Adhesive for polyester films cures at room temperature, has high initial tack

Quick room-temperature-cure adhesive bonds polyester-insulated flat electrical cables to metal surfaces and various other substrates. The bond strength of the adhesive may be considerably increased by first applying a commercially available polyamide primer to the polyester film

Shaking Up Traditional Training With Lynda.com

Supporting the diverse technology training needs on campus while resources continue to dwindle is a challenge many of us continue to tackle. Institutions from small liberal arts campuses to large research universities are providing individualized training and application support 24/7 by subscribing to the lynda.com Online Training Library(r) and marketing the service to various combinations of faculty, staff and students. As a supplemental service on most of our campuses, lynda.com has allowed us to extend support to those unable to attend live lab-based training, those who want advanced level training, those who want training on specialized applications, and those who want to learn applications that are not in high demand. The service also provides cost effective professional development opportunities for everyone on campus, from our own trainers and technology staff who are developing new workshops, learning new software versions or picking up new areas of expertise from project management to programming, to administrative and support staff who are trying to improve their skills in an ever-tighter economic environment. On this panel discussion, you will hear about different licensing approaches, ways of raising awareness about lynda.com on our campuses, lessons learned through implementation, reporting capabilities, and advice we would give for other campuses looking to offer this service

Continuous group cohomology with coefficients in locally analytic vectors of admissible Qp \mathbb{Q}_p -Banach space representations

We show that the continuous cohomology groups of a $p$-adic reductive group with coefficients in the locally analytic vectors of an admissible $\mathbb{Q}_p$-Banach space representation are homeomorphic to those with coefficients in the Banach space representation itself. Moreover, we deduce that the canonical topologies on those continuous cohomology groups are Hausdorff and are the uniquely determined finest locally convex topologies

Complement activation and its prognostic role in post-cardiac arrest patients

Cardiac arrest causes generalized ischemia/hypoxia, and subsequent resuscitation inflicts reperfusion injury, the pathology of which is not fully understood. Moreover, predicting the prognosis of comatose, post-cardiac-arrest patients is a complex clinical challenge. We hypothesized that the extent of complement activation might be a reliable predictor of mortality in this population. Forty-six comatose cardiac arrest patients were enrolled into our prospective cohort study, conducted in a tertiary care university clinic. All subjects were cooled to 32-34 degrees C body temperature for 24 hours and then, allowed to rewarm to normothermia. All patients underwent diagnostic coronary angiography. On admission, at 6 and at 24 hrs, blood samples were taken from the arterial catheter. In these, complement products (C3a, C3, C4d, C4, SC5b9, and Bb) were measured by ELISA in blood samples. Patients were followed-up for 30 days; 22 patients (47.8%) died by the end of this period. We observed that complement activation (determined as the C3a to C3 ratio) was higher in non-survivors than in survivors at each time point. In the multivariate Cox regression analysis, the C3a/C3 ratio determined 24 hours after the initiation of therapeutic hypothermia predicted 30-day mortality regardless of age, sex, and the APACHE II score. Complement activation occurs in post-cardiac arrest patients, and its extent correlates with 30-day survival. The C3a/C3 ratio might prove useful for estimating the prognosis of comatose post-cardiac-arrest patients. This article is protected by copyright. All rights reserved

Good for the Military - Bad for the Nation?

Has an overreliance on the military as a one-size-fits-all solution become so engrained that we no longer consider alternatives? Are domestic politics so intertwined with foreign affairs that the citizenry has no choice but to accept veterans to fill the ranks of the executive branch? Is there hope for the future? Can we rebalance the general orientation of our government? The outcome to all these questions can be arrived at in a favorable way if our military continues to embrace the Huntingtonian notion of objective control. If professionalism continues to guide the actions of our military’s senior leaders and those who serve in decision making bodies such as the National Security Council, there is hope for a reversal in what Lasswell describes as a “picture of the probable.

Civ-mil in Danger? Blame the pundits, not the academies.

I teach civil-military relations at the U.S. Military Academy at West Point. While searching for readings for an elective course taught in the spring semester, I came across a 2010 article written in the L.A. Times, “An increasingly politicized military.” One passage stood out: “By all accounts, the curricula of the service academies and the war colleges give remarkably little attention to the central importance of civilian control. They do not systematically expose up-and-coming officers to intensive case studies and simulations designed to give them a sense of the principle’s real-world implications.” So where are we now? Nearly a decade later, those cadets have graduated and are now midcareer officers. Do civilians have less control over the military as a result of the claim that the military received poor instruction on proper civ-mil relations? Can curriculum “fix” broken civilmilitary relations

Current Military Academy Service Obligation: Good for Civil-Military Relations

Imagine receiving a free undergraduate education at one of the best colleges in the United States. The military academies provide this. Any economist, however, will tell you that there is no such thing as a free lunch. The American tax payer foots the bill for all those who are admitted to attend one of the military’s academies. In exchange, these citizens will commission as officers and serve an obligation of five years on active duty. The most recent National Defense Authorization Act (NDAA) includes a section directing the Secretary of Defense to assess if this five-year service obligation should be extended. Congress is now questioning if the increase in the cost of educating and training should equate to an increase in time served for graduates. In short, is the nation getting “an adequate return on investment for a service academy graduate?

