High scale mixing relations as a natural explanation for large neutrino mixing

The origin of small mixing among the quarks and a large mixing among the neutrinos has been an open question in particle physics. In order to answer this question, we postulate general relations among the quarks and the leptonic mixing angles at a high scale, which could be the scale of Grand Unified Theories. The central idea of these relations is that the quark and the leptonic mixing angles can be unified at some high scale either due to some quark-lepton symmetry or some other underlying mechanism and as a consequence, the mixing angles of the leptonic sector are proportional to that of the quark sector. We investigate the phenomenology of the possible relations where the leptonic mixing angles are proportional to the quark mixing angles at the unification scale by taking into account the latest experimental constraints from the neutrino sector. These relations are able to explain the pattern of leptonic mixing at the low scale and thereby hint that these relations could be possible signatures of a quark-lepton symmetry or some other underlying quark-lepton mixing unification mechanism at some high scale linked to Grand Unified Theories.Comment: 44 pages, several comments and three sub-sections are added for further clarificatio

Probability distributions for polymer translocation

We study the passage (translocation) of a self-avoiding polymer through a membrane pore in two dimensions. In particular, we numerically measure the probability distribution Q(T) of the translocation time T, and the distribution P(s,t) of the translocation coordinate s at various times t. When scaled with the mean translocation time , Q(T) becomes independent of polymer length, and decays exponentially for large T. The probability P(s,t) is well described by a Gaussian at short times, with a variance that grows sub-diffusively as t^{\alpha} with \alpha~0.8. For times exceeding , P(s,t) of the polymers that have not yet finished their translocation has a non-trivial stable shape.Comment: 5 pages, 4 figure

Material dependence of Casimir forces: gradient expansion beyond proximity

A widely used method for estimating Casimir interactions [H. B. G. Casimir, Proc. K. Ned. Akad. Wet. 51, 793 (1948)] between gently curved material surfaces at short distances is the proximity force approximation (PFA). While this approximation is asymptotically exact at vanishing separations, quantifying corrections to PFA has been notoriously difficult. Here we use a derivative expansion to compute the leading curvature correction to PFA for metals (gold) and insulators (SiO$_2$) at room temperature. We derive an explicit expression for the amplitude $\hat\theta_1$ of the PFA correction to the force gradient for axially symmetric surfaces. In the non-retarded limit, the corrections to the Casimir free energy are found to scale logarithmically with distance. For gold, $\hat\theta_1$ has an unusually large temperature dependence.Comment: 4 pages, 2 figure

Positive Feedback Regulation Results in Spatial Clustering and Fast Spreading of Active Signaling Molecules on a Cell Membrane

Positive feedback regulation is ubiquitous in cell signaling networks, often leading to binary outcomes in response to graded stimuli. However, the role of such feedbacks in clustering, and in spatial spreading of activated molecules, has come to be appreciated only recently. We focus on the latter, using a simple model developed in the context of Ras activation with competing negative and positive feedback mechanisms. We find that positive feedback, in the presence of slow diffusion, results in clustering of activated molecules on the plasma membrane, and rapid spatial spreading as the front of the cluster propagates with a constant velocity (dependent on the feedback strength). The advancing fronts of the clusters of the activated species are rough, with scaling consistent with the Kardar-Parisi-Zhang (KPZ) equation in one dimension. Our minimal model is general enough to describe signal transduction in a wide variety of biological networks where activity in the membrane-proximal region is subject to feedback regulation.Comment: 37 pages, 8 figures. Journal of Chemical Physics (in press

Casimir Force at a Knife's Edge

The Casimir force has been computed exactly for only a few simple geometries, such as infinite plates, cylinders, and spheres. We show that a parabolic cylinder, for which analytic solutions to the Helmholtz equation are available, is another case where such a calculation is possible. We compute the interaction energy of a parabolic cylinder and an infinite plate (both perfect mirrors), as a function of their separation and inclination, $H$ and $\theta$, and the cylinder's parabolic radius $R$. As $H/R\to 0$, the proximity force approximation becomes exact. The opposite limit of $R/H\to 0$ corresponds to a semi-infinite plate, where the effects of edge and inclination can be probed.Comment: 5 pages, 3 figures, uses RevTeX; v2: expanded conclusions; v3: fixed missing factor in Eq. (3) and incorrect diagram label (no changes to results); v4: fix similar factor in Eq. (16) (again no changes to results

The Unusual Universality of Branching Interfaces in Random Media

We study the criticality of a Potts interface by introducing a {\it froth} model which, unlike its SOS Ising counterpart, incorporates bubbles of different phases. The interface is fractal at the phase transition of a pure system. However, a position space approximation suggests that the probability of loop formation vanishes marginally at a transition dominated by {\it strong random bond disorder}. This implies a linear critical interface, and provides a mechanism for the conjectured equivalence of critical random Potts and Ising models.Comment: REVTEX, 13 pages, 3 Postscript figures appended using uufile

Polymer-mediated entropic forces between scale-free objects

The number of configurations of a polymer is reduced in the presence of a barrier or an obstacle. The resulting loss of entropy adds a repulsive component to other forces generated by interaction potentials. When the obstructions are scale invariant shapes (such as cones, wedges, lines or planes) the only relevant length scales are the polymer size R_0 and characteristic separations, severely constraining the functional form of entropic forces. Specifically, we consider a polymer (single strand or star) attached to the tip of a cone, at a separation h from a surface (or another cone). At close proximity, such that h<<R_0, separation is the only remaining relevant scale and the entropic force must take the form F=AkT/h. The amplitude A is universal, and can be related to exponents \eta governing the anomalous scaling of polymer correlations in the presence of obstacles. We use analytical, numerical and epsilon-expansion techniques to compute the exponent \eta for a polymer attached to the tip of the cone (with or without an additional plate or cone) for ideal and self-avoiding polymers. The entropic force is of the order of 0.1 pN at 0.1 micron for a single polymer, and can be increased for a star polymer.Comment: LaTeX, 15 pages, 4 eps figure

Spontaneous emission by rotating objects: A scattering approach

We study the quantum electrodynamics (QED) vacuum in the presence of a body rotating along its axis of symmetry and show that the object spontaneously emits energy if it is lossy. The radiated power is expressed as a general trace formula solely in terms of the scattering matrix, making an explicit connection to the conjecture of Zel'dovich [JETP Lett. 14, 180 (1971)] on rotating objects. We further show that a rotating body drags along nearby objects while making them spin parallel to its own rotation axis

QProber: A System for Automatic Classification of Hidden-Web Resources

The contents of many valuable web-accessible databases are only available through search interfaces and are hence invisible to traditional web "crawlers." Recently, commercial web sites have started to manually organize web-accessible databases into Yahoo!-like hierarchical classification schemes. Here, we introduce QProber, a modular system that automates this classification process by using a small number of query probes, generated by document classifiers. QProber can use a variety of types of classifiers to generate the probes. To classify a database, QProber does not retrieve or inspect any documents or pages from the database, but rather just exploits the number of matches that each query probe generates at the database in question. We have conducted an extensive experimental evaluation of QProber over collections of real documents, experimenting with different types of document classifiers and retrieval models. We have also tested our system with over one hundred web-accessible databases. Our experiments show that our system has low overhead and achieves high classification accuracy across a variety of databases