2,576 research outputs found

    Policies for multinational corporations

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    Protectionism in EC-US trade relations

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    During the 1950s and early 1960s the trading interests of the US and the EC generally coincided, with the result that tariff negotiations could be held successfully. Since that time the interests of the US and the EC have diverged somewhat, and pressures for increased protection have arisen

    Identifications of Einstein Slew Survey sources

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    The status of identifications of the Einstien Slew Survey, a bright soft x-ray catalog with 550 new x-ray sources, is discussed. Possible counterparts were found for greater than 95 percent of the Slew Survey based on positional coincidences and color-color diagnostics. The survey will be fully identified via upcoming radio and optical observations

    Einstein Slew Survey: Data analysis innovations

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    Several new methods were needed in order to make the Einstein Slew X-ray Sky Survey. The innovations which enabled the Slew Survey to be done are summarized. These methods included experimental approach to large projects, parallel processing on a LAN, percolation source detection, minimum action identifications, and rapid dissemination of the whole data base

    Human pancreatic cancer cell lines do not express receptors for somatostatin.

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    The in vivo administration of somatostatin (SS) or its analogues is capable of suppressing the growth of pancreatic cancer in experimental animals. We examined the effects of SS-14 and its analogue RC-160 on the in vitro growth of two human pancreatic cancer cell lines MiaPaCa-2 and Panc-1 stimulated with epidermal growth factor (EGF) or insulin-like growth factor 1 (IGF-1). Neither SS-14 nor RC-160 inhibited the growth of either cell line. In contrast RC-160 did inhibit the EGF-stimulated growth of a rat pancreatic cancer cell line AR42J. Binding studies with 125I-Tyr11 somatostatin revealed the presence of a single class of high affinity binding sites with a Kd of 0.20 +/- 0.05 nM and a Bmax of 2.1 +/- 0.26 pmoles mg-1 protein on AR42J but not displaceable binding was observed on MiaPaCa-2 or Panc-1. We conclude that lack of receptors accounts for the failure of SS-14 and RC-160 to influence the growth of human pancreatic cancer in vitro. These results, taken together with other findings, lead us to question the therapeutic efficacy of somatostatin and its analogues as mono-therapy in the treatment of human pancreatic cancer

    Obscuration in the Host Galaxies of Soft X-ray Selected Seyferts

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    We define a new sample of 96 low-redshift (z<0.1), soft X-ray selected Seyferts from the catalog of the Einstein Slew Survey (Elvis etal. 1992, Plummer et al. 1994). We probe the geometry and column depth of obscuring material in the host-galaxy disks using galaxian axial ratios determined mainly from the Digitized Sky Survey. The distribution of host-galaxy axial ratios clearly shows a bias against edge-on spirals, confirming the existence of a geometrically thick layer of obscuring material in the host-galaxy planes. Soft X-ray selection recovers some of the edge-on objects missed in UV and visible surveys but still results in 30% incompleteness for Type 1's. We speculate that thick rings of obscuring material like the ones we infer for these Seyferts might be commonly present in early type spirals, sitting at the Inner Lindblad Resonances of the nonaxisymmetric potentials of the host galaxies.Comment: 14 pages including 2 tables and 3 eps figures, aas2pp4.sty, to appear in Ap

    Isolated Gallbladder Rupture Due to Blunt Abdominal Trauma

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    Traumatic injury to the extrahepatic biliary system is rare and usually diagnosed at laparotomy when it is associated with other visceral injuries. Isolated gallbladder rupture due to blunt abdominal trauma is even rarer. The clinical presentation of gallbladder injury is variable, resulting in a delay in diagnosis and treatment. Awareness to the possibilty of trauma to the extrahepatic biliary system enables early surgical intervention and eliminates the high morbidity associated with delated diagnosis

    Reinventing College Physics for Biologists: Explicating an epistemological curriculum

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    The University of Maryland Physics Education Research Group (UMd-PERG) carried out a five-year research project to rethink, observe, and reform introductory algebra-based (college) physics. This class is one of the Maryland Physics Department's large service courses, serving primarily life-science majors. After consultation with biologists, we re-focused the class on helping the students learn to think scientifically -- to build coherence, think in terms of mechanism, and to follow the implications of assumptions. We designed the course to tap into students' productive conceptual and epistemological resources, based on a theoretical framework from research on learning. The reformed class retains its traditional structure in terms of time and instructional personnel, but we modified existing best-practices curricular materials, including Peer Instruction, Interactive Lecture Demonstrations, and Tutorials. We provided class-controlled spaces for student collaboration, which allowed us to observe and record students learning directly. We also scanned all written homework and examinations, and we administered pre-post conceptual and epistemological surveys. The reformed class enhanced the strong gains on pre-post conceptual tests produced by the best-practices materials while obtaining unprecedented pre-post gains on epistemological surveys instead of the traditional losses.Comment: 35 pages including a 15 page appendix of supplementary material

    Wide band X-ray and optical observations of the BL Lac object 1ES 1959+650 in high state

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    The blazar 1ES 1959+650 was observed twice by BeppoSAX in September 2001 simultaneously with optical observations. We report here the X-ray data together with the optical, R_C magnitude, light curve since August 1995. The BeppoSAX observations were triggered by an active X-ray status of the source. The X-ray spectra are brighter than the previously published X-ray observations, although the source was in an even higher state a few months later, as monitored by the ASM onboard RossiXTE, when it was also detected to flare in the TeV band. Our X-ray spectra are well represented by a continuosly curved model up to 45 keV and are interpreted as synchrotron emission, with the peak moving to higher energies. This is also confirmed by the slope of the X-ray spectrum which is harder than in previous observations. Based on our optical and X-ray data, the synchrotron peak turns out to be in the range 0.1-0.7 keV. We compare our data with non simultaneous radio to TeV data and model the spectral energy distribution with a homogeneous, one-zone synchrotron inverse Compton model. We derive physical parameters that are typical of low power High Energy peaked Blazar, characterised by a relatively large beaming factor, low luminosity and absence of external seed photons.Comment: 12 pages, 6 figures, accepted by A&
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