ダイ4ジ ナンキョク チイキ カンソクタイ ウチュウセン ブモン センジョウ カンソク ホウコク

The third latitude survey in cosmic-ray neutrons has been carried out along the same ship-route and by using the same apparatus as in the preceeding two surveys. Although the observation room was the same as that in the second survey, one additional room was constructed over our room. Thus, as observational conditions in the three latitude surveys are different from one another, the obtained results could not be compared in absolute intensity but in relative. The periods during which each survey was performed are represented with the corresponding sunspot relative numbers in Fig. 1, where a full curve shows the 12 months running average of monthly mean values in sunspot numbers. Fig. 2 shows 12 hour mean values for each latitude curve in the southern hemisphere. It is seen from the figure that the slope of latitude curve becomes gentle at the second survey and then almost recovers at the third. To explain such changes in primary cosmic-rays by terms of changes in solar activity represented by sunspot numbers as shown in Fig. 1, we suppose a hysteresis effect of solar activity upon cosmic-rays. In other words, changes in cosmic-rays do not immediately follow that in solar activity but about half a year later

Functional network of glycan-related molecules: Glyco-Net in Glycoconjugate Data Bank

<p>Abstract</p> <p>Background</p> <p>Glycans are involved in a wide range of biological process, and they play an essential role in functions such as cell differentiation, cell adhesion, pathogen-host recognition, toxin-receptor interactions, signal transduction, cancer metastasis, and immune responses. Elucidating pathways related to post-translational modifications (PTMs) such as glycosylation are of growing importance in post-genome science and technology. Graphical networks describing the relationships among glycan-related molecules, including genes, proteins, lipids and various biological events are considered extremely valuable and convenient tools for the systematic investigation of PTMs. However, there is no database which dynamically draws functional networks related to glycans.</p> <p>Description</p> <p>We have created a database called Glyco-Net <url>http://www.glycoconjugate.jp/functions/</url>, with many binary relationships among glycan-related molecules. Using search results, we can dynamically draw figures of the functional relationships among these components with nodes and arrows. A certain molecule or event corresponds to a node in the network figures, and the relationship between the molecule and the event are indicated by arrows. Since all components are treated equally, an arrow is also a node.</p> <p>Conclusions</p> <p>In this paper, we describe our new database, Glyco-Net, which is the first database to dynamically show networks of the functional profiles of glycan related molecules. The graphical networks will assist in the understanding of the role of the PTMs. In addition, since various kinds of bio-objects such as genes, proteins, and inhibitors are equally treated in Glyco-Net, we can obtain a large amount of information on the PTMs.</p

Deep Neural Networks - A Brief History

Introduction to deep neural networks and their history.Comment: 14 pages, 14 figure

Observational signatures of forming young massive clusters: continuum emission from dense HII regions

Young massive clusters (YMCs) are the most massive star clusters forming in nearby galaxies and are thought to be a young analogue to the globular clusters. Understanding the formation process of YMCs leads to looking into very efficient star formation in high-redshift galaxies suggested by recent JWST observations. We investigate possible observational signatures of their formation stage, particularly when the mass of a cluster is increasing via accretion from a natal molecular cloud. To this end, we study the broad-band continuum emission from ionized gas and dust enshrouding YMCs, whose formation is followed by recent radiation-hydrodynamics simulations. We perform post-process radiative transfer calculations using simulation snapshots and find characteristic spectral features at radio and far-infrared frequencies. We show that a striking feature is long-lasting, strong free-free emission from a $\sim$ 10pc-scale HII region with a large emission measure of $\gtrsim 10^7 \mathrm{cm}^{-6} \ \mathrm{pc}$, corresponding to the mean electron density of $\gtrsim 10^3~\mathrm{cm}^{-3}$. There is a turnover feature below $\sim$ 10 GHz, a signature of the optically-thick free-free emission, often found in Galactic ultra-compact HII regions. These features come from the peculiar YMC formation process, where the cluster's gravity effectively traps photoionized gas for a long duration and enables continuous star formation within the cluster. Such large and dense HII regions show distinct distribution on the density-size diagram, apart from the standard sequence of Galactic HII regions. This is consistent with the observational trend inferred for extragalactic HII regions associated with YMCs.Comment: 12 pages, 10 figures, accepted for publication in MNRA

