1,272 research outputs found
Children’s Moral and Affective Judgments Regarding Provocation and Retaliation
Moral judgments, attributions of emotion, and their associations were examined in hypothetical, prototypical situations and situations of provocation and peer retaliation. Eighty-one school-age children, 46 kindergartners and first graders and 35 2nd–4th graders, judged prototypical and provoked moral transgressions (hitting and teasing). Children judged hypothetical moral transgressions to be more serious and more deserving of punishment, and they reasoned more about concerns with others’ welfare, for prototypical than for provoked transgressions and when retaliation involved hitting rather than teasing. Children’s moral condemnation of provocation increased with age. Across conditions, children attributed greater happiness to transgressors than to victims; “happy victimizer” responses decreased with age for prototypical but not for provoked transgressions. Moreover, retaliators were seen as both happier and angrier than their victims. Anger increased and sadness decreased with age, but children’s emotion attributions were not associated with their moral judgments about either prototypical or provoked transgressions
Pharmacologic Treatment for Pediatric Gastroparesis: A Review of the Literature
There have been a number of agents that have been tried for treatment of gastroparesis over the past 3 decades, with varying levels of success. Guidelines exist for the management of gastroparesis in adults; however, even though the cause of gastroparesis in children is similar to that in adults, no guidelines exist for treating pediatric gastroparesis as studies on the topic are limited. With what little information we have on pediatric gastroparesis, medications used in children's studies do not seem to demonstrate the same results as in adult patients with gastroparesis; thus, future studies of whether certain medications are effective for treating pediatric gastroparesis and at what dose still need to be conducted. Pharmacological treatment options for pediatric gastroparesis do not show a clear correlation of resolving or even maintaining gastroparesis-associated symptoms or disease state. This article reviews the available studies of drugs that have shown some efficacy, with an emphasis on pediatric studies
Magnetocardiography with a modular spin-exchange relaxation free atomic magnetometer array
We present a portable four-channel atomic magnetometer array operating in the
spin exchange relaxation-free regime. The magnetometer array has several design
features intended to maximize its suitability for biomagnetic measurement,
specifically foetal magnetocardiography, such as a compact modular design, and
fibre coupled lasers. The modular design allows the independent positioning and
orientation of each magnetometer, in principle allowing for non-planar array
geometries. Using this array in a magnetically shielded room, we acquire adult
magnetocadiograms. These measurements were taken with a 6-11 fT Hz^(-1/2)
single-channel baseline sensitivity that is consistent with the independently
measured noise level of the magnetically shielded room.Comment: 15 pages, 5 figure
Physiologic heart rate dependency of the PQ interval and its sex differences
On standard electrocardiogram (ECG) PQ interval is known to be moderately heart rate dependent, but no physiologic details of this dependency have been established. At the same time, PQ dynamics is a clear candidate for non-invasive assessment of atrial abnormalities including the risk of atrial fibrillation. We studied PQ heart rate dependency in 599 healthy subjects (aged 33.5 ± 9.3 years, 288 females) in whom drug-free day-time 12-lead ECG Holters were available. Of these, 752,517 ECG samples were selected (1256 ± 244 per subject) to measure PQ and QT intervals and P wave durations. For each measured ECG sample, 5-minute history of preceding cardiac cycles was also obtained. Although less rate dependent than the QT intervals (36 ± 19% of linear slopes), PQ intervals were found to be dependent on underlying cycle length in a highly curvilinear fashion with the dependency significantly more curved in females compared to males. The PQ interval also responded to the heart rate changes with a delay which was highly sex dependent (95% adaptation in females and males after 114.9 ± 81.1 vs 65.4 ± 64.3 seconds, respectively, p < 0.00001). P wave duration was even less rate dependent than the PQ interval (9 ± 10% of linear QT/RR slopes). Rate corrected P wave duration was marginally but significantly shorter in females than in males (106.8 ± 8.4 vs 110.2 ± 7.9 ms, p < 0.00001). In addition to establishing physiologic standards, the study suggests that the curvatures and adaptation delay of the PQ/cycle-length dependency should be included in future non-invasive studies of atrial depolarizations
Short-term beat-to-beat QT variability appears influenced more strongly by recording quality than by beat-to-beat RR variability.
Increases in beat-to-beat variability of electrocardiographic QT interval duration have repeatedly been associated with increased risk of cardiovascular events and complications. The measurements of QT variability are frequently normalized for the underlying RR interval variability. Such normalization supports the concept of the so-called immediate RR effect which relates each QT interval to the preceding RR interval. The validity of this concept was investigated in the present study together with the analysis of the influence of electrocardiographic morphological stability on QT variability measurements. The analyses involved QT and RR measurements in 6,114,562 individual beats of 642,708 separate 10-s ECG samples recorded in 523 healthy volunteers (259 females). Only beats with high morphology correlation (r > 0.99) with representative waveforms of the 10-s ECG samples were analyzed, assuring that only good quality recordings were included. In addition to these high correlations, SDs of the ECG signal difference between representative waveforms and individual beats expressed morphological instability and ECG noise. In the intra-subject analyses of both individual beats and of 10-s averages, QT interval variability was substantially more strongly related to the ECG noise than to the underlying RR variability. In approximately one-third of the analyzed ECG beats, the prolongation or shortening of the preceding RR interval was followed by the opposite change of the QT interval. In linear regression analyses, underlying RR variability within each 10-s ECG sample explained only 5.7 and 11.1% of QT interval variability in females and males, respectively. On the contrary, the underlying ECG noise contents of the 10-s samples explained 56.5 and 60.1% of the QT interval variability in females and males, respectively. The study concludes that the concept of stable and uniform immediate RR interval effect on the duration of subsequent QT interval duration is highly questionable. Even if only stable beat-to-beat measurements of QT interval are used, the QT interval variability is still substantially influenced by morphological variability and noise pollution of the source ECG recordings. Even when good quality recordings are used, noise contents of the electrocardiograms should be objectively examined in future studies of QT interval variability
Moral dilemmas and abortion decision-making: Lessons learnt from abortion research in England and Wales
This paper scrutinises the concepts of moral reasoning and personal reasoning, problematising the binary model by looking at young women's pregnancy decision-making. Data from two UK empirical studies are subjected to theoretically driven qualitative secondary analysis, and illustrative cases show how complex decision-making is characterised by an intertwining of the personal and the moral, and is thus best understood by drawing on moral relativism
Beliefs about the permissibility of abortion and their relationship to decisions regarding abortion
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/43494/1/11111_2004_Article_BF00972499.pd
On the nucleolar and cytoplasmic RNA density during "cell dedifferentiation" represented by blastic transformation of human mature T lymphocytes - a cytochemical study.
Exploring the Role of Practical Wisdom in Addressing Adolescent Childrearing Dilemmas
Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/154376/1/fare12400.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/154376/2/fare12400_am.pd
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