INSIGHT OF METHANOLIC EXTRACT OF VENTILAGO MADERASPATANA LEAVES ON HEPATOPROTECTIVE ACTIVITY UNDER STREPTOZOTOCIN-INDUCED DIABETIC RATS

Objective: The methanolic leaf extract of Ventilago maderaspatana (MEVML, 200 mg/kg body weight [b.w.]) was investigate to hepatoprotective activity under streptozotocin-induced (45 mg/kg b.w.) diabetic (Di) rats. Methods: In the present study, we determined the blood glucose levels, b.w., insulin, creatinine, and bilirubin levels in normal, Di, Di treated with MEVML and positive control rats. Results: The Di rats shown adverse changes in blood glucose levels, b.w., insulin, creatinine, and bilirubin levels when compared to other group rats. Reverse the adverse changes in the above parameters when treated the Di rats with MEVML Conclusion: The MEVML shown anti-diabetic activity and reverse the adverse changes in the above parameters in liver so that the MEVML supported the traditional claim of the hepatoprotective activity under Di condition

VALUE CHAIN MODEL FOR STEEL MANUFACTURING SECTOR: A CASE STUDY

ABSTRAC

Ocimum sanctum: a review on the pharmacological properties

Herbal medicine, the backbone of traditional medicine in many countries have played an important role in curing the diseases of humans since ancient time. Medicinal plants are great source of bioactive compounds and chemical structures that have potential beneficial effects. The present review compiles information on ethnopharmacologically useful information and pharmacological properties of Ocimum sanctum. Ocimum sanctum (OS) has many medicinal properties like antioxidant, antidiabetic, antiulcer, anticancer, antibacterial, antifungal and other. The phytochemicals compounds of Ocimum, alkaloids, flavonoids, phenolics, essential oils, tannins and saponins play an important role in herbal medicine. Bioactive compounds of Ocimum responsible for its various medicinal properties and their effects at the molecular level need to be investigated in more detail. Furthermore, pharmacological properties of bioactive compounds in Ocimum sanctum are required to confirm the ethnomedicinal claims of Ocimum sanctum for pharmaceutical therapeutic applications

INTERNATIONAL JOURNAL OF PHARMACY & LIFE SCIENCES Screening of potential efficacy of dietary ginger on ethanol induced oxidative stress in rat cardiac tissue: A study on changes in basic metabolic profiles

Abstract The present study was premeditated to examine the possible mechanisms where by ginger (Zingiber officinale) could protect cardiac tissue from alcohol toxicity in rats. The carbohydrate metabolic profiles like total carbohydrates, pyruvate, total proteins, free amino acids and lactate levels were measured in heart tissue. The total carbohydrates, pyruvate, and total proteins were significant declined while free amino acids, lactate levels were significant increased in alcohol intoxicated rats. Whereas with ginger (200 mg/kg body weight) treatment shown significant increase in the total carbohydrates, total proteins and pyruvate levels, whereas free amino acids, lactate levels were significant drop in the cardiac tissues. From the present study, we conclude that ginger protects the heart tissue from alcohol toxicity in rats, this may be due to the presence of many bioactive compounds in ginger

Structural and thermal studies of silver nanoparticles and electrical transport study of their thin films

This work reports the preparation and characterization of silver nanoparticles synthesized through wet chemical solution method and of silver films deposited by dip-coating method. X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM), field emission transmission electron microscopy (FETEM), high-resolution transmission electron microscopy (HRTEM), selected area electron diffraction (SAED), and energy dispersive spectroscopy (EDX) have been used to characterize the prepared silver nanoparticles and thin film. The morphology and crystal structure of silver nanoparticles have been determined by FESEM, HRTEM, and FETEM. The average grain size of silver nanoparticles is found to be 17.5 nm. The peaks in XRD pattern are in good agreement with that of face-centered-cubic form of metallic silver. TGA/DTA results confirmed the weight loss and the exothermic reaction due to desorption of chemisorbed water. The temperature dependence of resistivity of silver thin film, determined in the temperature range of 100-300 K, exhibit semiconducting behavior of the sample. The sample shows the activated variable range hopping in the localized states near the Fermi level

Structural, optical and magnetic properties of Cu doped CeO2 nano powders synthesized by solid state reaction

In this research work, the structural, optical, and magnetic properties of Ce _1−x Cu _x O nanoparticles have been reported. Solid state reaction technique was employed to synthesize the nanoparticle samples. The synthesized materials were analysed structural properties from x-ray diffraction (XRD) observed that the crystallite size increased from16.9 nm to 40.43 nm and the lattice constant increased with increase of Cu doping concentration, and the structural properties after doping confirm the absence of other phase and synthesized samples had a cubic structure. Using SEM and EDAX, the nanoparticles surface morphology and elemental composition in investigated. The nanoparticles have a spherical shape and approximately the expected stoichiometric ratio. The optical band gap of copper doped cerium oxide nanoparticles is calculated and found the band gap decreased with increased dopant concentration. Ce _1−x Cu _x O nanoparticles using photoluminescence (PL) analysis at excitation wavelengths of 350 nm revealed emissions of the violet, blue, green, and red regions within the range of 350–700 nm. Vibrating sample magnetometer was found that the samples were room temperature ferromagnetic in nature and strength of magnetic moment increased with increase of doping concentration