4,801 research outputs found
Model of Transcriptional Activation by MarA in Escherichia coli
We have developed a mathematical model of transcriptional activation by MarA
in Escherichia coli, and used the model to analyze measurements of
MarA-dependent activity of the marRAB, sodA, and micF promoters in mar-rob-
cells. The model rationalizes an unexpected poor correlation between the
mid-point of in vivo promoter activity profiles and in vitro equilibrium
constants for MarA binding to promoter sequences. Analysis of the promoter
activity data using the model yielded the following predictions regarding
activation mechanisms: (1) MarA activation of the marRAB, sodA, and micF
promoters involves a net acceleration of the kinetics of transitions after RNA
polymerase binding, up to and including promoter escape and message elongation;
(2) RNA polymerase binds to these promoters with nearly unit occupancy in the
absence of MarA, making recruitment of polymerase an insignificant factor in
activation of these promoters; and (3) instead of recruitment, activation of
the micF promoter might involve a repulsion of polymerase combined with a large
acceleration of the kinetics of polymerase activity. These predictions are
consistent with published chromatin immunoprecipitation assays of interactions
between polymerase and the E. coli chromosome. A lack of recruitment in
transcriptional activation represents an exception to the textbook description
of activation of bacterial sigma-70 promoters. However, use of accelerated
polymerase kinetics instead of recruitment might confer a competitive advantage
to E. coli by decreasing latency in gene regulation.Comment: 30 pages, 2 figure
The role of carbon for superconductivity in MgCNi from specific heat
The influence of carbon deficiency on superconductivity of MgCNi is
investigated by specific heat measurements in the normal and superconducting
state. In order to perform a detailed analysis of the normal state specific
heat, a computer code is developed which allows for an instantaneous estimate
of the main features of the lattice dynamics. By analyzing the evolution of the
lattice vibrations within the series and simultaneously considering the visible
mass enhancement, the loss in the electron-phonon coupling can be attributed to
significant changes of the prominent Ni vibrations. The present data well
supports the recently established picture of strong electron-phonon coupling
and ferromagnetic spin fluctuations in this compound.Comment: 4 pages, latex, corrections to the text, one reference added, one
figure correcte
Charmed Baryons with
The width of a recently discovered excited charmed-strange baryon, a
candidate for a state with spin 3/2, is calculated. In the absence of
configuration mixing between the ground-state (spin-1/2) charmed-strange baryon
and the spin-1/2 state lying about 95 MeV above it,
one finds and , where the tilde denotes the partial
width with kinematic factors removed. Assuming a kinematic factor for P-wave
decay of , one predicts MeV, while the channel is closed. Some
suggestions are given for detecting the , the spin-3/2 charmed
nonstrange baryon, and the , the spin-3/2 charmed doubly-strange
baryon.Comment: 11 pages, latex, 2 uuencoded figures sent separatel
Competition between the BCS superconductivity and ferromagnetic spin fluctuations in MgCNi
The low temperature specific heat of the superconductor MgCNi and a
non-superconductor MgCNi is investigated in detail. An additional
contribution is observed from the data of MgCNi but absent in
MgCNi, which is demonstrated to be insensitive to the applied
magnetic field even up to 12 Tesla. A detailed discussion on its origin is then
presented. By subtracting this additional contribution, the zero field specific
heat of MgCNi can be well described by the BCS theory with the gap ratio
() determined by the previous tunneling measurements. The
conventional s-wave pairing state is further proved by the magnetic field
dependence of the specific heat at low temperatures and the behavior of the
upper critical field.Comment: To appear in Physical Review B, 6 pages, 7 figure
Dilepton asymmetries at factories in search of transitions
In order to detect the possible presence of
amplitudes in neutral meson decays, we consider the measurement of decay
time asymmetries involving like-sign dilepton events at the factories.Comment: 5 pages, latex, no fig
Role of C in MgC_xNi_3 investigated from first principles
The influence of vacancies in the sub-lattice of , on its
structural, electronic and magnetic properties are studied by means of the
density-functional based Korringa-Kohn-Rostoker Green's function method
formulated in the atomic sphere approximation. Disorder is taken into account
by means of coherent-potential approximation. Characterizations representing
