164 research outputs found
Analysis of the (N,xN') reactions by quantum molecular dynamics plus statistical decay model
We propose a model based on quantum molecular dynamics (QMD) incorporated with statistical decay model (SDM) to describe various nuclear reactions in an unified way. In this first part of the work, the basic ingredients of the model are defined and the model is applied systematically to the nucleon(N)-induced reactions. It has been found that our model can give a remarkable agreement in the energy-angle double differential cross sections of (N,xN') type reactions for incident energies from 100 MeV to 3 GeV with a fixed parameter set. An unified description of the major three reaction mechanisms of (N,xN') reactions, i.e. compound, pre-equilibrium and spallation processes, is given with our model
Analysis of proton-induced fragment production cross sections by the Quantum Molecular Dynamics plus Statistical Decay Model
The production cross sections of various fragments from proton-induced
reactions on Fe and Al have been analyzed by the Quantum
Molecular Dynamics (QMD) plus Statistical Decay Model (SDM). It was found that
the mass and charge distributions calculated with and without the statistical
decay have very different shapes. These results also depend strongly on the
impact parameter, showing an importance of the dynamical treatment as realized
by the QMD approach. The calculated results were compared with experimental
data in the energy region from 50 MeV to 5 GeV. The QMD+SDM calculation could
reproduce the production cross sections of the light clusters and
intermediate-mass to heavy fragments in a good accuracy. The production cross
section of Be was, however, underpredicted by approximately 2 orders of
magnitude, showing the necessity of another reaction mechanism not taken into
account in the present model.Comment: 12 pages, Latex is used, 6 Postscript figures are available by
request from [email protected]
Towards a More Complete and Accurate Experimental Nuclear Reaction Data Library (EXFOR): International Collaboration Between Nuclear Reaction Data Centres (NRDC)
The International Network of Nuclear Reaction Data Centres (NRDC) coordinated
by the IAEA Nuclear Data Section (NDS) is successfully collaborating in the
maintenance and development of the EXFOR library. As the scope of published
data expands (e.g., to higher energy, to heavier projectile) to meet the needs
from the frontier of sciences and applications, it becomes nowadays a hard and
challenging task to maintain both completeness and accuracy of the whole EXFOR
library. The paper describes evolution of the library with highlights on recent
developments.Comment: 4 pages, 2 figure
Effect of Respiratory Syncytial Virus Infection on Plasmacytoid Dendritic Cell Regulation of Allergic Airway Inflammation.
Background: Respiratory syncytial virus (RSV) can infect myeloid dendritic cells (mDCs) and regulate their function in the development of allergy. It has been widely reported that plasmacytoid DCs (pDCs) play a critical role in antiviral innate immunity. In contrast, not much is known about the role of pDCs in the interaction between allergy and viral infection. The purpose of the present study was to investigate the effect of RSV infection on pDC function in the regulation of allergic airway inflammation in a murine model of Dermatophagoides farinae-sensitized allergic asthma. Methods: Splenic pDCs isolated from D. farinae-sensitized donor mice were infected with live RSV ex vivo. Subsequently, these pDCs were inoculated into the airways of D. farinae-sensitized recipient mice. Lung pathology, lung tissue cytokine profiles, the number of regulatory T cells (T(reg)) and mDCs as well as the effects of IL-10 neutralization in the lung tissue of recipient mice were determined. Results: Intranasal inoculation of D. farinae-sensitized pDCs significantly inhibited the development of allergic airway inflammation and both Th1 and Th2 immunity. Live RSV infection of these pDCs prior to inoculation interfered with their inhibitory effects through decreasing T(reg) and IL-10 and increasing mDCs. Conclusions: In asthmatic airways, pDCs mediate tolerance to inhaled allergens through the regulation of T(reg), IL-10 and mDCs. RSV infection of pDCs potentially inhibits their immunotolerogenic effects and thus exacerbates allergic airway inflammation
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