Production planning in flexible manufacturing systems using an expert system

This paper deals with generating a near optimal production plan for Flexible Manufacturing Systems (FMS). The production plan is one of the most important aspects for the efficient operation of FMS. First, we define the scope of the production planning problem. Then we develop a set of production rules to be used in an expert system approach to the problem. The expert system has been implemented in Guru 2.0, an expert system development tool. The performance of this expert system is evaluated using a set of small to medium-size problem data. Based on the test results, the expert system approach to the solution of the production planning problem appears to be an efficient method

Higgs decay into four charged leptons in the presence of dimension-six operators

We study the indirect effects of New Physics in the Higgs decay into four charged leptons, using an Effective Field Theory (EFT) approach to Higgs interactions. We evaluate the deviations induced by the EFT dimension-six operators in observables like partial decay width and various kinematic distributions, including angular observables, and compare them with the contribution of the full SM electroweak corrections. The calculation is implemented in an improved version of the event generator Hto4l, which can provide predictions in terms of different EFT-bases and is available for data analysis at the LHC. We also perform a phenomenological study in order to assess the benefits coming from the inclusion of differential information in the future analyses of very precise data which will be collected during the high luminosity phase of the LHC.Comment: 31 pages, 8 figures, 1 table. Version to appear on JHEP, expanded phenomenological section including an analysis for HL-LH

Subjugation and Transformation of the Major Female Character in Chetan Bhagat’s One Indian Girl

Chetan Bhagat is a popular Indian writer. He exposes the various issues being practiced in society. All his novels present the problems of youths, their hopes, aspirations, dreams and frustrations. The Present novel One Indian Girl is acclaimed for his stance on female issues. This novel is presented from the female perspective. Radhika is the major female character in the fiction. She is victim of the male chauvinism. She undergoes many tribulations but in the end she takes her own decision. She doesn’t accept the male choice. After much emphasis she accepts to do arrange marriage but at the she realizes her own importance and refuses to marry. She determines to live life according to her own terms. The writer presents her expedition in a fantastic way

MENTHA PIPERITA LINN: PHYTOCHEMICAL, ANTIBACTERIAL AND DIPTERIAN ADULTICIDAL APPROACH

Objective: There is an immense need to develop an alternative antimicrobial source for the treatment of several infectious diseases and restrict its vectors. So, evaluation of phytochemicals from Mentha piperita, its antibacterial and adulticidal potential was undertaken in the present study.Methods: The organic solvent of ethanol and water were used for the preparation of extract for the study. These extracts were analyzed for the qualitative and quantitative phytochemicals. Antimicrobial activity was determined by using agar well diffusion method, and Bioassay was carried out by "Sugar Bait" Method to check adulticidal potential. Results: The Mentha piperita were found a rich source of phytochemical compounds like diterpenes, steroids, tannin, flavonoids, cardial glycosides, alkaloids, phenols, coumarin, and saponin. Both the extracts possesses active antibacterial compounds which shown antibacterial activity. The aqueous (5% of 50 µl) and ethanolic (5% of 100 µl) extract (EA) were found as effective concentration. Salmonella typhimurium showed resistance against both the extracts. The aqueous extract (AE) has found with effective adulticidal potential. Hence it can be used to control and repel most popular disease spreading Dipterian vector, Musca domestica.Conclusion: These results confirm the presence of antibacterial, adulticidal compounds in Mentha piperita which gives an opportunity to explore the possible usage of Mentha piperita in the development of antibiotics and insecticides.Keywords: Mentha piperita L., Phytochemical analysis, Antibacterial, Adulticidal potentia

Design and Development of a Microwave Generated Lactose Monohydrate - Microcrystalline Cellulose Based Multifunctional Excipient Composites for Tablet Formulation using Box–Behnken Design

The concept of co-processing as a particle engineering technique continues to be used as a tool to enhance the functionality of several existing excipients. This important research was designed to improve the functionality of lactose monohydrate as excipient for direct compression by co-processing with microcrystalline cellulose. Microwave induced diffusion technique was first utilized for manufacturing Co processed lactose monohydrate (LM) - microcrystalline cellulose (MC) composites. The objective of the research was to obtain synergistic effects, incorporating better tablet adherence and hardness capacity. Box-Behnken experimental design was worked out to optimize the proportion of the primary excipients for the co-processed excipient. Fifteen experiments were carried out to assess the effect of primary excipients and mixing time required to prepare a slurry for microwaving treatment on percent fines, angle of repose, Carr’s index, friability, tensile strength, disintegration time as responses. The combination of the co-processed excipient that constructed significant characteristics after optimization was observed to be 70 % alpha-Lactose-monohydrate and 30 % microcrystalline cellulose. Consequently, Microcrystalline Cellulose-Lactose composites (MCLM), a co-processed excipient, was developed that offers functionality for direct compression, as a result of given flowability and compactability. Solid-state characterization was performed on optimized composites to ascertain its particle size, shape, distribution, surface morphology, degree of crystallinity, hygroscopicity, compatibility etc. employing proven analytical methods. Powder characteristics were determined by bulk and tapped densities, angle of repose, porosity, lubricant sensitivity ratio, dilution potential etc. The compaction patterns of MCLM were assessed employing Heckel and Kawakita equations and the compressibility, tabletability, compactability (CTC) profile was determined compared to the physical mixture of the native excipients and Cellactose. Tablets were developed by direct compression using paracetamol as the drug of choice. The results imply that microwave generated MCLM composites offers improved properties in comparison with native MC and LM. The current study highlights the concept of microwave drying technique as a cost-effective means for manufacturing multifunctional directly compressible excipient in comparison to the spray-drying technique

