15 research outputs found
Detailed analysis of a quench bomb for the study of aluminum agglomeration in solid propellants
A standard quench bomb (QB) â widely used to characterize condensed phase from
metalized solid propellant combustion â is studied in detail. Experimental and
numerical investigations proved that collected particles are mostly unburned
aluminum (Al) agglomerates despite large quenching distances. Particles are
actually found to quench early as propellant surface is swept by inert
pressurant. Further improvements of the QB are proposed which allow measuring
both Al agglomerates and alumina residue with the same setup. Finally, the
results obtained on a typical aluminized ammonium perchlorate (AP) /
hydroxyl-terminated polybutadiene (HTPB) propellant are briefly discussed
New high energetic composite propellants for space applications: refrigerated solid propellant
Cryogenic solid propellants (CSP) are a new kind of chemical propellants that use frozen products to ensure the mechanical resistance of the grain. The objective is to combine the high performances of liquid propulsion and the simplicity of solid propulsion. The CSP concept has few disadvantages. Storability is limited by the need of permanent cooling between motor loading and firing. It needs insulations that increase the dry mass. It is possible to limit significantly these drawbacks by using a cooling temperature near the ambient one. It will permit not to change the motor materials and to minimize the supplementary dry mass due to insulator. The designation âRefrigerated Solid Propellantâ (RPS) is in that case more appropriate as âCryogenic Solid Propellant.â SNPE MatĂ©riaux EnergĂ©tiques is developing new concept of composition e e with cooling temperature as near the ambient temperature as possible. They are homogeneous and the main ingredients are hydrogen peroxide, polymer and metal or metal hydride, they are called âHydroxalaneTM.â This concept allows reaching a high energy level. The expected specific impulse is between 355 and 375 s against 315 s for hydroxyl-terminated polybutadiene (HTPB) / ammonium perchlorate (AP) / Al composition. However, the density is lower than for current propellants, between 1377 and 1462 kg/m3 compared to around 1800 kg/m3 . This is an handicap only for volume-limited application. Works have been carried out at laboratory scale to define the quality of the raw materials and the manufacturing process to realize sample and small grain in a safer manner. To assess the process, a small grain with an internal bore had been realized with a composition based on aluminum and water. This grain had shown very good quality, without any defect, and good bonding properties on the insulator
Evolution de la mesure de la vitesse de combustion des propergols solides
Communication to : Troisiemes journees Paul Vieille, Paris (France), 19-20 octobre 2000SIGLEAvailable from INIST (FR), Document Supply Service, under shelf-number : 22419, issue : a.2001 n.35 / INIST-CNRS - Institut de l'Information Scientifique et TechniqueFRFranc
Total Parenteral Nutrition Plus S-Adenosylmethionine in a Case of Intrahepatic Cholestasis
Improved training tolerance by supplementation with α-Keto acids in untrained young adults: a randomized, double blind, placebo-controlled trial
<p>Abstract</p> <p>Background</p> <p>Exercise causes a variety of physiological and metabolic changes that can in turn reduce exercise tolerance. One of the potential mechanisms responsible for fatigue is âexercise-induced hyperammonemiaâ. Previous studies have shown that supplementation with amino acids can increase training tolerance. The α-keto acids are biochemical analogs of amino acids and can be converted to amino acids through transamination, thus reducing the cellular ammonia level. This double blind, placebo-controlled study was designed to investigate the effects of α-keto acid supplementation (KAS) on training tolerance, training effect, and stress-recovery state.</p> <p>Methods</p> <p>Thirty-three untrained young male adults underwent four weeks of training (5 sessions/week; 30 minutes running at the individual anaerobic threshold followed by 3 x 3 minute sprints/each session). Throughout the 4âweeks of training and one week of recovery, subjects took α-ketoglutarate (AKG group, 0.2âg/kg/d, nâ=â9), branched-chain keto acids (BCKA group, 0.2âg/kg/d, nâ=â12) or isocaloric placebo (control group, nâ=â12) daily.</p> <p>Results</p> <p>The 4<sup>th</sup> week training volume, maximum power output and muscle torque were higher in the AKG group (175â±â42âmin, 412â±â49 Watts and 293â±â58 Newton meters, respectively, P<0.05) and the BCKA group (158â±â35, 390â±â29 and 273â±â47, P<0.05) than in the control group (92â±â70, 381â±â67 and 233â±â43). The general stress and emotional exhaustion as assessed by the rest-stress-questionnaire-sport after the 3<sup>rd</sup> week of training increased significantly in the control group (P<0.05), but not in the KAS groups.</p> <p>Conclusions</p> <p>Under KAS, subjects could bear a higher training volume and reach a higher power output and peak muscle torque, accompanied by a better stress-recovery-state. Thus, KAS improves exercise tolerance and training effects along with a better stress-recovery state. Whether the improved training tolerance by KAS is associated with effects on ammonia homeostasis requires further observation.</p
Constitutive expression of bergaptol O-methyltransferase in Glehnia littoralis cell cultures.
We investigated whether exogenously supplied precursors of bergapten, namely umbelliferone, psoralen and bergaptol, could be utilized to produce bergapten without elicitation in Glehnia littoralis cell suspension cultures. The levels of added psoralen and bergaptol in the medium soon decreased, and this was followed by the detection of bergapten in both culture fluid and cells. Umbelliferone was also incorporated but in this case no bergapten was produced; instead, skimmin, umbelliferone monoglucoside, was detected. To determine whether conversion of psoralen to bergapten was due to enzyme induction by precursor feeding, the transcript accumulations and enzyme activities of bergaptol O-methyltransferase (BMT, EC 2.1.1.69), which catalyzes the last step of bergapten synthesis, and of phenylalanine ammonia-lyase (PAL, EC 4.3.1.5), which catalyzes the initial step of the phenylpropanoid biosynthetic pathway and is known as a marker enzyme of elicitation, were examined. The results showed that both the expression and the activity of BMT were always detected in all cells, including control cells. Since PAL was slightly induced in the cells supplied with/without precursors, phenylethyl alcohol (PEA, a competitive inhibitor of PAL) was applied to suspension cells prior to the addition of psoralen. PAL activity was effectively inhibited by PEA at 1-5 mM concentrations. Under these conditions, PEA did not affect bergapten production by cell cultures fed with psoralen at all. These results demonstrate that BMT is constitutively expressed in G. littoralis cell cultures