4,801 research outputs found

    Model of Transcriptional Activation by MarA in Escherichia coli

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    We have developed a mathematical model of transcriptional activation by MarA in Escherichia coli, and used the model to analyze measurements of MarA-dependent activity of the marRAB, sodA, and micF promoters in mar-rob- cells. The model rationalizes an unexpected poor correlation between the mid-point of in vivo promoter activity profiles and in vitro equilibrium constants for MarA binding to promoter sequences. Analysis of the promoter activity data using the model yielded the following predictions regarding activation mechanisms: (1) MarA activation of the marRAB, sodA, and micF promoters involves a net acceleration of the kinetics of transitions after RNA polymerase binding, up to and including promoter escape and message elongation; (2) RNA polymerase binds to these promoters with nearly unit occupancy in the absence of MarA, making recruitment of polymerase an insignificant factor in activation of these promoters; and (3) instead of recruitment, activation of the micF promoter might involve a repulsion of polymerase combined with a large acceleration of the kinetics of polymerase activity. These predictions are consistent with published chromatin immunoprecipitation assays of interactions between polymerase and the E. coli chromosome. A lack of recruitment in transcriptional activation represents an exception to the textbook description of activation of bacterial sigma-70 promoters. However, use of accelerated polymerase kinetics instead of recruitment might confer a competitive advantage to E. coli by decreasing latency in gene regulation.Comment: 30 pages, 2 figure

    The role of carbon for superconductivity in MgCx_{x}Ni3_{3} from specific heat

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    The influence of carbon deficiency on superconductivity of MgCNi3_{3} is investigated by specific heat measurements in the normal and superconducting state. In order to perform a detailed analysis of the normal state specific heat, a computer code is developed which allows for an instantaneous estimate of the main features of the lattice dynamics. By analyzing the evolution of the lattice vibrations within the series and simultaneously considering the visible mass enhancement, the loss in the electron-phonon coupling can be attributed to significant changes of the prominent Ni vibrations. The present data well supports the recently established picture of strong electron-phonon coupling and ferromagnetic spin fluctuations in this compound.Comment: 4 pages, latex, corrections to the text, one reference added, one figure correcte

    Charmed Baryons with J=3/2J = 3/2

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    The width of a recently discovered excited charmed-strange baryon, a candidate for a state Ξc\Xi_c^* with spin 3/2, is calculated. In the absence of configuration mixing between the ground-state (spin-1/2) charmed-strange baryon Ξc(a)\Xi_c^{(a)} and the spin-1/2 state Ξc(s)\Xi_c^{(s)} lying about 95 MeV above it, one finds Γ~(ΞcΞc(a)π)=(3/4)Γ~(ΞΞπ)\tilde \Gamma(\Xi^*_c \to \Xi_c^{(a)} \pi) = (3/4) \tilde \Gamma(\Xi^* \to \Xi \pi) and Γ~(ΞcΞc(s)π)=(1/4)Γ~(ΞΞπ)\tilde \Gamma(\Xi^*_c \to \Xi_c^{(s)} \pi) = (1/4) \tilde \Gamma(\Xi^* \to \Xi \pi), where the tilde denotes the partial width with kinematic factors removed. Assuming a kinematic factor for P-wave decay of pcm3p_{\rm cm}^3, one predicts Γ(ΞcΞc(a)π)=2.3\Gamma(\Xi^*_c \to \Xi_c^{(a)} \pi) = 2.3 MeV, while the ΞcΞc(s)π\Xi^*_c \to \Xi_c^{(s)} \pi channel is closed. Some suggestions are given for detecting the Σc\Sigma_c^*, the spin-3/2 charmed nonstrange baryon, and the Ωc\Omega_c^*, the spin-3/2 charmed doubly-strange baryon.Comment: 11 pages, latex, 2 uuencoded figures sent separatel

    Competition between the BCS superconductivity and ferromagnetic spin fluctuations in MgCNi3_3

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    The low temperature specific heat of the superconductor MgCNi3_3 and a non-superconductor MgC0.85_{0.85}Ni3_3 is investigated in detail. An additional contribution is observed from the data of MgCNi3_3 but absent in MgC0.85_{0.85}Ni3_3, which is demonstrated to be insensitive to the applied magnetic field even up to 12 Tesla. A detailed discussion on its origin is then presented. By subtracting this additional contribution, the zero field specific heat of MgCNi3_3 can be well described by the BCS theory with the gap ratio (Δ/kBTc\Delta/k_BT_c) determined by the previous tunneling measurements. The conventional s-wave pairing state is further proved by the magnetic field dependence of the specific heat at low temperatures and the behavior of the upper critical field.Comment: To appear in Physical Review B, 6 pages, 7 figure

    Dilepton asymmetries at BB factories in search of ΔB=ΔQ\Delta B =- \Delta Q transitions

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    In order to detect the possible presence of ΔB=ΔQ\Delta B = - \Delta Q amplitudes in neutral BB meson decays, we consider the measurement of decay time asymmetries involving like-sign dilepton events at the BB factories.Comment: 5 pages, latex, no fig

