PREFRONTAL ACTIVATION DURING EMOTIONAL EXPERIENCE AS MEASURED BY NIRS

To investigate brain activation in the prefrontal cortex (PFC) during emotional experiences, we examined blood oxygenation changes of healthy female volunteers by using multi-channel Near Infrared Spectroscopy (NIRS). Results directly confirmed that the PFC was activated during emotional tasks suggesting that the levels of oxy-Hb increased significantly larger in negative periods compared with positive or neutral in the bilateral dorsolateral PFC. There is a possibility that this brain area is associated with the regulation of negative emotion. Our results suggest that it may be possible to evaluate emotional changes using NIRS sensitively

Outcomes in Newly Diagnosed Atrial Fibrillation and History of Acute Coronary Syndromes: Insights from GARFIELD-AF

BACKGROUND: Many patients with atrial fibrillation have concomitant coronary artery disease with or without acute coronary syndromes and are in need of additional antithrombotic therapy. There are few data on the long-term clinical outcome of atrial fibrillation patients with a history of acute coronary syndrome. This is a 2-year study of atrial fibrillation patients with or without a history of acute coronary syndromes