Structural studies of mesoporous ZrO2_{2}-CeO2_{2} and ZrO2_{2}-CeO2_{2}/SiO2_{2} mixed oxides for catalytical applications

In this work the synthesis of ZrO$_{2}$-CeO$_{2}$ and ZrO$_{2}$-CeO$_{2}$/SiO$_{2}$ were developed, based on the process to form ordered mesoporous materials such as SBA-15 silica. The triblock copolymer Pluronic P-123 was used as template, aiming to obtain crystalline single phase walls and larger specific surface area, for future applications in catalysis. SAXS and XRD results showed a relationship between ordered pores and the material crystallization. 90% of CeO$_{2}$ leaded to single phase homogeneous ceria-zirconia solid solution of cubic fluorite structure (Fm$\bar{3}$m). The SiO$_{2}$ addition improved structural and textural properties as well as the reduction behavior at lower temperatures, investigated by XANES measurements under H$_{2}$ atmosphere

The CloudSME Simulation Platform and its Applications: A Generic Multi-cloud Platform for Developing and Executing Commercial Cloud-based Simulations

Simulation is used in industry to study a large variety of problems ranging from increasing the productivity of a manufacturing system to optimizing the design of a wind turbine. However, some simulation models can be computationally demanding and some simulation projects require time consuming experimentation. High performance computing infrastructures such as clusters can be used to speed up the execution of large models or multiple experiments but at a cost that is often too much for Small and Medium-sized Enterprises (SMEs). Cloud computing presents an attractive, lower cost alternative. However, developing a cloud-based simulation application can again be costly for an SME due to training and development needs, especially if software vendors need to use resources of different heterogeneous clouds to avoid being locked-in to one particular cloud provider. In an attempt to reduce the cost of development of commercial cloud-based simulations, the CloudSME Simulation Platform (CSSP) has been developed as a generic approach that combines an AppCenter with the workflow of the WS-PGRADE/gUSE science gateway framework and the multi-cloud-based capabilities of the CloudBroker Platform. The paper presents the CSSP and two representative case studies from distinctly different areas that illustrate how commercial multi-cloud-based simulations can be created

The Penetration–Aspiration Scale: Adaptation to Open Partial Laryngectomy and Reliability Analysis

A standard for assessing swallowing function after open partial horizontal laryngectomy (OPHL) is still not established. The variability in the measures used to investigate swallowing functional outcomes after OPHL limits the communication among clinicians and the possibility to compare and combine results from different studies. The study aims to adapt the PAS to the altered anatomy after OPHLs using fiberoptic endoscopic evaluation of swallowing (FEES) and to test its reliability. To adapt the PAS, two landmarks were identified: the entry of the laryngeal vestibule and the neoglottis. Ninety patients who underwent an OPHL were recruited (27 type I, 31 type II and 32 type III). FEES was performed and video-recorded. Two speech and language therapists (SLTs) independently rated each FEES using the PAS adapted for OPHL (OPHL-PAS). FEES recordings were rated for a second time by both SLTs at least 15 days from the first video analysis. Inter- and intra-rater agreement was assessed using unweighted Cohen's kappa. Overall, inter-rater agreement of the OPHL-PAS was k\u2009=\u20090.863, while intra-rater agreement was k\u2009=\u20090.854. Concerning different OPHL types, inter- and intra-rater agreement were k\u2009=\u20090.924 and k\u2009=\u20090.914 for type I, k\u2009=\u20090.865 and k\u2009=\u20090.790 for type II, and k\u2009=\u20090.808 and k\u2009=\u20090.858 for type III, respectively. The OPHL-PAS is a reliable scale to assess the invasion of lower airway during swallowing in patients with OPHL using FEES. The study represents the first attempt to define standard tools to assess swallowing functional outcome in this population

Echocardiographic screening in pediatric asymptomatic or paucisymptomatic coronavirus disease 2019 outpatients: Is it a useful test or an excess of zeal?

IntroductionData regarding echocardiographic findings during follow-up of asymptomatic or pauci-symptomatic coronavirus disease 2019 (COVID-19) are scarce in pediatric patients. The aim of the present study is to assess post-COVID-19 sequelae through echocardiography in children who have experienced mild SARS-CoV-2.MethodsThis single-center, retrospective, observational study enrolled a cohort of 133 pediatric outpatients, born between 2005 and 2022, with a history of asymptomatic or paucisymptomatic SARS-CoV-2 infection, who underwent transthoracic echocardiographic (TTE) evaluation at an outpatient pediatric clinic in Northern Italy.ResultsThe percentage of the pediatric activity of the clinic which was focused on post-COVID evaluation was not negligible, representing almost 10% of the similar to 1500 pediatric patients examined from 1 January 2021 to 31 August 2022. According to ACEP classification, children enrolled in this study had previously experienced in 72.9% (97) asymptomatic COVID-19 and nearly 27% (36) a mild illness. Clinical and instrumental examinations did not show any relevant abnormality in the functional [left ventricular ejection fraction (LVEF), tricuspid annular plane systolic excursion (TAPSE), pulmonary artery systolic pressure (PASP)] or structural [interventricular septum diameter (IVSd), left ventricular internal diameter (LViD, end-diastolic volume (EDV), left atrium volume (LAV)] parameters examined related to SARS-CoV-2 infection in the total of 133 children.ConclusionAccording to our results, children who experienced an asymptomatic or mild SARS-CoV-2 infection should not be systematically investigated with second-level techniques, such as TTE, in the absence of clinical suspicion or other risk conditions such as congenital heart diseases, comorbidities or risk factors

Enabling Cloud-based Computational Fluid Dynamics with a Platform-as-a-Service Solution

Computational Fluid Dynamics (CFD) is widely used in manufacturing and engineering from product design to testing. CFD requires intensive computational power and typically needs high performance computing to reduce potentially long experimentation times. Dedicated high performance computing systems are often expensive for small-to-medium enterprises (SMEs). Cloud computing claims to enable low cost access to high performance computing without the need for capital investment. The CloudSME Simulation Platform aims to provide a flexible and easy to use cloud-based Platform-as-a-Service (PaaS) technology that can enable SMEs to realize the benefits of high performance computing. Our Platform incorporates workflow management and multi-cloud implementation across various cloud resources. Here we present the components of our technology and experiences in using it to create a cloud-based version of the TransAT CFD software. Three case studies favourably compare the performance of a local cluster and two different clouds and demonstrate the viability of our cloud-based approach