    Role of C in MgC_xNi_3 investigated from first principles

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    The influence of vacancies in the CC sub-lattice of MgCNi3MgCNi_{3}, on its structural, electronic and magnetic properties are studied by means of the density-functional based Korringa-Kohn-Rostoker Green's function method formulated in the atomic sphere approximation. Disorder is taken into account by means of coherent-potential approximation. Characterizations representing the change in the lattice properties include the variation in the equilibrium lattice constants, bulk modulus and pressure derivative of the bulk modulus, and that of electronic structure include the changes in the, total, partial and k\mathbf{k}-resolved density of states. The incipient magnetic properties are studied by means of fixed-spin moment method of alloy theory, together in conjunction with the phenomenological Ginzburg-Landau equation for magnetic phase transition. The first-principles calculations reveal that due to the breaking of the CC-NiNi bonds, some of the NiNi 3d states, which were lowered in energy due to strong hybridization, are transfered back to higher energies thereby increasing the itinerant character in the material. The Bloch spectral densities evaluated at the high symmetry points however reveal that the charge redistribution is not uniform over the cubic Brillouin zone, as new states are seen to be created at the Γ\Gamma point, while a shift in the states on the energy scale are seen at other high symmetry points

    Superconductivity in SrFe_(2-x)Co_xAs_2: Internal Doping of the Iron Arsenide Layers

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    In the electron doped compounds SrFe_(2-x)Co_xAs_2 superconductivity with T_c up to 20 K is observed for 0.2 < x < 0.4. Results of structure determination, magnetic susceptibility, electrical resistivity, and specific heat are reported. The observation of bulk superconductivity in all thermodynamic properties -- despite strong disorder in the Fe-As layer -- favors an itinerant picture in contrast to the cuprates and renders a p- or d-wave scenario unlikely. DFT calculations find that the substitution of Fe by Co (x > 0.3) leads to the suppression of the magnetic ordering present in SrFe_2As_2 due to a rigid down-shift of the Fe-3d_(x^2-y^2) related band edge in the density of states.Comment: 5 pages, 3 figure

    Atomic Parity Violation and Precision Electroweak Physics - An Updated Analysis

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    A new analysis of parity violation in atomic cesium has led to the improved value of the weak charge, QW(Cs)=72.06±0.46Q_W({\rm Cs}) = -72.06 \pm 0.46. The implications of this result for constraining the Peskin-Takeuchi parameters S and T and for guiding searches for new Z bosons are discussed.Comment: 8 pages, LaTeX, 3 figures, Submitted to Physical Review D. Updated experimental inputs and references; clarification of notatio

    Triple product asymmetries in K, D_(s) and B_(s) decays

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    One distinguishes between "true" CP violating triple product (TP) asymmetries which require no strong phases and "fake" asymmetries which are due to strong phases but require no CP violation. So far a single true TP asymmetry has been measured in KLπ+πe+eK_L\to \pi^+\pi^- e^+e^-. A general discussion is presented for T-odd TP asymmetries in four-body decays. It is shown that TP asymmetries vanish for two identical and kinematically indistinguishable particles in the final state. Two examples are D0Kπ+ππ+D^0\to K^-\pi^+\pi^-\pi^+ and D+Kπ+π+π0D^+\to K^-\pi^+\pi^+\pi^0. A non-zero TP asymmetry can be expected when non-trivial kinematic correlations exist, as in the decay KLe+ee+eK_L \to e^+ e^- e^+ e^-. Triple product asymmetries measured in charmed particle decays indicate an interesting pattern of final-state interactions. We reiterate a discussion of TP asymmetries in BB meson decays to two vector mesons each decaying to a pseudoscalar pair, extending results to decays where one vector meson decays into a lepton pair. We derive expressions for time-dependent TP asymmetries for neutral B decays to flavorless states in terms of the neutral BB mass difference Δm\Delta m and the width-difference ΔΓ\Delta\Gamma. Time-integrated true CP violating asymmetries, measurable for untagged BsB_s decays, are shown to be suppressed by neither Γs/Δms\Gamma_s/\Delta m_s nor ΔΓs/Γs\Delta\Gamma_s/\Gamma_s if transversity amplitudes for CP-even and CP-odd states involve different weak phases. In contrast, fake asymmetries require flavor tagging and are suppressed by the former ratio when time-integrated. We apply our results to BKϕB\to K^*\phi and BsϕϕB_s\to\phi\phi data and suggest an application for BsJ/ψϕB_s\to J/\psi\phi.Comment: minor corrections, submitted to Phys. Rev.

    Field-induced gapless electron pocket in the superconducting vortex phase of YNi2B2C as probed by magnetoacoustic quantum oscillations

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    By use of ultrasound studies we resolved magneto-acoustic quantum oscillation deep into the mixed state of the multiband nonmagnetic superconductor YNi2B2C. Below the upper critical field, only a very weak additional damping appears that can be well explained by the field inhomogeneity caused by the flux-line lattice in the mixed state. This is clear evidence for no or a vanishingly small gap for one of the bands, namely, the spheroidal alpha band. This contrasts de Haas--van Alphen data obtained by use of torque magnetometry for the same sample, with a rapidly vanishing oscillation signal in the mixed state. This points to a strongly distorted flux-line lattice in the latter case that, in general, can hamper a reliable extraction of gap parameters by use of such techniques.Comment: 6 pages, 6 figure
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