The Effects of Humour in Online Recruitment Advertising

This study explores humour in recruitment advertising by examining the effects on job seekers of humour in online job advertisements. The results from an experimental study in which the humour content in job ads was manipulated indicate that humour negatively affected job seekers' attitudes towards the job ad, the company, and the job. However, humour content had no effect on job seekers' attitudes towards the managers depicted in the ads and no impact on intentions to apply for the job. Yet humour content enhanced intentions to share job ads, which is an important marketing response given the increased importance of social media. The study contributes to the growing literature on humour in advertising and to the literature on recruitment advertising by investigating the use of humour in the hitherto unexplored job advertising context

Estimated GFR and the Effect of Intensive Blood Pressure Lowering After Acute Intracerebral Hemorrhage

BackgroundThe kidney-brain interaction has been a topic of growing interest. Past studies of the effect of kidney function on intracerebral hemorrhage (ICH) outcomes have yielded inconsistent findings. Although the second, main phase of the Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial (INTERACT2) suggests the effectiveness of early intensive blood pressure (BP) lowering in improving functional recovery after ICH, the balance of potential benefits and harms of this treatment in those with decreased kidney function remains uncertain.Study DesignSecondary analysis of INTERACT2, which randomly assigned patients with ICH with elevated systolic BP (SBP) to intensive (target SBP<140mmHg) or contemporaneous guideline-based (target SBP<180mmHg) BP management.Setting & Participants2,823 patients from 144 clinical hospitals in 21 countries.PredictorsAdmission estimated glomerular filtration rates (eGFRs) of patients were categorized into 3 groups based on the CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration) creatinine equation: normal or high, mildly decreased, and moderately to severely decreased (>90, 60-90, and <60mL/min/1.73m2, respectively).OutcomesThe effect of admission eGFR on the primary outcome of death or major disability at 90 days (defined as modified Rankin Scale scores of 3-6) was analyzed using a multivariable logistic regression model. Potential effect modification of intensive BP lowering treatment by admission eGFR was assessed by interaction terms.ResultsOf 2,623 included participants, 912 (35%) and 280 (11%) had mildly and moderately/severely decreased eGFRs, respectively. Patients with moderately/severely decreased eGFRs had the greatest risk for death or major disability at 90 days (adjusted OR, 1.82; 95% CI, 1.28-2.61). Effects of early intensive BP lowering were consistent across different eGFRs (P=0.5 for homogeneity).LimitationsGeneralizability issues arising from a clinical trial population.ConclusionsDecreased eGFR predicts poor outcome in acute ICH. Early intensive BP lowering provides similar treatment effects in patients with ICH with decreased eGFRs