Play to Win: Sticking to a Playbook in the Competition with Russia

Russia docks a warship in Havana knowing it will provoke a response from the United States. How dare they. The US Navy dispatched a destroyer to shadow the vessel; after all, the United States has the Monroe doctrine to enforce. A few weeks prior, Russia sent around a hundred troops to Venezuela. This also provoked a response, albeit rhetorical. Despite these US reactions, Russia continues to play strategic games. Why did the United States respond to these actions in these ways? And what is the most appropriate response

The role of pain modulation in non-suicidal self-injury

Individuals with non-suicidal self-injury (NSSI) behavior tend to report feeling little or no pain when they self-injure. Moreover, in laboratory studies the NSSI population tends to demonstrate reduced sensitivity to painful stimuli. There is reason to believe that hypoalgesia could be a risk factor for developing and maintaining NSSI. Many theories have been proposed to explain the reduced sensitivity to pain in the NSSI population; some examples are dissociation, self-critical cognitive style, and low levels of endogenous opioids. However, the evidence supporting these theories are sparse. To understand why the NSSI population experiences less pain, there is a need for a better understanding of how individuals with NSSI process pain. We wanted to use methods that have been developed to study pain modulation in individuals with long-term pain to characterize the pain modulation system of women with ongoing NSSI. Our general hypothesis was that women with NSSI have a hyper-effective pain modulation system that inhibits pain to a greater extent and facilitates pain to a lesser extent, compared to women without NSSI. In Study I, a non-clinical population (N = 62) was recruited to test a pain testing protocol in order to produce offset analgesia (OA) and onset hyperalgesia (OH). Small deviations in a painful thermal stimulation have been found to produce disproportional hypoalgesic (OA) and hyperalgesic (OH) responses. Different stimulus ranges (±1°C and ±2°C) were included in the protocol to study the dynamic relation between heat and pain. The study was composed of two identical experiments. In experiment 1, we produced OA and OH responses, using ±2°C but not ±1°C. In experiment 2, we only produced OA responses, but no OH responses. Study II investigated if it was possible to induce sensory attenuation of pain in a non-clinical population (N = 40) by comparing self-administered pressure pain threshold to experimenteradministrated pressure pain threshold, using an algometer. An experimental condition, where the participants imagined that they pressed the algometer, was also included in the study, to examine if sensory attenuation could be induced with the help of imagery. Self-administered pressure was found to be less painful, compared to experimenter-administered pressure. Moreover, imagined self-administered pressure was also experienced as less painful than experimenter-administered pressure. Self-induced sensory attenuation of pain could be a factor in explaining hypoalgesia during NSSI. Study III consisted of an extensive battery of pain tests in order to study pain modulation in a sample of women with NSSI (N = 41) and an age-matched control group, consisting of healthy women (N = 40). The study also included a simple pain test combined with fMRI. We found that the NSSI group demonstrated higher pressure and heat pain thresholds, compared to the control group. The NSSI group also demonstrated a larger conditioned pain modulation (CPM) effect, compared to the control group. CPM is a test based on the principle pain inhibits pain, and is a measure of central down-regulation of pain. We found no difference between the groups regarding temporal summation of pain, a measure of pain facilitation, or in heat pain tolerance. Tonic painful heat stimulation produced a larger hemodynamic response in primary and secondary somatosensory cortex in the NSSI group, compared to the control group. In Study IV, we used the combined OA/OH protocol that was evaluated in Study I to study pain modulation in women with NSSI (N = 37) and controls (N = 39). The OA/OH protocol was combined with fMRI. Across groups, both the OA and the OH responses were significant. We also found a difference between the groups regarding the OH response, as the NSSI group demonstrated a weaker OH response, compared to the control group. The OH response was associated with a hemodynamic response in the primary somatosensory cortex, across groups, which suggests that the nociceptive signal was upregulated before reaching the brain. In line with our main hypothesis, we found that the NSSI group inhibited pain to a greater extent (CPM in Study III) and facilitated pain to a lesser extent (OH in Study IV), compared to the control group. These results suggest that women with NSSI have a hyper-effective pain modulation system. There were also results that did not support our main hypothesis; the NSSI group did not demonstrate weaker pain facilitation when tested with the temporal summation protocol (Study III) or stronger inhibition associated with OA (Study IV). An explanation could be that different pain tests measure different aspects of pain modulation and only certain pain modulation mechanisms are affected in the NSSI population. The studies of this thesis provide evidence that the previous findings of hypoalgesia in the NSSI population does not reflect response bias but is rooted in how the nervous system modulates nociceptive signals