Language development in Japanese children who receive cochlear implant and/or hearing aid

Objectives: This study aimed to investigate a wide variety of factors that influence auditory, speech, and language development following pediatric cochlear implantation (CI). Study design: Prospective collection of language tested data in profound hearing-impaired children. Hypothesis: Pediatric CI can potentially be effective to development of practical communication skills and early implantation is more effective. Methods: We proposed a set of language tests (assessment package of the language development for Japanese hearing-impaired children; ALADJIN) consisting of communication skills testing (test for question-answer interaction development; TQAID), comprehensive (Peabody Picture Vocabulary Test-Revised; PVT-R and Standardized Comprehension Test for Abstract Words; SCTAW) and productive vocabulary (Word Fluency Test; WFT), and comprehensive and productive syntax (Syntactic processing Test for Aphasia; STA). Of 638 hearing-impaired children recruited for this study, 282 (44.2%) with >70 dB hearing impairment had undergone CI. After excluding children with low birth weight (11 points on the Pervasive Developmental Disorder ASJ Rating Scale for the test of autistic tendency, and those <2 SD on Raven's Colored Progressive Matrices for the test of non-verbal intelligence, 190 children were subjected to this set of language tests. Results: Sixty children (31.6%) were unilateral CI-only users, 128 (67.4%) were CI-hearing aid (HA) users, and 2 (1.1%) were bilateral CI users. Hearing loss level of CI users was significantly (p < 0.01) worse than that of HA-only users. However, the threshold level, maximum speech discrimination score, and speech intelligibility rating in CI users were significantly (p < 0.01) better than those in HA-only users. The scores for PVT-R (p < 0.01), SCTAW, and WET in CI users were better than those in HA-only users. STA and TQAID scores in CI-HA users were significantly (p < 0.05) better than those in unilateral CI-only users. The high correlation (r = 0.52) has been found between the age of CI and maximum speech discrimination score. The scores of speech and language tests in the implanted children before 24 months of age have been better than those in the implanted children after 24 months of age. Conclusions: We could indicate that CI was effective for language development in Japanese hearing-impaired children and early CI was more effective for productive vocabulary and syntax.ArticleINTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY. 76(3):433-438 (2012)journal articl

Cochlear Implantation in the Poorer-Hearing Ear Is a Reasonable Choice

Choosing the optimal side for cochlear implantation (CI) remains a major challenge because of the lack of evidence. We investigated the choice of the surgery side for CI (i.e., the better- or poorer-hearing ear) in patients with asymmetric hearing. Audiological records of 74 adults with a unilateral hearing aid who had undergone surgery at Okayama University Hospital were reviewed. The definition of ‘better-hearing ear’ was the aided ear, and the unaided ear was considered the poorer-hearing ear. We performed a multiple regression analysis to identify potential predictors of speech recognition performance after unilateral CI in the patients. Fifty-two patients underwent CI in the poorer-hearing ear. The post-Ci bimodal hearing rate was far higher in the poorer-ear group (77.8% vs. 22.2%). A multivariate analysis revealed that prelingual hearing loss and the patient’s age at CI significantly affected the speech recognition outcome (beta coefficients: 24.6 and −0.33, 95% confidence intervals [11.75-37.45] and [−0.58 to −0.09], respectively), but the CI surgery side did not (−6.76, [−14.92-1.39]). Unilateral CI in the poorer-hearing ear may therefore be a reasonable choice for adult patients with postlingual severe hearing loss, providing a greater opportunity for postoperative bimodal hearing