308 research outputs found
Public Sexology: Rezension zu "Kritische Sexualwissenschaft" von Volkmar Sigusch
Volkmar Sigusch: Kritische Sexualwissenschaft: Ein Fazit. Frankfurt am Main: Campus 2019. 978359351057
Measurement of Direct Photon Emission in K^+ -> pi^+ pi^0 gamma Decay
We have performed a measurement of the K^+ -> pi^+ pi^0 gamma decay and have
observed 2 X 10^4 events. The best fit to the decay spectrum gives a branching
ratio for direct photon emission of (4.7\pm0.8\pm0.3) X 10^{-6} in the pi^+
kinetic energy region of 55 to 90 MeV and requires no component due to
interference with inner bremsstrahlung.Comment: 9 pages, 3 figures. To be submitted to PR
Improved Measurement of the K+ to pi+ nu nubar Branching Ratio
An additional event near the upper kinematic limit for K+ to pi+ nu nubar has
been observed by Experiment E949 at Brookhaven National Laboratory. Combining
previously reported and new data, the branching ratio is B(K+ to pi+ nu nubar)=
1.47 (+1.30, - 0.89) x 10-10 based on three events observed in the pion
momentum region 211<P<229 MeV/c. At the measured central value of the branching
ratio, the additional event had a signal-to-background ratio of 0.9
Pericytes regulate vascular immune homeostasis in the CNS.
Pericytes regulate the development of organ-specific characteristics of the brain vasculature such as the blood-brain barrier (BBB) and astrocytic end-feet. Whether pericytes are involved in the control of leukocyte trafficking in the adult central nervous system (CNS), a process tightly regulated by CNS vasculature, remains elusive. Using adult pericyte-deficient mice (Pdgfb ret/ret ), we show that pericytes limit leukocyte infiltration into the CNS during homeostasis and autoimmune neuroinflammation. The permissiveness of the vasculature toward leukocyte trafficking in Pdgfb ret/ret mice inversely correlates with vessel pericyte coverage. Upon induction of experimental autoimmune encephalomyelitis (EAE), pericyte-deficient mice die of severe atypical EAE, which can be reversed with fingolimod, indicating that the mortality is due to the massive influx of immune cells into the brain. Additionally, administration of anti-VCAM-1 and anti-ICAM-1 antibodies reduces leukocyte infiltration and diminishes the severity of atypical EAE symptoms of Pdgfb ret/ret mice, indicating that the proinflammatory endothelium due to absence of pericytes facilitates exaggerated neuroinflammation. Furthermore, we show that the presence of myelin peptide-specific peripheral T cells in Pdgfb ret/ret ;2D2 tg mice leads to the development of spontaneous neurological symptoms paralleled by the massive influx of leukocytes into the brain. These findings indicate that intrinsic changes within brain vasculature can promote the development of a neuroinflammatory disorder
Further Evidence for the Decay K+ to pi+ neutrino-antineutrino
Additional evidence for the rare kaon decay K+ to pi+ neutrino-antineutrino
has been found in a new data set with comparable sensitivity to the previously
reported result. One new event was observed in the pion momentum region
examined, 211<P<229 MeV/c, bringing the total for the combined data set to two.
Including all data taken, the backgrounds were estimated to contribute 0.15 pm
0.05 events. The branching ratio is B=1.57^{+1.75}_{-0.82} 10^{-10}.Comment: 10 pages, 2 figure
Improved measurement of the K+->pi+nu(nu)over-bar branching ratio
An additional event near the upper kinematic limit for K+-->pi(+)nu(nu) over bar has been observed by experiment E949 at Brookhaven National Laboratory. Combining previously reported and new data, the branching ratio is B(K+-->pi(+)nu(nu) over bar)=(1.47(-0.89)(+1.30))x10(-10) based on three events observed in the pion momentum region 211<P<229 MeV/c. At the measured central value of the branching ratio, the additional event had a signal-to-background ratio of 0.9
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