Carotenoid intake and supplementation in cancer pro and con

The aim of this review is to summarize the literature data concerning statistical correlations between carotenoid intake and cancer and to provide evidence, if any, that can justify carotenoid supplementation in protocols designed for the prevention and the treatment of cancer diseases. Particular attention will be drawn to lung cancer because of its surprisingly high incidence in cigarette smokers and asbestos workers who received high doses of beta-carotene. The efficacy of carotenoids and retinol as adjuvants in the therapeutic procedures against cancer and the clinical indications for carotenoid supplementation will be discussed