258 research outputs found

    Shifting Bordering and Rescue Practices in the Central Mediterranean Sea, October 2013–October 2015

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    This counter‐mapping project illustrates the areas of intervention of different operations geared toward rescue and enforcement between 2013 and 2015, including the Italian Navy's “Mare Nostrum” search and rescue mission, the EU border agency Frontex's “Triton” enforcement operation, the humanitarian interventions of commercial vessels, and the action of civil‐society rescue vessels such as those operated by Médecins Sans Frontières (MSF—Doctors Without Borders). The project offers a spatial understanding of the Mediterranean border‐scape, the practices of rescue and enforcement that occur within it, and the risk of sea‐crossing at this particular moment. Through these maps, the Central Mediterranean Sea emerges as a striking laboratory from which novel legal arrangements, surveillance technologies, and institutional assemblages converge

    Shifting Bordering and Rescue Practices in the Central Mediterranean Sea, October 2013-October 2015

    Get PDF
    This counter‐mapping project illustrates the areas of intervention of different operations geared toward rescue and enforcement between 2013 and 2015, including the Italian Navy's “Mare Nostrum” search and rescue mission, the EU border agency Frontex's “Triton” enforcement operation, the humanitarian interventions of commercial vessels, and the action of civil‐society rescue vessels such as those operated by Médecins Sans Frontières (MSF—Doctors Without Borders). The project offers a spatial understanding of the Mediterranean border‐scape, the practices of rescue and enforcement that occur within it, and the risk of sea‐crossing at this particular moment. Through these maps, the Central Mediterranean Sea emerges as a striking laboratory from which novel legal arrangements, surveillance technologies, and institutional assemblages converge

    Postmenopausal hormone therapy in BRCA gene mutation carriers: to whom and which?

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    Introduction: Risk-reducing-salpingo-oophorectomy (RRSO) inevitably leads BRCA mutation carriers to premature menopause. Areas covered: To evaluate the existing evidence for use of postmenopausal hormone therapy (HT) in BRCAmc, after RRSO or menopause occurring naturally, for both breast cancer (BC) survivors and those without BC. Expert opinion: All BC survivors are excluded from any HT treatment: in other BRCAmc, before 51 years of age the benefits of HT overcome the risks after RRSO and/or premature ovarian insufficiency (POF). After 51 years of age, it is important to treat only women with important vasomotor symptoms, after the failure of alternative therapies. Estrogens-only therapy plays a key role in hysterectomized women (HW). In the case of an intact uterus (UW), associations with the lowest dose of progestins/natural progesterone derivatives have to be preferred, as progestins has been shown to play an important role in BC transformation, especially in BRCA1mc. No studies have been performed in BRCAmc with regard to ‘progestin-free’ HT, in particular the old tibolone (both in HW and UW) and the new tissue-selective estrogen complex (in UW). However, preliminary data obtained from the general population are reassuring about the use of these ‘progestin-free’ preparations and BC safety
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