Idiopathic True Aneurysm of the Radial Artery: A Rare Entity

AbstractIntroductionTrue aneurysms of the radial artery are extremely rare. Most cases of Radial artery aneurysm are the result of iatrogenic trauma, however other rare causes such as vascular tumours, connective tissue diseases and occupational injury have also been reported.Case reportA 60-year-old man presented with a pulsating mass in the anatomical snuffbox of the left hand. He underwent distal radial artery ligation and excision of the aneurysm. Histopathology demonstrated this to be a true aneurysm in continuation with the vessel wall.DiscussionThere are only a few cases of true distal radial artery aneurysm described in the literature. Careful examination and pre-operative imaging will help determine the most appropriate surgical management, including the need for vascular reconstruction

Is a multiple excitation of a single atom equivalent to a single excitation of an ensemble of atoms?

Recent technological advances have enabled to isolate, control and measure the properties of a single atom, leading to the possibility to perform statistics on the behavior of single quantum systems. These experiments have enabled to check a question which was out of reach previously: Is the statistics of a repeatedly excitation of an atom N times equivalent to a single excitation of an ensemble of N atoms? We present a new method to analyze quantum measurements which leads to the postulation that the answer is most probably no. We discuss the merits of the analysis and its conclusion.Comment: 3 pages, 3 figure

The “Journey” of Doctoral Study in Applied Psychology: Lived Experiences of Students in Counseling, Clinical, and School Psychology

A qualitative methodology was adopted to explore the lived experiences of doctoral level students in applied psychology. A total of 15 students ranging in age from 24 to 43, who were at varying levels of their doctoral education, participated in individual semi-structured interviews exploring themes related to influences for the pursuit of graduate study, experiences in their program of study, and general reflections of the graduate school journey. All interviews were conducted from a constructivist-interpretivist model, transcribed verbatim, and analyzed using a phenomenological coding approach (Creswell, 2012; Moustakas, 1994). Emergent broad themes included antecedents leading to graduate study, current experience of doctoral education, and reflections on the doctoral experience. Implications for future research are discussed and recommendations for graduate programs based on findings are provided

Magnetization of small lead particles

The magnetization of an ensemble of isolated lead grains of sizes ranging from below 6 nm to 1000 nm is measured. A sharp disappearance of Meissner effect with lowering of the grain size is observed for the smaller grains. This is a direct observation by magnetization measurement of the occurrence of a critical particle size for superconductivity, which is consistent with Anderson's criterion.Comment: 7 pages, 5 figures, Submitted to PR

Helicobacter pylori Eradication in Patients with Immune Thrombocytopenic Purpura: A Review and the Role of Biogeography

Idiopathic thrombocytopenic purpura (ITP) is typically a diagnosis of exclusion, assigned by clinicians after ruling out other identifiable etiologies. Since a report by Gasbarrini et al. in 1998, an accumulating body of evidence has proposed a pathophysiological link between ITP and chronic Helicobacter pylori (H. pylori) infection. Clinical reports have described a spontaneous resolution of ITP symptoms in about 50% of chronic ITP patients following empirical treatment of H. pylori infection, but response appears to be geography dependent. Studies have also documented that ITP patients in East Asian countries are more likely to express positive antibody titers against H. pylori-specific cytotoxic-associated gene A (CagA), a virulence factor that is associated with an increased risk for gastric diseases including carcinoma. While a definitive mechanism by which H. pylori may induce thrombocytopenia remains elusive, proposed pathways include molecular mimicry of CagA by host autoantibodies against platelet surface glycoproteins, as well as perturbations in the phagocytic activity of monocytes. Traditional treatments of ITP have been largely empirical, involving the use of immunosuppressive agents and immunoglobulin therapy. However, based on the findings of clinical reports emerging over the past 20 years, health organizations around the world increasingly suggest the detection and eradication of H. pylori as a treatment for ITP. Elucidating the exact molecular mechanisms of platelet activation in H. pylori-positive ITP patients, while considering biogeographical differences in response rates, could offer insight into how best to use clinical H. pylori eradication to treat ITP, but will require well-designed studies to confirm the suggested causative relationship between bacterial infection and an autoimmune disease state.National Institutes of Health (U.S.) (T320D010978-26)National Institutes of Health (U.S.) (P01CA028842-23)National Institutes of Health (U.S.) (P30ES002109

Obstetrical Complications and Outcome in Two Families with Hereditary Angioedema due to Mutation in the F12 Gene

Backgroud. Hereditary angioedema (HAE) is characterized by recurrent swelling of the skin, the abdomen (causing severe acute pain), and the airways. A recently discovered type caused by mutations in the factor XII gene (designated as HAE type III) occurs mainly in women. Estrogens may play an important role, but few obstetrical complications have been reported. Case. We report the symptoms and obstetrical complications of women in two families with HAE attributable to the p. Thr328Lys mutation in the F12 gene. Clinical manifestations included acute and severe maternal abdominal pain, with transient ascites, laryngeal edema, and fetal and neonatal deaths. Patients had normal C4 levels and a normal C1 inhibitor gene. Administration of C1-inhibitor concentration twice monthly decreased the attack rate in one mother, and its predelivery administration (1000 U) led to the delivery of healthy girls. Conclusions. Obstetricians and anesthesiologists should be aware of this rare cause of unexplained maternal ascites and in utero or fetal death associated with edema

Privatization and State Capacity in Postcommunist Society

Economists have used cross-national regression analysis to argue that postcommunist economic failure is the result of inadequate adherence liberal economic policies. Sociologists have relied on case study data to show that postcommunist economic failure is the outcome of too close adherence to liberal policy recommendations, which has led to an erosion of state effectiveness, and thus produced poor economic performance. The present paper advances a version of this statist theory based on a quantitative analysis of mass privatization programs in the postcommunist world. We argue that rapid large-scale privatization creates severe supply and demand shocks for enterprises, thereby inducing firm failure. The resulting erosion of tax revenues leads to a fiscal crisis for the state, and severely weakens its capacity and bureaucratic character. This, in turn, reacts back on the enterprise sector, as the state can no longer support the institutions necessary for the effective functioning of a modern economy, thus resulting in deindustrialization. Using cross-national regression techniques we find that the implementation of mass privatization programs negatively impacts measures of economic growth, state capacity and the security of property rights.http://deepblue.lib.umich.edu/bitstream/2027.42/40192/3/wp806.pd