251 research outputs found

    EDBL: a General Lexical Basis for the Automatic Processing of Basque

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    EDBL (Euskararen Datu-Base Lexikala) is a general-purpose lexical database used in Basque text-processing tasks. It is a large repository of lexical knowledge (currently around 80,000 entries) that acts as basis and support in a number of different NLP tasks, thus providing lexical information for several language tools: morphological analysis, spell checking and correction, lemmatization and tagging, syntactic analysis, and so on. It has been designed to be neutral in relation to the different linguistic formalisms, and flexible and open enough to accept new types of information. A browser-based user interface makes the job of consulting the database, correcting and updating entries, adding new ones, etc. easy to the lexicographer. The paper presents the conceptual schema and the main features of the database, along with some problems encountered in its design and implementation in a commercial DBMS. Given the diversity of the lexical entities and the complex relationships existing among them, three total specializations have been defined under the main class of the hierarchy that represents the conceptual schema. The first one divides all the entries in EDBL into Basque standard and non-standard entries. The second divides the units in the database into dictionary entries (classified into the different parts-of-speech) and other entries (mainly non-independent morphemes and irregularly inflected forms). Finally, another total specialization has been established between single-word entries and multiword lexical units; this permits us to describe the morphotactics of single-word entries, and the constitution and surface realization schemas of multiword lexical units.A hierarchy of typed feature structures (FS) has been designed to map the entities and relationships in the database conceptual schema. The FSs are coded in TEI-conformant SGML, and Feature Structure Declarations (FSD) have been made for all the types of the hierarchy. Feature structures are used as a delivery format to export the lexical information from the database. The information coded in this way is subsequently used as input by the different language analysis tools

    Toxicological Findings of Self-Poisoning Suicidal Deaths: A Systematic Review by Countries

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    The use of illicit and non-illicit substances is widespread in suicides. The toxicological data may help in understanding the mechanism of death. This systematic review aimed to analyze autopsies related to suicides by consuming poison, focusing on the correlation between substance use and the country of origin to create an alarm bell to indicate that suicide maybe attempted and prevent it. The systematic review was conducted according to the PRISMA guidelines, with the primary objective of identifying autopsies conducted in cases of suicide by consuming poison in specific geographic areas. Significant differences in substances were observed between low-income and Western countries that confirm previous literature data. In rural areas and Asian countries, most suicides by consuming poison involve the use of pesticides, such as organophosphates and carbamates. In Western countries, illicit drugs and medically prescribed drugs are the leading cause of suicide by self-poisoning. Future research should shed light on the correlation between social, medical, and demographic characteristics and the autopsy findings in suicides by self-poisoning to highlight the risk factors and implement tailored prevention programs worldwide. Performing a complete autopsy on a suspected suicide by self-poisoning could be essential in supporting worldwide public health measures and policy makers. Therefore, complete autopsies in such cases must be vigorously promoted

    Therapeutic molecules for osteoarthritis treatment. role of phloretin, ipriflavone and raloxifene in lipopolysaccharide induced osteoarthritic chondrocytes

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    Purpose: The search of novel molecules for the treatment of osteoarthritis (OA) is complex as any new therapeutic approach should encompass these requirements: inhibition of cartilage degradation, protection of bone and inhibition of inflammation. In the last years, different drugs have been proposed though most of them did not succeed in fulfil these requirements. Moreover, few of them have been encapsulated in drug delivery systems to improve their therapeutic potential to achieve a sustained or controlled release compared to the administration of equivalent doses of the free compounds. Nanoscience has arisen in the last decades as a potential field of study in drug delivery because nanomaterials may overcome the main current limitations to achieve an efficient and localized drug delivery by improving the targeted delivery and providing a sustained or controlled delivery to prolong the therapeutic effect. On the other hand, different polyphenols and aromatic organic compounds are known to possess anti-inflammatory, antioxidant and bone density-building properties..
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