5,329 research outputs found
K-orbit closures on G/B as universal degeneracy loci for flagged vector bundles with symmetric or skew-symmetric bilinear form
We use equivariant localization and divided difference operators to determine
formulas for the torus-equivariant fundamental cohomology classes of -orbit
closures on the flag variety , where G = GL(n,\C), and where is one
of the symmetric subgroups O(n,\C) or Sp(n,\C). We realize these orbit
closures as universal degeneracy loci for a vector bundle over a variety
equipped with a single flag of subbundles and a nondegenerate symmetric or
skew-symmetric bilinear form taking values in the trivial bundle. We describe
how our equivariant formulas can be interpreted as giving formulas for the
classes of such loci in terms of the Chern classes of the various bundles.Comment: Minor revisions and corrections suggested by referees. Final version,
to appear in Transformation Group
Calibration of <i>Herschel</i> SPIRE FTS observations at different spectral resolutions
The SPIRE Fourier Transform Spectrometer on-board the Herschel Space Observatory had two standard spectral resolution modes for science observations: high resolution (HR) and low resolution (LR), which could also be performed in sequence (H+LR). A comparison of the HR and LR resolution spectra taken in this sequential mode revealed a systematic discrepancy in the continuum level. Analysing the data at different stages during standard pipeline processing demonstrates that the telescope and instrument emission affect HR and H+LR observations in a systematically different way. The origin of this difference is found to lie in the variation of both the telescope and instrument response functions, while it is triggered by fast variation of the instrument temperatures. As it is not possible to trace the evolution of the response functions using housekeeping data from the instrument subsystems, the calibration cannot be corrected analytically. Therefore, an empirical correction for LR spectra has been developed, which removes the systematic noise introduced by the variation of the response functions
Schur Q-functions and degeneracy locus formulas for morphisms with symmetries
We give closed-form formulas for the fundamental classes of degeneracy loci
associated with vector bundle maps given locally by (not necessary square)
matrices which are symmetric (resp. skew-symmetric) w.r.t. the main diagonal.
Our description uses essentially Schur Q-polynomials of a bundle, and is based
on a certain push-forward formula for these polynomials in a Grassmann bundle.Comment: 22 pages, AMSTEX, misprints corrected, exposition improved. to appear
in the Proceedings of Intersection Theory Conference in Bologna, "Progress in
Mathematics", Birkhause
Box ball system associated with antisymmetric tensor crystals
A new box ball system associated with an antisymmetric tensor crystal of the
quantum affine algebra of type A is considered. This includes the so-called
colored box ball system with capacity 1 as the simplest case. Infinite number
of conserved quantities are constructed and the scattering rule of two olitons
are given explicitly.Comment: 15 page
Radiation from a Charge Uniformly Accelerated for All Time
A recent paper of Singal [Gen. Rel. Grav. 27 (1995), 953-967] argues that a
uniformly accelerated particle does not radiate, in contradiction to the
consensus of the research literature over the past 30 years. This note points
out some questionable aspects of Singal's argument and shows how similar
calculations can lead to the opposite conclusion.Comment: LaTeX, 9 pages, to appear in General Relativity and Gravitatio
Entanglement and Symmetry: A Case Study in Superselection Rules, Reference Frames, and Beyond
This paper concentrates on a particular example of a constraint imposed by
superselection rules (SSRs): that which applies when the parties (Alice and
Bob) cannot distinguish among certain quantum objects they have. This arises
naturally in the context of ensemble quantum information processing such as in
liquid NMR. We discuss how a SSR for the symmetric group can be applied, and
show how the extractable entanglement can be calculated analytically in certain
cases, with a maximum bipartite entanglement in an ensemble of N Bell-state
pairs scaling as log(N) as N goes to infinity . We discuss the apparent
disparity with the asymptotic (N >> 1) recovery of unconstrained entanglement
for other sorts of superselection rules, and show that the disparity disappears
when the correct notion of applying the symmetric group SSR to multiple copies
is used. Next we discuss reference frames in the context of this SSR, showing
the relation to the work of von Korff and Kempe [Phys. Rev. Lett. 93, 260502
(2004)]. The action of a reference frame can be regarded as the analog of
activation in mixed-state entanglement. We also discuss the analog of
distillation: there exist states such that one copy can act as an imperfect
reference frame for another copy. Finally we present an example of a stronger
operational constraint, that operations must be non-collective as well as
symmetric. Even under this stronger constraint we nevertheless show that
Bell-nonlocality (and hence entanglement) can be demonstrated for an ensemble
of N Bell-state pairs no matter how large N is. This last work is a
generalization of that of Mermin [Phys. Rev. D 22, 356 (1980)].Comment: 16 pages, 6 figures. v2 updated version published in Phys Rev
Lie group weight multiplicities from conformal field theory
Dominant weight multiplicities of simple Lie groups are expressed in terms of
the modular matrices of Wess-Zumino-Witten conformal field theories, and
related objects. Symmetries of the modular matrices give rise to new relations
among multiplicities. At least for some Lie groups, these new relations are
strong enough to completely fix all multiplicities.Comment: 12 pages, Plain TeX, no figure
Hyperinsulinism-hyperammonaemia syndrome: novel mutations in the GLUD1 gene and genotype-phenotype correlations
Background: Activating mutations in the GLUD1 gene (which encodes for the intra-mitochondrial enzyme glutamate dehydrogenase, GDH) cause the hyperinsulinism–hyperammonaemia (HI/HA) syndrome. Patients present with HA and leucine-sensitive hypoglycaemia. GDH is regulated by another intra-mitochondrial enzyme sirtuin 4 (SIRT4). Sirt4 knockout mice demonstrate activation of GDH with increased amino acid-stimulated insulin secretion.
Objectives: To study the genotype–phenotype correlations in patients with GLUD1 mutations. To report the phenotype and functional analysis of a novel mutation (P436L) in the GLUD1 gene associated with the absence of HA.
Patients and methods: Twenty patients with HI from 16 families had mutational analysis of the GLUD1 gene in view of HA (n=19) or leucine sensitivity (n=1). Patients negative for a GLUD1 mutation had sequence analysis of the SIRT4 gene. Functional analysis of the novel P436L GLUD1 mutation was performed.
Results: Heterozygous missense mutations were detected in 15 patients with HI/HA, 2 of which are novel (N410D and D451V). In addition, a patient with a normal serum ammonia concentration (21 µmol/l) was heterozygous for a novel missense mutation P436L. Functional analysis of this mutation confirms that it is associated with a loss of GTP inhibition. Seizure disorder was common (43%) in our cohort of patients with a GLUD1 mutation. No mutations in the SIRT4 gene were identified.
Conclusion: Patients with HI due to mutations in the GLUD1 gene may have normal serum ammonia concentrations. Hence, GLUD1 mutational analysis may be indicated in patients with leucine sensitivity; even in the absence of HA. A high frequency of epilepsy (43%) was observed in our patients with GLUD1 mutations
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