63 research outputs found
Origin of the anomalous mass renormalization in metallic quantum well states of correlated oxide SrVO
angle-resolved photoemission spectroscopy (ARPES) has been
performed on SrVO ultrathin films, which show metallic quantum well (QW)
states, to unveil the origin of the anomalous mass enhancement in the QW
subbands. The line-shape analysis of the ARPES spectra reveals that the
strength of the electron correlation increases as the subband bottom energy
approaches the Fermi level. These results indicate that the anomalous
subband-dependent mass enhancement mainly arises from the quasi-one-dimensional
character of confined V states as a result of their orbital-selective
quantization.Comment: 6 pages, 3 figure
Emergence of quantum critical behavior in metallic quantum-well states of strongly correlated oxides
Controlling quantum critical phenomena in strongly correlated electron
systems, which emerge in the neighborhood of a quantum phase transition, is a
major challenge in modern condensed matter physics. Quantum critical phenomena
are generated from the delicate balance between long-range order and its
quantum fluctuation. So far, the nature of quantum phase transitions has been
investigated by changing a limited number of external parameters such as
pressure and magnetic field. We propose a new approach for investigating
quantum criticality by changing the strength of quantum fluctuation that is
controlled by the dimensional crossover in metallic quantum well (QW)
structures of strongly correlated oxides. With reducing layer thickness to the
critical thickness of metal-insulator transition, crossover from a Fermi liquid
to a non-Fermi liquid has clearly been observed in the metallic QW of SrVO
by \textit{in situ} angle-resolved photoemission spectroscopy. Non-Fermi liquid
behavior with the critical exponent is found to emerge in the
two-dimensional limit of the metallic QW states, indicating that a quantum
critical point exists in the neighborhood of the thickness-dependent Mott
transition. These results suggest that artificial QW structures provide a
unique platform for investigating novel quantum phenomena in strongly
correlated oxides in a controllable fashion.Comment: 6 pages, 3 figure
Detection of Salivary miRNAs That Predict Chronic Periodontitis Progression: A Cohort Study
The aim of this two-year cohort study was to investigate salivary microRNAs (miRNAs) that predict periodontitis progression. A total of 120 patients who underwent supportive periodontal therapy were recruited. Unstimulated whole saliva was collected at baseline. Two years later, 44 patients were followed up (median age, 67.1 years) and divided into two groups: progression group (n = 22), with one or more sites with clinical attachment level (CAL) progression (>3 mm compared with baseline) or tooth extraction due to periodontitis progression; and the control group (n = 22), which did not exhibit CAL progression. In the microarray analysis of salivary miRNAs, hsa-miR-5571-5p, hsa-miR-17-3p, hsa-let-7f-5p, hsa-miR-4724-3p, hsa-miR-99a-5p, hsa-miR-200a-3p, hsa-miR-28-5p, hsa-miR-320d, and hsa-miR-31-5p showed fold change values = 2.0 in the progression group compared with the control group (p 0.7, indicating fair discrimination power. The expressions of salivary hsa-miR-5571-5p, hsa-let-7f-5p, hsa-miR-99a-5p, hsa-miR-28-5p, and hsa-miR-320d were associated with periodontitis progression in patients with chronic periodontitis. These salivary miRNAs may be new biomarkers for progression of periodontitis, and monitoring them may contribute to new diagnostics and precision medicine for periodontitis
Relationship of Salivary Microbiome with the Worsening of the Periodontal Health Status in Young Adults: A 3-Year Cohort Study
The purpose of this prospective cohort study was to investigate the influence of the salivary microbiome on the worsening of the periodontal health status among Japanese young adults. We assessed the data of systemically healthy and non-smoking young (18-22 years) university students (n = 457) from Okayama University at baseline (2013) and follow-up (2016). The worsening group was defined based on an increase in the percentage of bleeding on probing (%BOP) or an increase in probing pocket depth (PPD) from = 4 mm. Unstimulated saliva samples were randomly collected from 69 students for microbiome analysis at follow-up. The salivary microbiome was assessed through 16S rRNA metagenomic sequencing. The type of community in the salivary microbiome clustered by statistical analysis and diversity was not significantly associated with the worsening of the periodontal health status in cases of increasing %BOP and PPD (p > 0.05). The prevalence of some species was significantly higher in the worsening group than in the non-worsening group (p < 0.05) in both cases. The worsening of the periodontal health status was associated with some species, but not the type of community and diversity in the salivary microbiome among Japanese young adults
Caries Increment and Salivary Microbiome during University Life: A Prospective Cohort Study
The purpose of this 3-year prospective cohort study was to explore the relationship between an increase in dental caries and oral microbiome among Japanese university students. We analyzed 487 students who volunteered to receive oral examinations and answer baseline (2013) and follow-up (2016) questionnaires. Of these students, salivary samples were randomly collected from 55 students at follow-up and analyzed using next-generation sequencing. Students were divided into two groups: increased group (Delta decayed, missing, and filled teeth (Delta DMFT) score increased during the 3-year period) and non-increased group (Delta DMFT did not increase). Thirteen phyla, 21 classes, 32 orders, 48 families, 72 genera, and 156 species were identified. Microbial diversity in the increased group (n = 14) was similar to that in the non-increased group (n = 41). Relative abundances of the family Prevotellaceae (p = 0.007) and genera Alloprevotella (p = 0.007) and Dialister (p = 0.039) were enriched in the increased group compared with the non-increased group. Some bacterial taxonomic clades were differentially present between the two groups. These results may contribute to the development of new dental caries prevention strategies, including the development of detection kits and enlightenment activities for these bacteria
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