-Salpeter equation. The numerical results indicate that the ppˉp\bar{p}, ΣΣˉ\Sigma\bar{\Sigma}, ΞΞˉ\Xi\bar{\Xi}, pNˉ(1440)p\bar{N}(1440), ΣΣˉ(1660)\Sigma\bar{\Sigma}(1660), ΞΞˉ′\Xi\bar{\Xi}^\prime bound states maybe exist, and the new resonances X(1835) and X(2370) can be tentatively identified as the ppˉp\bar{p} and pNˉ(1440)p\bar{N}(1440) (or N(1400)pˉN(1400)\bar{p}) bound states respectively with some gluon constituents, and the new resonance X(2120) may be a pseudoscalar glueball. On the other hand, the Regge trajectory favors identifying the X(1835), X(2120) and X(2370) as the excited η′(958)\eta^\prime(958) mesons with the radial quantum numbers n=3n=3, 4 and 5, respectively.Comment: 13 pages, 2 figures, revise a numbe

    Multiorgan MRI findings after hospitalisation with COVID-19 in the UK (C-MORE): a prospective, multicentre, observational cohort study

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    Introduction: The multiorgan impact of moderate to severe coronavirus infections in the post-acute phase is still poorly understood. We aimed to evaluate the excess burden of multiorgan abnormalities after hospitalisation with COVID-19, evaluate their determinants, and explore associations with patient-related outcome measures. Methods: In a prospective, UK-wide, multicentre MRI follow-up study (C-MORE), adults (aged ≥18 years) discharged from hospital following COVID-19 who were included in Tier 2 of the Post-hospitalisation COVID-19 study (PHOSP-COVID) and contemporary controls with no evidence of previous COVID-19 (SARS-CoV-2 nucleocapsid antibody negative) underwent multiorgan MRI (lungs, heart, brain, liver, and kidneys) with quantitative and qualitative assessment of images and clinical adjudication when relevant. Individuals with end-stage renal failure or contraindications to MRI were excluded. Participants also underwent detailed recording of symptoms, and physiological and biochemical tests. The primary outcome was the excess burden of multiorgan abnormalities (two or more organs) relative to controls, with further adjustments for potential confounders. The C-MORE study is ongoing and is registered with ClinicalTrials.gov, NCT04510025. Findings: Of 2710 participants in Tier 2 of PHOSP-COVID, 531 were recruited across 13 UK-wide C-MORE sites. After exclusions, 259 C-MORE patients (mean age 57 years [SD 12]; 158 [61%] male and 101 [39%] female) who were discharged from hospital with PCR-confirmed or clinically diagnosed COVID-19 between March 1, 2020, and Nov 1, 2021, and 52 non-COVID-19 controls from the community (mean age 49 years [SD 14]; 30 [58%] male and 22 [42%] female) were included in the analysis. Patients were assessed at a median of 5·0 months (IQR 4·2–6·3) after hospital discharge. Compared with non-COVID-19 controls, patients were older, living with more obesity, and had more comorbidities. Multiorgan abnormalities on MRI were more frequent in patients than in controls (157 [61%] of 259 vs 14 [27%] of 52; p5mg/L, OR 3·55 [1·23–11·88]; padjusted=0·025) than those without multiorgan abnormalities. Presence of lung MRI abnormalities was associated with a two-fold higher risk of chest tightness, and multiorgan MRI abnormalities were associated with severe and very severe persistent physical and mental health impairment (PHOSP-COVID symptom clusters) after hospitalisation. Interpretation: After hospitalisation for COVID-19, people are at risk of multiorgan abnormalities in the medium term. Our findings emphasise the need for proactive multidisciplinary care pathways, with the potential for imaging to guide surveillance frequency and therapeutic stratification. Funding: UK Research and Innovation and National Institute for Health Research
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