200 research outputs found
Solid Waste Management in Rural Communities of Developing Countries: An Overview of Challenges and Opportunities
Solid waste management (SWM) in rural areas of many low- and middle-income countries (LMICs) represents a critical and underrated topic. However, almost half of the world's population still lives in rural areas and an adequate SWM is crucial in reducing environmental and health threats. A lack of knowledge and appropriate tools often leads to inappropriate practices such as waste dumping and uncontrolled burning. However, appropriate methods can transform waste into resources and even guarantee a revenue source. This manuscript provides an overview of the state of the knowledge characterising SWM in rural communities of LMICs, analysing common practices and principal issues. Different solid waste fractions are considered. Virtuous approaches are presented, taking into account recent sustainable solutions. Considering that a relevant part of the world population is still living in rural areas, the benefits associated with an appropriate SWM may be enormous. Such activities may improve local conditions from social, environmental and health perspectives; furthermore, they may have a global impact on facing climate change and environmental pollution
A Simplified Model for Estimating Household Air Pollution in Challenging Contexts: A Case Study from Ghana
Almost three billion people rely primarily on inefficient and polluting cooking systems worldwide. Household air pollution is a direct consequence of this practice, and it is annually associated with millions of premature deaths and diseases, mainly in low- and lower-middle-income countries. The use of improved cookstoves often represents an appropriate solution to reduce such health risks. However, in the distribution of such units, it can be necessary to prioritize the beneficiaries. Thus, in this study, we conducted field research involving five rural villages in the Northern part of Ghana, where using three-stone fires or rural stoves was common. Concentrations of PM2.5, PM10, and carbon monoxide (CO) were measured indoors and outdoors. Considering each field mission lasted less than 24 h, assumptions were made so as to calculate the average pollutant concentrations in 24 h through a new, simplified equation that combined efficiency and cost-savings by shortening field assessments. The obtained values were compared with international guidelines. The results showed that PM2.5 and PM10 limits were overstepped in two villages, which should thus be prioritized. However, further research will be necessary to strengthen and validate our proposed equation, which must be seen as a starting point
Multivariate approximation: Theory and applications 2020
A summary of the main facts about the Conference ‘Multivariate Approximation: Theory and Applications’ (MATA 2020) held at the Department of Mathematics and Computer Science of the University of Perugia (Italy), on January 16-18, 2020 and the contents of the associated Special Issue appearing on Dolomites Research Notes on Approximation, are here reported
Critical Exponents of the 3D Ising Universality Class From Finite Size Scaling With Standard and Improved Actions
We propose a method to obtain an improved Hamiltonian (action) for the Ising
universality class in three dimensions. The improved Hamiltonian has suppressed
leading corrections to scaling. It is obtained by tuning models with two
coupling constants. We studied three different models: the +1,-1 Ising model
with nearest neighbour and body diagonal interaction, the spin-1 model with
states 0,+1,-1, and nearest neighbour interaction, and phi**4-theory on the
lattice (Landau-Ginzburg Hamiltonian). The remarkable finite size scaling
properties of the suitably tuned spin-1 model are compared in detail with those
of the standard Ising model. Great care is taken to estimate the systematic
errors from residual corrections to scaling. Our best estimates for the
critical exponents are nu= 0.6298(5) and eta= 0.0366(8), where the given error
estimates take into account the statistical and systematic uncertainties.Comment: 55 pages, 12 figure
Block Spin Effective Action for 4d SU(2) Finite Temperature Lattice Gauge Theory
The Svetitsky-Yaffe conjecture for finite temperature 4d SU(2) lattice gauge
theory is confirmed by observing matching of block spin effective actions of
the gauge model with those of the 3d Ising model. The effective action for the
gauge model is defined by blocking the signs of the Polyakov loops with the
majority rule. To compute it numerically, we apply a variant of the IMCRG
method of Gupta and Cordery.Comment: LaTeX2e, 22 pages, 8 Figure
Bone marrow failure may be caused by chromosome anomalies exerting effects on RUNX1T1 gene
Background: The majority of the cases of bone marrow failure syndromes/aplastic anaemias (BMFS/AA) are non-hereditary and considered idiopathic (80-85%). The peripheral blood picture is variable, with anaemia, neutropenia and/or thrombocytopenia, and the patients with idiopathic BMFS/AA may have a risk of transformation into a myelodysplastic syndrome (MDS) and/or an acute myeloid leukaemia (AML), as ascertained for all inherited BMFS. We already reported four patients with different forms of BMFS/AA with chromosome anomalies as primary etiologic event: the chromosome changes exerted an effect on specific genes, namely RUNX1, MPL, and FLI1, leading to the disease. Results: We report two further patients with non-hereditary BM failure, with diagnosis of severe aplastic anaemia and pancytopenia caused by two different constitutional structural anomalies involving chromosome 8, and possibly leading to the disorder due to effects on the RUNX1T1 gene, which was hypo-expressed and hyper-expressed, respectively, in the two patients. The chromosome change was unbalanced in one patient, and balanced in the other one. Conclusions: We analyzed the sequence of events in the pathogenesis of the disease in the two patients, including a number of non-haematological signs present in the one with the unbalanced anomaly. We demonstrated that in these two patients the primary event causing BMFS/AA was the constitutional chromosome anomaly. If we take into account the cohort of 219 patients with a similar diagnosis in whom we made cytogenetic studies in the years 2003-2017, we conclude that cytogenetic investigations were instrumental to reach a diagnosis in 52 of them. We postulate that a chromosome change is the primary cause of BMFS/AA in a not negligible proportion of cases, as it was ascertained in 6 of these patients
PACSIN2 rs2413739 influence on thiopurine pharmacokinetics: validation studies in pediatric patients
Celestial Mechanics, Conformal Structures, and Gravitational Waves
The equations of motion for non-relativistic particles attracting
according to Newton's law are shown to correspond to the equations for null
geodesics in a -dimensional Lorentzian, Ricci-flat, spacetime with a
covariantly constant null vector. Such a spacetime admits a Bargmann structure
and corresponds physically to a generalized pp-wave. Bargmann electromagnetism
in five dimensions comprises the two Galilean electro-magnetic theories (Le
Bellac and L\'evy-Leblond). At the quantum level, the -body Schr\"odinger
equation retains the form of a massless wave equation. We exploit the conformal
symmetries of such spacetimes to discuss some properties of the Newtonian
-body problem: homographic solutions, the virial theorem, Kepler's third
law, the Lagrange-Laplace-Runge-Lenz vector arising from three conformal
Killing 2-tensors, and motions under inverse square law forces with a
gravitational constant varying inversely as time (Dirac). The latter
problem is reduced to one with time independent forces for a rescaled position
vector and a new time variable; this transformation (Vinti and Lynden-Bell)
arises from a conformal transformation preserving the Ricci-flatness
(Brinkmann). A Ricci-flat metric representing non-relativistic
gravitational dyons is also pointed out. Our results for general time-dependent
are applicable to the motion of point particles in an expanding
universe. Finally we extend these results to the quantum regime.Comment: 26 pages, LaTe
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