Inhibition of 11βHSD1 with the S-phenylethylaminothiazolone BVT116429 increases adiponectin concentrations and improves glucose homeostasis in diabetic KKAmice-5

immunoblot showing the changes of the different adiponectin forms. Several independent analyses were performed giving similar results. The two main adiponectin complexes, HMW and MMW bands, are indicated by arrows and molecular mass markers are shown.<p><b>Copyright information:</b></p><p>Taken from "Inhibition of 11βHSD1 with the S-phenylethylaminothiazolone BVT116429 increases adiponectin concentrations and improves glucose homeostasis in diabetic KKAmice"</p><p>http://www.biomedcentral.com/1471-2210/8/3</p><p>BMC Pharmacology 2008;8():3-3.</p><p>Published online 12 Feb 2008</p><p>PMCID:PMC2270815.</p><p></p

Inhibition of 11βHSD1 with the S-phenylethylaminothiazolone BVT116429 increases adiponectin concentrations and improves glucose homeostasis in diabetic KKAmice-4

squares) or rosiglitazone (white triangles) on plasma adiponectin. * < 0.05, ** < 0.01 when compared with vehicle.<p><b>Copyright information:</b></p><p>Taken from "Inhibition of 11βHSD1 with the S-phenylethylaminothiazolone BVT116429 increases adiponectin concentrations and improves glucose homeostasis in diabetic KKAmice"</p><p>http://www.biomedcentral.com/1471-2210/8/3</p><p>BMC Pharmacology 2008;8():3-3.</p><p>Published online 12 Feb 2008</p><p>PMCID:PMC2270815.</p><p></p

Inhibition of 11βHSD1 with the S-phenylethylaminothiazolone BVT116429 increases adiponectin concentrations and improves glucose homeostasis in diabetic KKAmice-10

from the cell supernatants. Data are means of triplicate determinations with standard deviations indicated. The solid line is a fit of the data to the same equation as in Fig 2.<p><b>Copyright information:</b></p><p>Taken from "Inhibition of 11βHSD1 with the S-phenylethylaminothiazolone BVT116429 increases adiponectin concentrations and improves glucose homeostasis in diabetic KKAmice"</p><p>http://www.biomedcentral.com/1471-2210/8/3</p><p>BMC Pharmacology 2008;8():3-3.</p><p>Published online 12 Feb 2008</p><p>PMCID:PMC2270815.</p><p></p

Inhibition of 11βHSD1 with the S-phenylethylaminothiazolone BVT116429 increases adiponectin concentrations and improves glucose homeostasis in diabetic KKAmice-9

Hibited value and s the slope factor.<p><b>Copyright information:</b></p><p>Taken from "Inhibition of 11βHSD1 with the S-phenylethylaminothiazolone BVT116429 increases adiponectin concentrations and improves glucose homeostasis in diabetic KKAmice"</p><p>http://www.biomedcentral.com/1471-2210/8/3</p><p>BMC Pharmacology 2008;8():3-3.</p><p>Published online 12 Feb 2008</p><p>PMCID:PMC2270815.</p><p></p

Inhibition of 11βHSD1 with the S-phenylethylaminothiazolone BVT116429 increases adiponectin concentrations and improves glucose homeostasis in diabetic KKAmice-3

squares) or rosiglitazone (white triangles) on plasma glucose. *< 0.05 and **< 0.01 when compared with vehicle.<p><b>Copyright information:</b></p><p>Taken from "Inhibition of 11βHSD1 with the S-phenylethylaminothiazolone BVT116429 increases adiponectin concentrations and improves glucose homeostasis in diabetic KKAmice"</p><p>http://www.biomedcentral.com/1471-2210/8/3</p><p>BMC Pharmacology 2008;8():3-3.</p><p>Published online 12 Feb 2008</p><p>PMCID:PMC2270815.</p><p></p

Inhibition of 11βHSD1 with the S-phenylethylaminothiazolone BVT116429 increases adiponectin concentrations and improves glucose homeostasis in diabetic KKAmice-7

Itazone (white triangles) for 8 days and plasma adiponectin and HbA1c were measured. * < 0.05, ** < 0.01, *** < 0.001 versus vehicle, n = 9 per group.<p><b>Copyright information:</b></p><p>Taken from "Inhibition of 11βHSD1 with the S-phenylethylaminothiazolone BVT116429 increases adiponectin concentrations and improves glucose homeostasis in diabetic KKAmice"</p><p>http://www.biomedcentral.com/1471-2210/8/3</p><p>BMC Pharmacology 2008;8():3-3.</p><p>Published online 12 Feb 2008</p><p>PMCID:PMC2270815.</p><p></p

Inhibition of 11βHSD1 with the S-phenylethylaminothiazolone BVT116429 increases adiponectin concentrations and improves glucose homeostasis in diabetic KKAmice-6

Sulin (B) are shown in response to 2 g/kg of glucose. Data are expressed as means ± SEM.<p><b>Copyright information:</b></p><p>Taken from "Inhibition of 11βHSD1 with the S-phenylethylaminothiazolone BVT116429 increases adiponectin concentrations and improves glucose homeostasis in diabetic KKAmice"</p><p>http://www.biomedcentral.com/1471-2210/8/3</p><p>BMC Pharmacology 2008;8():3-3.</p><p>Published online 12 Feb 2008</p><p>PMCID:PMC2270815.</p><p></p

Inhibition of 11βHSD1 with the S-phenylethylaminothiazolone BVT116429 increases adiponectin concentrations and improves glucose homeostasis in diabetic KKAmice-1

Hibited value and s the slope factor.<p><b>Copyright information:</b></p><p>Taken from "Inhibition of 11βHSD1 with the S-phenylethylaminothiazolone BVT116429 increases adiponectin concentrations and improves glucose homeostasis in diabetic KKAmice"</p><p>http://www.biomedcentral.com/1471-2210/8/3</p><p>BMC Pharmacology 2008;8():3-3.</p><p>Published online 12 Feb 2008</p><p>PMCID:PMC2270815.</p><p></p