the change in the lattice properties include the variation in the equilibrium
lattice constants, bulk modulus and pressure derivative of the bulk modulus,
and that of electronic structure include the changes in the, total, partial and
-resolved density of states. The incipient magnetic properties are
studied by means of fixed-spin moment method of alloy theory, together in
conjunction with the phenomenological Ginzburg-Landau equation for magnetic
phase transition. The first-principles calculations reveal that due to the
breaking of the - bonds, some of the 3d states, which were lowered
in energy due to strong hybridization, are transfered back to higher energies
thereby increasing the itinerant character in the material. The Bloch spectral
densities evaluated at the high symmetry points however reveal that the charge
redistribution is not uniform over the cubic Brillouin zone, as new states are
seen to be created at the point, while a shift in the states on the
energy scale are seen at other high symmetry points
Superconductivity in SrFe_(2-x)Co_xAs_2: Internal Doping of the Iron Arsenide Layers
In the electron doped compounds SrFe_(2-x)Co_xAs_2 superconductivity with T_c
up to 20 K is observed for 0.2 < x < 0.4. Results of structure determination,
magnetic susceptibility, electrical resistivity, and specific heat are
reported. The observation of bulk superconductivity in all thermodynamic
properties -- despite strong disorder in the Fe-As layer -- favors an itinerant
picture in contrast to the cuprates and renders a p- or d-wave scenario
unlikely. DFT calculations find that the substitution of Fe by Co (x > 0.3)
leads to the suppression of the magnetic ordering present in SrFe_2As_2 due to
a rigid down-shift of the Fe-3d_(x^2-y^2) related band edge in the density of
states.Comment: 5 pages, 3 figure
Atomic Parity Violation and Precision Electroweak Physics - An Updated Analysis
A new analysis of parity violation in atomic cesium has led to the improved
value of the weak charge, . The implications
of this result for constraining the Peskin-Takeuchi parameters S and T and for
guiding searches for new Z bosons are discussed.Comment: 8 pages, LaTeX, 3 figures, Submitted to Physical Review D. Updated
experimental inputs and references; clarification of notatio
Triple product asymmetries in K, D_(s) and B_(s) decays
One distinguishes between "true" CP violating triple product (TP) asymmetries
which require no strong phases and "fake" asymmetries which are due to strong
phases but require no CP violation. So far a single true TP asymmetry has been
measured in . A general discussion is presented for
T-odd TP asymmetries in four-body decays. It is shown that TP asymmetries
vanish for two identical and kinematically indistinguishable particles in the
final state. Two examples are and . A non-zero TP asymmetry can be expected when non-trivial
kinematic correlations exist, as in the decay . Triple
product asymmetries measured in charmed particle decays indicate an interesting
pattern of final-state interactions. We reiterate a discussion of TP
asymmetries in meson decays to two vector mesons each decaying to a
pseudoscalar pair, extending results to decays where one vector meson decays
into a lepton pair. We derive expressions for time-dependent TP asymmetries for
neutral B decays to flavorless states in terms of the neutral mass
difference and the width-difference . Time-integrated
true CP violating asymmetries, measurable for untagged decays, are shown
to be suppressed by neither nor
if transversity amplitudes for CP-even and CP-odd states involve different weak
phases. In contrast, fake asymmetries require flavor tagging and are suppressed
by the former ratio when time-integrated. We apply our results to and data and suggest an application for .Comment: minor corrections, submitted to Phys. Rev.
Field-induced gapless electron pocket in the superconducting vortex phase of YNi2B2C as probed by magnetoacoustic quantum oscillations
By use of ultrasound studies we resolved magneto-acoustic quantum oscillation
deep into the mixed state of the multiband nonmagnetic superconductor YNi2B2C.
Below the upper critical field, only a very weak additional damping appears
that can be well explained by the field inhomogeneity caused by the flux-line
lattice in the mixed state. This is clear evidence for no or a vanishingly
small gap for one of the bands, namely, the spheroidal alpha band. This
contrasts de Haas--van Alphen data obtained by use of torque magnetometry for
the same sample, with a rapidly vanishing oscillation signal in the mixed
state. This points to a strongly distorted flux-line lattice in the latter case
that, in general, can hamper a reliable extraction of gap parameters by use of
such techniques.Comment: 6 pages, 6 figure
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