Stem cells-based and molecular-based approaches in regenerative dentistry: A topical review

Regenerative medicine is a growing branch of medicine aimed to treat damaged or lost tissues, to promote tissue formation and to restore both aesthetics and function. In the last years, several scientific articles have been focused on the regenerative procedures aimed to increase the survival rate of compromised teeth; the most effective approaches have been based on molecularbased and on cellular-based protocols; however, to date, both these techniques have not been carefully analysed and discussed, to know in details the advantages of each of them

Borophene is a promising 2D allotropic material for biomedical devices

Allotropic 2D materials are the new frontier of materials science, due to their unique strategic properties and application within several sciences. Allotropic 2D materials have shown tunable physical, chemical, biochemical, and optical characteristics, and among the allotropic materials, graphene has been widely investigated for its interesting properties, which are highly required in biomedical applications. Recently, the synthesis of thin 2D boron sheets, developed on Ag(111) substrates, was able to create a 2D triangular structure called borophene (BO). Borophene has consistently shown anisotropic behavior similar to graphene. In this topical review, we will describe the main properties and latest applications of borophene. This review will critically describe the most interesting uses of borophene as part of electronic and optical circuits. Moreover, we will report how borophene can be an innovative component of sensors within biomedical devices, and we will discuss its use in nanotechnologies and theranostic applications. The conclusions will provide insight into the latest frontiers of translational medicine involving this novel and strategic 2D allotropic material

Methodological approach of construction business failure prediction studies: a review

© 2016 Informa UK Limited, trading as Taylor & Francis Group. Performance of bankruptcy prediction models (BPM), which partly depends on the methodological approach used to develop it, has virtually stagnated over the years. The methodological positions of BPM studies were thus investigated. Systematic review was used to search and retrieve 70 journal articles and doctoral theses. Their “general methods” and “philosophical underpinnings” were investigated using summary of findings tables and meta-analysis. “General methods” results showed positive trends in terms of techniques being used, error cost consideration and model validation, with some use of skewed data being the main drawback. For “philosophical underpinnings”, positivism paradigm was discovered to be at the core of BPM studies. This is deemed inadequate because of the need to consider industries’ dynamism, financial variables flaws and social factors which actually lead to the financial status of firms. The pragmatism paradigm using mixed method is proposed. A research design framework for executing the proposed methodology is presented. This will help BPM developers go through more rigorous and robust methodology to deliver better and more valid models. Limitations of study include not reviewing studies not reported in English language and impact of different countries’ accounting practices on ratios. Limited availability of theses’ database resulted in reviewing only four theses