Cytopathologic features of adenoid cystic carcinoma. Case report and literature review.

A case of primary bronchial adenoid cystic carcinoma in a 40-year-old white female is reported. Cytologic findings in a bronchial wash specimen obtained at the time of bronchoscopic examination are described, with an emphasis on correlation with the histologic features of the tumor. The literature is briefly reviewed with respect to the occurrence of primary adenoid cystic carcinoma in the bronchial tree

The combined use of cytology and colposcopy in enhancing diagnostic accuracy in preclinical lesions of the uterine cervix.

In an attempt to evaluate the accuracy of cytologic and colposcopic findings (alone and in combination) in detecting preclinical lesions of the uterine cervix, diagnoses made in 170 consecutive patients referred for colposcopic examination at Nassau Hospital because of an abnormal Papanicolaou smear were reviewed. We found that of the investigative methods available prior to biopsy, a combined cytologic and colposcopic evaluation is preferred since it is highly accurate in predicting the degree of severity of a lesion (84.6% of all cases reviewed) and, in our experience, eliminates the problem of false negatives, which are encountered when either method is used to the exclusion of the other

Factors determining the degree of endometrial exfoliation and their diagnostic implications in endometrial adenocarcinoma.

Since the degree of endometrial exfoliation largely determines the ability of cytology to diagnose endometrial adenocarcinomas by the study of cervicovaginal smears, five features of their subsequent histologically diagnosed endometrial adenocarcinomas were studied in 28 patients whose smears contained endometrial cells. The surface area occupied by abnormal endometrium was found to be an important determinant in the degree of endometrial exfoliation. The tumor grade, endocervical involvement, pattern of growth and squamous-cell component were all factors that influenced cellular shedding. The extent of myometrial involvement did not affect the likelihood that an endometrial adenocarcinoma would be diagnosed cytologically prior to histologic examination