A photometric and spectroscopic investigation of star formation in the very young open cluster NGC6383

The very young open cluster NGC 6383 centered on the O-star binary HD 159176 is an interesting place for studying the impact of early-type stars with strong radiation fields and powerful winds on the formation processes of low-mass stars. To investigate this process, it is necessary to determine the characteristics (age, presence, or absence of circumstellar material) of the population of low-mass pre-main-sequence (PMS) stars in the cluster. We obtained deep U B V (R I)_c H-alpha photometric data of the entire cluster as well as medium-resolution optical spectroscopy of a subsample of X-ray selected objects. Our spectroscopic data reveal only very weak H-alpha emission lines in a few X-ray selected PMS candidates. We photometrically identify a number of H-alpha emission candidates but their cluster membership is uncertain. We find that the fainter objects in the field of view have a wide range of extinction (up to A_V = 20), one X-ray selected OB star having A_V ~ 8. Our investigation uncovers a population of PMS stars in NGC 6383 that are probably coeval with HD 159176. In addition, we detect a population of reddened objects that are probably located at different depths within the natal molecular cloud of the cluster. Finally, we identify a rather complex spatial distribution of H-alpha emitters, which is probably indicative of a severe contamination by foreground and background stars.Comment: Accepted for publication in Astronomy & Astrophysic

Avaliação agroeconômica de sistemas consorciados de cenoura e rúcula.

Um dos sistemas de cultivo que pode contribuir para a realização de uma agricultura sustentável economicamente é a consorciação de culturas. Estudos coprovam que rendimentos advindos de sistemas consorciados de hortaliças, apresentam-se vantajosos em relação aos obtidos nas culturas soslteiras

Cytoplasmic PML promotes TGF-β-associated epithelial–mesenchymal transition and invasion in prostate cancer

Epithelial–mesenchymal transition (EMT) is a key event that is involved in the invasion and dissemination of cancer cells. Although typically considered as having tumour-suppressive properties, transforming growth factor (TGF)-β signalling is altered during cancer and has been associated with the invasion of cancer cells and metastasis. In this study, we report a previously unknown role for the cytoplasmic promyelocytic leukaemia (cPML) tumour suppressor in TGF-β signalling-induced regulation of prostate cancer-associated EMT and invasion. We demonstrate that cPML promotes a mesenchymal phenotype and increases the invasiveness of prostate cancer cells. This event is associated with activation of TGF-β canonical signalling pathway through the induction of Sma and Mad related family 2 and 3 (SMAD2 and SMAD3) phosphorylation. Furthermore, the cytoplasmic localization of promyelocytic leukaemia (PML) is mediated by its nuclear export in a chromosomal maintenance 1 (CRM1)-dependent manner. This was clinically tested in prostate cancer tissue and shown that cytoplasmic PML and CRM1 co-expression correlates with reduced disease-specific survival. In summary, we provide evidence of dysfunctional TGF-β signalling occurring at an early stage in prostate cancer. We show that this disease pathway is mediated by cPML and CRM1 and results in a more aggressive cancer cell phenotype. We propose that the targeting of this pathway could be therapeutically exploited for clinical benefit

Photometric variability of the Herbig Ae star HD 37806

The more massive counterparts of T Tauri stars, Herbig Ae/Be stars, are known to vary in a complex way with no variability mechanism clearly identified. We attempt to characterize the optical variability of HD~37806 (MWC 120) on time scales ranging between minutes and several years. A continuous, one-minute resolution, 21 day-long sequence of MOST (Microvariability & Oscillations of STars) satellite observations has been analyzed using wavelet, scalegram and dispersion analysis tools. The MOST data have been augmented by sparse observations over 9 seasons from ASAS (All Sky Automated Survey), by previously non-analyzed ESO (European Southern Observatory) data partly covering 3 seasons and by archival measurements dating back half a century ago. Mutually superimposed flares or accretion instabilities grow in size from about 0.0003 of the mean flux on a time scale of minutes to a peak-to-peak range of <~0.05 on a time scale of a few years. The resulting variability has properties of stochastic "red" noise, whose self-similar characteristics are very similar to those observed in cataclysmic binary stars, but with much longer characteristic time scales of hours to days (rather than minutes) and with amplitudes which appear to cease growing in size on time scales of tens of years. In addition to chaotic brightness variations combined with stochastic noise, the MOST data show a weakly defined cyclic signal with a period of about 1.5 days, which may correspond to the rotation of the star.Comment: Accepted for publication by Astron. & Astroph. 8 pages, 9 figures. For some reason Fig.5 incorrectly shows in arXiv: Contours OK, gray scale no