4,618 research outputs found
Focused Crossed Andreev Reflection
We consider non-local transport in a system with one superconducting and two
normal metal terminals. Electron focusing by weak perpendicular magnetic fields
is shown to tune the ratio between crossed Andreev reflection (CAR) and
electron transfer (ET) in the non-local current response. Additionally,
electron focusing facilitates non-local signals between normal metal contacts
where the separation is as large as the mean free path rather than being
limited by the coherence length of the superconductor. CAR and ET can be
selectively enhanced by modulating the magnetic field
Non-uniform spin wave softening in 2D magnonic crystals as a tool for opening omnidirectional magnonic band gaps
By means of the plane wave method we study spin wave dynamics in
two-dimensional bi-component magnonic crystals based on a squeezed hexagonal
lattice and consist of a permalloy thin film with cobalt inclusions. We explore
the dependence of a spin wave frequency on the external magnetic field,
especially in weak fields where the mode softening takes place. For considered
structures, the mode softening proves to be highly non-uniform on both the mode
number and the wave vector. We found this effect to be responsible for the
omnidirectional band gap opening. Moreover, we show that the enhancement of the
demagnetizing field caused by the squeezing of the structure is of crucial
importance for the non-uniform mode softening. This allows us to employ this
mechanism to design magnonic gaps with different sensitivity for the tiny
change of the external field. The effects we have found should be useful in
designing and optimization of spin wave filters highly tunable by a small
external magnetic field.Comment: Final versio
Proposal Flow: Semantic Correspondences from Object Proposals
Finding image correspondences remains a challenging problem in the presence
of intra-class variations and large changes in scene layout. Semantic flow
methods are designed to handle images depicting different instances of the same
object or scene category. We introduce a novel approach to semantic flow,
dubbed proposal flow, that establishes reliable correspondences using object
proposals. Unlike prevailing semantic flow approaches that operate on pixels or
regularly sampled local regions, proposal flow benefits from the
characteristics of modern object proposals, that exhibit high repeatability at
multiple scales, and can take advantage of both local and geometric consistency
constraints among proposals. We also show that the corresponding sparse
proposal flow can effectively be transformed into a conventional dense flow
field. We introduce two new challenging datasets that can be used to evaluate
both general semantic flow techniques and region-based approaches such as
proposal flow. We use these benchmarks to compare different matching
algorithms, object proposals, and region features within proposal flow, to the
state of the art in semantic flow. This comparison, along with experiments on
standard datasets, demonstrates that proposal flow significantly outperforms
existing semantic flow methods in various settings.Comment: arXiv admin note: text overlap with arXiv:1511.0506
Yes-go cross-couplings in collections of tensor fields with mixed symmetries of the type (3,1) and (2,2)
Under the hypotheses of analyticity, locality, Lorentz covariance, and
Poincare invariance of the deformations, combined with the requirement that the
interaction vertices contain at most two space-time derivatives of the fields,
we investigate the consistent cross-couplings between two collections of tensor
fields with the mixed symmetries of the type (3,1) and (2,2). The computations
are done with the help of the deformation theory based on a cohomological
approach in the context of the antifield-BRST formalism. Our results can be
synthesized in: 1. there appear consistent cross-couplings between the two
types of field collections at order one and two in the coupling constant such
that some of the gauge generators and of the reducibility functions are
deformed, and 2. the existence or not of cross-couplings among different fields
with the mixed symmetry of the Riemann tensor depends on the indefinite or
respectively positive-definite behaviour of the quadratic form defined by the
kinetic terms from the free Lagrangian.Comment: 35 page
Imatinab mesylate treatment in Chronic Myeloid Leukemia (CML)- understanding the fundamental pharmacokinetic and pharmacogenetic mechanisms for variation in response
Although lmatinib mesylate (IM) is the gold standard drug for Chronic Myeloid Leukemia (CML)
treatment, resistance to IM emerges in a significant number of patients. Resistance could be due to
several factors. Pharmacokinetic variability as a result of genetic polymorphisms in IM metabolizing
genes could be a potential factor. This study was undertaken to investigate the genotype frequencies
and the impact of ORM1 520G>A, PXR 1792A>G, CAR 540C>T, CYP3A4 878T>C and CYP3A5
6986A>G polymorphisms towards CML susceptibility risk and IM response. A total of 540 subjects (270
CML patients and 250 normal healthy controls) have been recruited in this study. Genotyping was
performed and the association between allelic variants and CML susceptibility risk and response to IM
treatment were assessed by means of odds ratio (OR) with 95% confident interval s calculated by
logistic regression. Results showed that PXR 1792A>G, CAR 540C>T and CYP3A5 6986A>G were
significantly associated with IM responses and CAR 540C>T, CYP3A4 878T>C and CYP3A5 6986A>G
were significantly associated with CML susceptibility risk. Further study should be done on a larger
scale to validate whether this polymorphism can be used as a predictive biomarker for identifying
resistance development among CML patients undergoing IM treatment
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