Poetry and Narrative as Qualitative Data: Explorations into Existential Theory

This article explores existential principles through autoethnographic poetry and narrative reflections. The use of poetry and narrative as tools in qualitative research is explored. Poetry and narratives are shown to be valuable tools for presenting people’s lived experiences of complex existential principles and processes. The use of poetry and narrative in this research is positioned within the traditions of expressive arts and postmodern research methods. Indo-Pacific Journal of Phenomenology, Volume 7, Edition 1 May 200

Letter from Richard Furman to Reverend John Rippon (?)

Richard Furman writes to Reverend John Rippon regarding the aquisition of religious texts. Furman mentions his plans to attend a Presbyterian extraordinary meeting lasting 4 to 5 days. 13 May 1802 in the High Hills of the Santee.https://digitalcommons.wofford.edu/littlejohnmss/1150/thumbnail.jp

Variable access systems for architectural design

Thesis (M. Arch)--Massachusetts Institute of Technology, Dept. of Architecture, 1984.MICROFICHE COPY AVAILABLE IN ARCHIVES AND ROTCH.Includes bibliographical references.The purpose of this thesis is to develop an alternate process of architectural design based on a variety of schemes which respond to different aspects of any given project and site. The major focus of each exploration is the influence of pedestrian access on the building form. After the investigations are compiled a final projection will be synthesized as an assemblage of the strengths of each exploration. This method should enable the project to contain more than a strong design decision.by Richard Jonathon Furman.M.Arc

Lasing at a Stationary Inflection Point

The concept of lasers based on the frozen mode regime in active periodic optical waveguides with a 3rd-order exceptional point of degeneracy (EPD) is advanced. The frozen mode regime in a lossless and gainless waveguide is associated with a stationary inflection point (SIP) in the Bloch dispersion relation, where three Bloch eigenmodes coalesce forming the frozen mode. As a practical example, we consider an asymmetric serpentine optical waveguide (ASOW). An ASOW operating near the SIP frequency displays a large group delay of a non-resonant nature that scales as the cube of the waveguide length, leading to a strong gain enhancement when active material is included. Therefore, a laser operating in the close vicinity of an SIP has a gain threshold that scales as a negative cube of the waveguide length. We determine that this scaling law is maintained in the presence of small distributed losses, such as radiation associated with waveguide bends and roughness. In addition, we show that although gain causes a distortion in the modes coalescing at the SIP, the properties of the frozen mode are relatively resistant to such small perturbations and we still observe a large degree of exceptional degeneracy for gain values that bring the system above threshold. Finally, our study also reveals that lasing near an SIP is favored over lasing near a photonic band edge located in close proximity to the SIP. In particular, we observe that an SIP-induced lasing in an ASOW displays lower gain threshold compared to lasing near the photonic regular band edge (RBE), even though the SIP resonance has a lower quality factor than the RBE resonance

Combinations of idelalisib with rituximab and/or bendamustine in patients with recurrent indolent non-Hodgkin lymphoma

Key Points Combining phosphatidylinositol-3-kinase δ inhibition with rituximab, bendamustine, or both is feasible and active in relapsed iNHL. The safety of novel combinations should be proven in phase 3 trials before adoption in clinical practice.</jats:p

CD39 activity correlates with stage and inhibits platelet reactivity in chronic lymphocytic leukemia

<p>Abstract</p> <p>Background</p> <p>Chronic lymphocytic leukemia (CLL) is characterized by accumulation of mature appearing lymphocytes and is rarely complicated by thrombosis. One possible explanation for the paucity of thrombotic events in these patients may be the presence of the ecto-nucleotidase CD39/NTDPase-1 on the surface of the malignant cells in CLL. CD39 is the major promoter of platelet inhibition <it>in vivo </it>via its metabolism of ADP to AMP. We hypothesize that if CD39 is observed on CLL cells, then patients with CLL may be relatively protected against platelet aggregation and recruitment and that CD39 may have other effects on CLL, including modulation of the disease, via its metabolism of ATP.</p> <p>Methods</p> <p>Normal and malignant lymphocytes were isolated from whole blood from patients with CLL and healthy volunteers. Enzyme activity was measured via radio-TLC assay and expression via FACS. Semi-quantititative RT-PCR for CD39 splice variants and platelet function tests were performed on several samples.</p> <p>Results</p> <p>Functional assays demonstrated that ADPase and ATPase activities were much higher in CLL cells than in total lymphocytes from the normal population on a per cell basis (p-value < 0.00001). CD39 activity was elevated in stage 0–2 CLL compared to stage 3–4 (p < 0.01). FACS of lymphocytes demonstrated CD39 expression on > 90% of normal and malignant B-lymphocytes and ~8% of normal T-lymphocytes. RT-PCR showed increased full length CD39 and splice variant 1.5, but decreased variant 1.3 in CLL cells. Platelet function tests showed inhibition of platelet activation and recruitment to ADP by CLL cells.</p> <p>Conclusion</p> <p>CD39 is expressed and active on CLL cells. Enzyme activity is higher in earlier stages of CLL and decreased enzyme activity may be associated with worsening disease. These results suggest that CD39 may play a role in the pathogenesis of malignancy and protect CLL patients from thrombotic events.</p

Hamiltonian domain wall fermions at strong coupling

We apply strong-coupling perturbation theory to gauge theories containing domain-wall fermions in Shamir's surface version. We construct the effective Hamiltonian for the color-singlet degrees of freedom that constitute the low-lying spectrum at strong coupling. We show that the effective theory is identical to that derived from naive, doubled fermions with a mass term, and hence that domain-wall fermions at strong coupling suffer both doubling and explicit breaking of chiral symmetry. Since we employ a continuous fifth dimension whose extent tends to infinity, our result applies to overlap fermions as well.Comment: Revtex, 21 pp. Some changes in Introduction, dealing with consistency with previous wor