Traumatic pseudoaneurysm of the superficial temporal artery

Pseudoaneurysm is deficit of all the 3 layers of the blood vessel. Superficial temporal artery due to its course is more prone for traumaand 95% of the pseudoaneurysm of the superficial artery is due to trauma. Here, we report the case of a traumatic pseudoaneurysm ofthe superficial temporal artery in a 19-year-old patient. The patient came with the complaints of swelling in the left side of the foreheadfor 3days and a history of trauma 3 days back by a cricket ball. A duplex scan showed a pseudoaneurysm of the superficial temporalartery. Surgical excision of the aneurysm was done after ligating proximal and distal pedicles. Digital subtraction angiography is thegold standard investigation, but duplex would be enough in most of the cases for diagnosingand surgical excision after ligating theproximal and distal pedicles is the treatment of choice

Novel Sorption Enhanced Reaction Process for Simultaneous Production of CO2 and H2 from Synthesis Gas Produced by Coal Gasification

The goal of this project is to evaluate the extensive feasibility of a novel concept called Thermal Swing Sorption Enhanced Reaction (TSSER) process to simultaneously produce H{sub 2} and CO{sub 2} as a single unit operation in a sorber-reactor. The successful demonstration of the potential feasibility of the TSSER concept implies that it is worth pursuing further development of the idea. This can be done by more extensive evaluation of the basic sorptive properties of the CO{sub 2} chemisorbents at realistic high pressures and by continuing the experimental and theoretical study of the TSSER process. This will allow us to substantiate the assumptions made during the preliminary design and evaluation of the process and firm up the initial conclusions. The task performed under this project consists of (i) retrofitting an existing single column sorption apparatus for measurement of high pressure CO{sub 2} sorption characteristics, (ii) measurement of high pressure CO{sub 2} chemisorption equilibria, kinetics and sorption-desorption column dynamic characteristics under the conditions of thermal swing operation of the TSSER process, (iii) experimental evaluation of the individual steps of the TSSER process (iv) development of extended mathematical model for simulating cyclic continuous operation of TSSER to aid in process scale-up and for guiding future work, (v) simulate and test SER concept using realistic syngas composition, (vi) extensive demonstration of the thermal stability of sorbents using a TGA apparatus, (vii) investigation of the surfaces of the adsorbents and adsorbed CO{sub 2} ,and (viii) test the effects of sulfur compounds found in syngas on the CO{sub 2} sorbents

Learning internal iliac artery ligation and pelvic ureter course through cadaveric dissections

Background: Few surgical procedures, although vital, are not learnt and mastered during postgraduate courses in Obstetrics and Gynecology. Internal iliac artery ligation and tracing course of ureter are few of such surgical procedures. Cadaveric dissection sessions organized during postgraduate courses and as CME sessions (continued medical education) have proved useful in learning such unlearnt procedures. This article shares experiences from teaching internal iliac artery ligation, pelvic ureter course tracing and principles of many other unusual gynaecological surgical procedures to Obstetrics and Gynecology specialists and postgraduate students through CME programs involving cadaveric dissection.Methods: This involved organizing and conducting four cadaveric dissection CME workshops at three different teaching institutions. The components of these CMEs were lectures with power point presentations and two-way audio-visual interactive sessions while pelvic anatomy was demonstrated on cadavers through live dissections. Each CME was concluded by tactile experience to each delegate by handling the dissected cadavers; this was made possible by limiting delegate registration to 50 at each CME.Results: The surgical skills of internal iliac artery ligation and tracing course of pelvic ureter, which are not adequately and confidently learnt in routine postgraduate tenure, could be effectively transferred through cadaveric dissection.Conclusions: Revisiting anatomy dissection halls helps in learning rare but lifesaving surgical techniques. This can be achieved by arranging cadaveric dissection CMEs for practicing specialists. Such CMEs should be organized regularly and should be integrated into postgraduate curriculum

Isolation and identification of Micrococcus roseus and Planococcus sp. from schirmacher oasis, Antarctica

Five cultures isolated from soil samples collected in Schirmacher oasis, Antarctica, have been identified as members of the family Micrococcaceae, with 3 belonging to the genusMicrococcus and two toPlanococcus. The 3 Micrococcus isolates (37R, 45R and 49R) were red-pigmented and h a d ~ 75 mol% G + C in their DNA; they were identified as Micrococcus roseus. The twoPlanococcus isolates (30Y and Lz3OR) were yellow and orange in colour, and had 43·5 and 40·9 mol % G + C in their DNA respectively; they were identified as Planococcus sp