356 research outputs found
An inertial range length scale in structure functions
It is shown using experimental and numerical data that within the traditional
inertial subrange defined by where the third order structure function is linear
that the higher order structure function scaling exponents for longitudinal and
transverse structure functions converge only over larger scales, , where
has scaling intermediate between and as a function of
. Below these scales, scaling exponents cannot be determined for any
of the structure functions without resorting to procedures such as extended
self-similarity (ESS). With ESS, different longitudinal and transverse higher
order exponents are obtained that are consistent with earlier results. The
relationship of these statistics to derivative and pressure statistics, to
turbulent structures and to length scales is discussed.Comment: 25 pages, 9 figure
Development of a novel integrated iontophoresis electrode consisting of metallic and drug-loaded layers
Strong Universality in Forced and Decaying Turbulence
The weak version of universality in turbulence refers to the independence of
the scaling exponents of the th order strcuture functions from the
statistics of the forcing. The strong version includes universality of the
coefficients of the structure functions in the isotropic sector, once
normalized by the mean energy flux. We demonstrate that shell models of
turbulence exhibit strong universality for both forced and decaying turbulence.
The exponents {\em and} the normalized coefficients are time independent in
decaying turbulence, forcing independent in forced turbulence, and equal for
decaying and forced turbulence. We conjecture that this is also the case for
Navier-Stokes turbulence.Comment: RevTex 4, 10 pages, 5 Figures (included), 1 Table; PRE, submitte
Anomalous scaling, nonlocality and anisotropy in a model of the passively advected vector field
A model of the passive vector quantity advected by a Gaussian
time-decorrelated self-similar velocity field is studied; the effects of
pressure and large-scale anisotropy are discussed. The inertial-range behavior
of the pair correlation function is described by an infinite family of scaling
exponents, which satisfy exact transcendental equations derived explicitly in d
dimensions. The exponents are organized in a hierarchical order according to
their degree of anisotropy, with the spectrum unbounded from above and the
leading exponent coming from the isotropic sector. For the higher-order
structure functions, the anomalous scaling behavior is a consequence of the
existence in the corresponding operator product expansions of ``dangerous''
composite operators, whose negative critical dimensions determine the
exponents. A close formal resemblance of the model with the stirred NS equation
reveals itself in the mixing of operators. Using the RG, the anomalous
exponents are calculated in the one-loop approximation for the even structure
functions up to the twelfth order.Comment: 37 pages, 4 figures, REVTe
Ectopic thymoma presenting as a giant intrathoracic tumor: A case report
Ectopic thymoma rarely presents as an intrathoracic tumor. We report a case of ectopic thymoma presenting as a giant right intrathoracic tumor that was treated with resection. The patient was a 50-year-old Japanese woman who presented with the chief complaint of chest pain. Detailed examination revealed a solid tumor measuring 15 × 10 × 8 cm in diameter, with a clear border. The Imaging findings suggested a solitary fibrous tumor, and surgery was performed. At surgery, the tumor was found to beadherent to the diaphragm, mediastinal pleura, and lower lobe of the lung, although it could be dissected with relative ease and was removed. Pathological diagnosis indicated a type B1 tumor with no capsular invasion according to the World Health Organization classification, and a diagnosis of Masaoka stage I thymoma was made. No continuity with the normal thymus tissue was seen, and the thymoma was considered to be derived from ectopic thymic tissue in the pleura
Amylase α-2A Autoantibodies: Novel Marker of Autoimmune Pancreatitis and Fulminant Type 1 Diabetes
OBJECTIVE— The pathogenesis of autoimmune pancreatitis (AIP) and fulminant type 1 diabetes remains unclear, although it is known that immune-mediated processes severely compromise the endocrine and exocrine functions in both diseases
Gallbladder adenocarcinoma with human chorionic gonadotropin: a case report and review of literature
<p>Abstract</p> <p>Background</p> <p>The case of adenocarcinoma with human chorionic gonadtropin (HCG), primary in the male gallbladder, is extremely rare. A Medline search has shown only a few similar cases reported.</p> <p>Methods</p> <p>We herein describe a case of primary gallbladder adenocarcinoma associated by ectopic HCG positive tumor cells in a 79-year-old male.</p> <p>Results</p> <p>Pathological examination showed a mixture of moderately and poorly differentiated adenocarcinoma with ectopic HCG and placental alkaline phosphatase (PlAP) in tumor cells, though the increase of serum or urinary HCG secretion was not confirmed. The literatures were also reviewed.</p> <p>Conclusions</p> <p>A case of gallbladder cancer with ectopic HCG production is quite rare in the literature, though many similar cases in other site, especially in GI tract, are reported. Embryological consideration suggests the increased frequency of similar cases more than being thought now.</p
Sequence analysis of the Epstein-Barr virus (EBV) BRLF1 gene in nasopharyngeal and gastric carcinomas
<p>Abstract</p> <p>Background</p> <p>Epstein-Barr virus (EBV) has a biphasic infection cycle consisting of a latent and a lytic replicative phase. The product of immediate-early gene BRLF1, Rta, is able to disrupt the latency phase in epithelial cells and certain B-cell lines. The protein Rta is a frequent target of the EBV-induced cytotoxic T cell response. In spite of our good understanding of this protein, little is known for the gene polymorphism of BRLF1.</p> <p>Results</p> <p>BRLF1 gene was successfully amplified in 34 EBV-associated gastric carcinomas (EBVaGCs), 57 nasopharyngeal carcinomas (NPCs) and 28 throat washings (TWs) samples from healthy donors followed by PCR-direct sequencing. Fourteen loci were found to be affected by amino acid changes, 17 loci by silent nucleotide changes. According to the phylogenetic tree, 5 distinct subtypes of BRLF1 were identified, and 2 subtypes BR1-A and BR1-C were detected in 42.9% (51/119), 42.0% (50/119) of samples, respectively. The distribution of these 2 subtypes among 3 types of specimens was significantly different. The subtype BR1-A preferentially existed in healthy donors, while BR1-C was seen more in biopsies of NPC. A silent mutation A/G was detected in all the isolates. Among 3 functional domains, the dimerization domain of Rta showed a stably conserved sequence, while DNA binding and transactivation domains were detected to have multiple mutations. Three of 16 CTL epitopes, NAA, QKE and ERP, were affected by amino acid changes. Epitope ERP was relatively conserved; epitopes NAA and QKE harbored more mutations.</p> <p>Conclusions</p> <p>This first detailed investigation of sequence variations in BRLF1 gene has identified 5 distinct subtypes. Two subtypes BR1-A and BR1-C are the dominant genotypes of BRLF1. The subtype BR1-C is more frequent in NPCs, while BR1-A preferentially presents in healthy donors. BR1-C may be associated with the tumorigenesis of NPC.</p
Digestible Lysine on Live Performance of Chicken Type Naked Neck During the Starter Phase
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