6,292 research outputs found

    A system to support dissemination of knowledge and sharing of experiences in the working environment

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    In the information era enterprises strive to be productive and efficient. One feature of this goal is to engage their employees in education programmes, help them gain new experiences and knowledge and adapt to an ever-changing working environment. Such programmes require thorough design in order to achieve satisfactory results. Lately, enterprises recognising the role technology can play in the education of their employees, have adopted systems that supplement the traditional educational model with mechanisms that enable the sharing of experiences and knowledge [5]. In this paper we describe an architecture and a system prototype that allows users to search easily for information, interact with colleagues and share experiences, to compose and disseminate best practices and knowledge. The design of this system is based on insights gained from the operation of the Greek Taxation System

    Examining the importance of Aberdeenshire (UK) coastal waters for North Sea bottlenose dolphins (Tursiops truncates)

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    Using land- and vessel-based surveys, data on the relative abundance, distribution and habitat use of bottlenose dolphins (Tursiops truncatus) in Aberdeenshire waters were collected between 1999 and 2001. Bottlenose dolphins were present throughout the year, with peak abundance during the months of March to May. The occurrence of calves was seasonal, With the proportion of calves highest during the spring months. Foraging behaviour was recorded mainly in the vicinity of Aberdeen harbour. Dolphins photographed in Aberdeenshire waters were successfully matched and confirmed as Moray Firth animals. The results of the present study suggest that Moray Firth bottlenose dolphins utilize Aberdeenshire waters more frequently than previously reported. Aberdeen harbour is apparently an important feeding area, and Aberdeenshire waters are regularly used by another-calf pairs. This has important management implications since this area of coastline does not currently form part of the designated Special Area of Conservation (SAC) for this population

    Using machine learning techniques to automate sky survey catalog generation

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    We describe the application of machine classification techniques to the development of an automated tool for the reduction of a large scientific data set. The 2nd Palomar Observatory Sky Survey provides comprehensive photographic coverage of the northern celestial hemisphere. The photographic plates are being digitized into images containing on the order of 10(exp 7) galaxies and 10(exp 8) stars. Since the size of this data set precludes manual analysis and classification of objects, our approach is to develop a software system which integrates independently developed techniques for image processing and data classification. Image processing routines are applied to identify and measure features of sky objects. Selected features are used to determine the classification of each object. GID3* and O-BTree, two inductive learning techniques, are used to automatically learn classification decision trees from examples. We describe the techniques used, the details of our specific application, and the initial encouraging results which indicate that our approach is well-suited to the problem. The benefits of the approach are increased data reduction throughput, consistency of classification, and the automated derivation of classification rules that will form an objective, examinable basis for classifying sky objects. Furthermore, astronomers will be freed from the tedium of an intensely visual task to pursue more challenging analysis and interpretation problems given automatically cataloged data

    Effects of tumour necrosis factor-α on BrdU incorporation in cultured human enterocytes

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    Bromodeoxyuridine incorporation is a useful method for studying the pattern of DNA synthesis in proliferating cells. The distribution pattern of incorporated BrdU in villus enterocytes of duodenal explants was analysed after exposure to TNFα in organ culture. TNFα caused a consistent, low level uptake of BrdU in the portion of the nucleus close to the nuclear membrane, this pattern was absent from the control cultures. As these epithelial cells are terminally arrested in G0, the BrdU incorporation was thought not to be due to S phase DNA synthesis, but rather a response to the cytotoxic influence of TNFα. Microtitre plate proliferation assays of cell density and DNA synthesis were devised to study the effects of TNFα on confluent monolayers of the human foetal jejunal cell line I407 and the mouse fibrosarcoma cell line L929. Both cell lines showed a similar response to TNFα. Exposure to TNFα alone did not reduce cell numbers but did cause a significant increase in DNA synthesis (p < 0.05). When cycloheximtde was added in tandem with TNFα there was a significant reduction in cell number (p < 0.001) and level of DNA synthesis (p < 0.01) indicative of cell death. The DNA of cells exposed to TNFα and cycloheximide was fragmented when viewed on an electrophoresis gel. The results show that BrdU incorporation might be a good indicator of damage to the DNA of cells after cytotoxic insult. TNFα may be responsible for villus enterocyte damage in enteropathies such as coeliac disease and GVHR of the small bowel

    Infrared observations of the gravitational lens system B1422 + 231

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    Images of the multiple-component radio source B1422 + 231 at 2.2 μm show the structure of this source to be essentially the same at radio and infrared frequencies. The most natural explanation for this achromatic structure is gravitational lensing

    Searches for New Quarks and Leptons Produced in Z-Boson Decay

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    We have searched for events with new-particle topologies in 390 hadronic Z decays with the Mark II detector at the SLAC Linear Collider. We place 95%-confidence-level lower limits of 40.7 GeV/c^2 for the top-quark mass, 42.0 GeV/c^2 for the mass of a fourth-generation charge - 1/3 quark, and 41.3 GeV/c^2 for the mass of an unstable Dirac neutral lepton

    Measurement of Z Decays into Lepton Pairs

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    We present measurements by the Mark II experiment of the ratios of the leptonic partial widths of the Z boson to the hadronic partial width. The results are Γ_(ee)/Γ_(had)=0.037_(-0.012^()+0.016),Γ_(µµ)/Γ_(had)=0.053-_(0.015)^(+0.020), and Γ_(ττ)/Γ_(had)=0.066_(-0.017)^(+0.021), in good agreement with the standard-model prediction of 0.048. From the average leptonic width result, Γ_(ll)/Γ_(had)=0.053_(-0.009)^(+0.010), we derive Γ_(had)=1.56_(-0.24)^(+0.28) GeV. We find for the vector coupling constants of the tau and muon v_τ^2=0.31±0.31_(-0.30)^(+0.43) and v_μ^2=0.05±0.30_(-0.23)^(+0.34)
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