36 research outputs found
Effect of alternative temozolomide schedules on glioblastoma O6-methylguanine-DNA methyltransferase activity and survival
Brief Report - Intraoperative high field magnetic resonance imaging in neurosurgery: Our initial experience with the brain suite
We present our initial experience with the high field (1.5T)
intra-operative magnetic resonance imaging, the operating room set-up,
our initial cases, the difficulties we faced and how this tool affected
a change in the surgical strategy intra-operatively and finally our
results. 11 patients were operated on from June 1st to August 1st 2006
of which there were astrocytomas (7), pituitary adenoma (1),
craniopharyngioma (1) and meningiomas (2) Localization and lesion
targeting were accurate, intra-operative imaging helped to assess the
resection volumes, enable corrections for brain shift, perform further
tumor resection at the same sitting and help preserve eloquent cortical
areas. Gliomas formed 63.6% of the tumors operated on and in 71.4% of
these, our surgical strategy changed intra-operatively. Meningiomas
formed 9.1% of the tumors operated and image guidance enabled a
minimally invasive approach, although no change in our surgical plan
was required. One pituitary adenoma and a craniopharyngioma were also
operated on with good outcome