Localization phenomenon investigation on Smated stainless samples by speckle interferometry

In-plane Electronic Speckle Pattern Interferometry (ESPI) has been successfull y used during tensile tests on SMA-treated (Surface Mechanical Attrition Treatment) and as received 316L stainless steel in order to measure the strain rate field. The heterogeneity in the strain rate field can be observed from a stage of deformation which doesn’t coincide with the classic Considère’s criterion (dF=0) for the diffuse neck initiation (or plastic instability). The initiation of this heterogeneity strongly depends on treatments undergone by the material. In this paper, a comparison was performed about the heterogeneity initiation of specimens SMATed during 30 minutes with 2 mm shot, 3 mm shot and a non-treated sample. The formation of the two slip band system until fracture of the tensile specimen was also studied

Localization phenomenon investigation on Smated stainless samples by speckle interferometry

In-plane Electronic Speckle Pattern Interferometry (ESPI) has been successfull y used during tensile tests on SMA-treated (Surface Mechanical Attrition Treatment) and as received 316L stainless steel in order to measure the strain rate field. The heterogeneity in the strain rate field can be observed from a stage of deformation which doesn’t coincide with the classic Considère’s criterion (dF=0) for the diffuse neck initiation (or plastic instability). The initiation of this heterogeneity strongly depends on treatments undergone by the material. In this paper, a comparison was performed about the heterogeneity initiation of specimens SMATed during 30 minutes with 2 mm shot, 3 mm shot and a non-treated sample. The formation of the two slip band system until fracture of the tensile specimen was also studied

Docetaxel serum protein binding with high affinity to alpha 1-acid glycoprotein.

International audienceThe binding of docetaxel to human plasma proteins was studied by ultrafiltration at 37 degrees C and pH 7.4. Docetaxel was extensively (> 98%) plasma protein bound. At clinically relevant concentrations (1-5 micrograms/ml), the plasma binding was concentration-independent. Lipoproteins, alpha1-acid glycoprotein and albumin were the main carriers of docetaxel in plasma, and owing to the high interindividual variability of alpha1-acid glycoprotein plasma concentration, particularly in cancer, it was concluded that alpha1-acid glycoprotein should be the main determinant of docetaxel plasma binding variability. Drugs potentially coadministered with docetaxel (cisplatin, dexamethasone, doxorubicin, etoposide, vinblastine) did not modify the plasma binding of docetaxel. In blood, docetaxel was found to be mainly located in the plasma compartment (less than 15% associated to erythrocytes)

Multispectral Filters Assemblies for Earth Remote Sensing Imagers

International audienc