Evaluation of the suitability of Skylab data for the purpose of petroleum exploration

There are no author-identified significant results in this report

An evaluation of the suitability of ERTS data for the purposes of petroleum exploration

This experiment was designed to determine the types and amounts of information valuable to petroleum exploration extractable from ERTS data and the cost of obtaining the information using traditional or conventional means. It was desired that an evaluation of this new petroleum exploration tool be made in a geologically well known area in order to assess its usefulness in an unknown area. The Anadarko Basin lies in western Oklahoma and the panhandle of Texas. It was chosen as a test site because there is a great deal of published information available on the surface and subsurface geology of the area, and there are many known structures that act as traps for hydrocarbons. This basin is similar to several other large epicontinental sedimentary basins. It was found that ERTS imagery is an excellent tool for reconnaissance exploration of large sedimentary basins or new exploration provinces. For the first time, small and medium size oil companies can rapidly and effectively analyze exploration provinces as a whole

Effects of a Pragmatic Home-based Exercise Program Concurrent With Neoadjuvant Therapy on Physical Function of Patients With Pancreatic Cancer: The PancFit Randomized Clinical Trial

OBJECTIVE: To determine the effects of a preoperative, home-based exercise program on fitness and physical function in patients with pancreatic cancer. BACKGROUND: We previously established a well-tolerated preoperative exercise program after finding a high frequency of sarcopenia and frailty in patients with pancreatic cancer. METHODS: In this randomized, controlled trial (NCT03187951), patients with pancreatic cancer were randomized to Arm A: enhanced usual care or Arm B: prescribed aerobic and resistance exercise during neoadjuvant therapy. Patients received nutrition counseling and activity trackers. The primary endpoint was 6-minute walk distance (6MWD; ≥14 meters improvement was clinically meaningful). Secondary endpoints included additional physical function tests, health-related quality of life, and clinical outcomes. RESULTS: One hundred fifty-one patients were randomized. Objectively measured weekly activity (153.2±135.6 and 159.8±122.8 min in Arm A and B, respectively, P =0.62) and self-reported weekly moderate-to-strenuous physical activity (107.4±160.4 and 129.6±161.6 min in Arm A and Arm B, respectively, P =0.49) were similar, but weekly strength training sessions increased more in Arm B (by 1.8±1.8 vs 0.1±2.4 sessions, P CONCLUSIONS: In this randomized trial of prescribed exercise versus enhanced usual care during neoadjuvant therapy for pancreatic cancer, a high volume of physical activity and increased exercise capacity were observed in both arms, highlighting the importance of activity among patients preparing for surgery

Investigation of possible aqueous phase formation during vaporization of sevoflurane

Background and Aims: Ultane®(sevoflurane; AbbVie Inc., North Chicago, IL, USA) has a dissolved water content of approximately 0.035% weight/weight (w/w). A previous report described formation of an aqueous layer in 4 of 13 sevoflurane vaporizers used in operating rooms. We investigated the conditions under which an aqueous layer could develop during vaporization of sevoflurane–water mixtures. Material and Methods: A temperature-controlled glass reactor was used to simulate a vaporizer. In four experiments, the vaporization of different sevoflurane–water mixtures was monitored over approximately 3–4 days. Samples were removed at regular intervals for analysis of water content. For confirmation, one experiment was replicated in a Tec 7 vaporizer. Results: Saturation of sevoflurane with water occurred at 0.11%–0.13% w/w at an ambient temperature; at greater water concentrations a separate aqueous phase was initially present. The sevoflurane–water azeotrope contained approximately 1.2% w/w water at 25°C. When the initial water content was <1.2% w/w (0.11%–1.03% w/w), vaporization resulted in a single phase of drier sevoflurane (final water concentration 0.02%–0.08% w/w). When the starting water concentration exceeded the azeotropic concentration (5.0% w/w), vaporization increased the water content, reaching 13% w/w at 71 h. Results under the low initial water condition were similar in the Tec 7 vaporizer. Conclusions: An increase in water concentration following vaporization of sevoflurane can only occur when the starting water content is higher than the azeotropic concentration and therefore cannot originate from the dissolved water present in the marketed product because the water concentration in Ultane®is 34 times lower than the azeotropic concentration