Disentangling the Relationship between Portfolio Homogenization and Transaction of Non-fungible Tokens

There has been an explosion in the popularity of Non-Fungible Tokens (NFTs), drawing attention from practitioners and scholars alike since 2021. Each NFT denotes a digital asset in the likes of an artwork, a tweet, or a video that is recorded on the blockchain with a unique identifying code. In turn, the emergence of NFTs has transformed the digital asset landscape. With the rapid growth of the NFT market, there is a concern that the market is becoming increasingly homogenized due to readily available blockchain technologies and relatively low costs of NFT mints. To this end, this study attempts to elucidate how NFT portfolio homogenization affects transaction volume and variation in the marketplace. Particularly, we collected and analyzed a dataset of 2,004 collections comprising 7,151,515 NFTs from OpenSea, a leading NFT platform. We discovered significant inverted U-shaped relationships between NFT portfolio homogenization and transaction variation and transaction volume

Research on Dual-Variable Integrated Electro-Hydrostatic Actuator

AbstractThe integrated electro-hydrostatic actuator (EHA) with variable displacement and variable rotation speed is researched. In the system, the output of the actuator is changed by controlling the rotation speed of the brushless DC servomotor and the displacement of the servopump. The mathematical model described in state space model is created. The system characteristics are studied based on the point of multiplicative dual variable. And the basic method of control of the system is presented

One Small Step for an Inflaton, One Giant Leap for Inflation: a novel non-Gaussian tail and primordial black holes

We report a novel prediction from single-field inflation that even a tiny step in the inflaton potential can change our perception of primordial non-Gaussianities of the curvature perturbation. Our analysis focuses on the tail of probability distribution generated by an upward step transition between two stages of slow-roll evolution. The nontrivial background dynamics with off-attractor behavior is identified. By using a non-perturbative $\delta N$ analysis, we explicitly show that a highly non-Gaussian tail can be generated by a tiny upward step, even when the conventional nonlinearity parameters $f_{NL}$, $g_{NL}$, etc. remain small. With this example, we demonstrate for the first time the sensitive dependence of non-perturbative effects on the tail of probability distribution. Our scenario has an inconceivable application to primordial black holes by either significantly boosting their abundance or completely forbidding their appearance.Comment: 7 pages, 4 figure

Isospin dependence of projectile-like fragment production at intermediate energies

The cross sections of fragments produced in 140 $A$ MeV $^{40,48}$Ca + $^9$Be and $^{58,64}$Ni + $^9$Be reactions are calculated by the statistical abration-ablation(SAA) model and compared to the experimental results measured at the National Superconducting Cyclotron Laboratory (NSCL) at Michigan State University. The fragment isotopic and isotonic cross section distributions of $^{40}$Ca and $^{48}$Ca, $^{58}$Ni and $^{64}$Ni, $^{40}$Ca and $^{58}$Ni, and $^{48}$Ca and $^{64}$Ni are compared and the isospin dependence of the projectile fragmentation is studied. It is found that the isospin dependence decreases and disappears in the central collisions. The shapes of the fragment isotopic and isotonic cross section distributions are found to be very similar for symmetric projectile nuclei. The shapes of the fragment isotopic and isotonic distributions of different asymmetric projectiles produced in peripheral reactions are found very similar. The similarity of the distributions are related to the similar proton and neutron density distributions inside the nucleus in framework of the SAA model.Comment: 7 pages, 4 figures; to be published in Phys Rev

Limits on scalar-induced gravitational waves from the stochastic background by pulsar timing array observations

Recently, the NANOGrav, PPTA, EPTA, and CPTA collaborations independently reported their evidence of the Stochastic Gravitational Waves Background (SGWB). While the inferred gravitational-wave background amplitude and spectrum are consistent with astrophysical expectations for a signal from the population of supermassive black-hole binaries (SMBHBs), the search for new physics remains plausible in this observational window. In this work, we explore the possibility of explaining such a signal by the scalar-induced gravitational waves (IGWs) in the very early universe. We use a parameterized broken power-law function as a general description of the energy spectrum of the SGWB and fit it to the new results of NANOGrav, PPTA and EPTA. We find that this approach can put constraints on the parameters of IGW energy spectrum and further yield restrictions on various inflation models that may produce primordial black holes (PBHs) in the early universe, which is also expected to be examined by the forthcoming space-based GW experiments.Comment: 7 pages, 2 figures, update some reference

Heat Shock Protein 70 Protects the Heart from Ischemia/Reperfusion Injury through Inhibition of p38 MAPK Signaling.

BackgroundHeat shock protein 70 (Hsp70) has been shown to exert cardioprotection. Intracellular calcium ([Ca2+]i) overload induced by p38 mitogen-activated protein kinase (p38 MAPK) activation contributes to cardiac ischemia/reperfusion (I/R) injury. However, whether Hsp70 interacts with p38 MAPK signaling is unclear. Therefore, this study investigated the regulation of p38 MAPK by Hsp70 in I/R-induced cardiac injury.MethodsNeonatal rat cardiomyocytes were subjected to oxygen-glucose deprivation for 6 h followed by 2 h reoxygenation (OGD/R), and rats underwent left anterior artery ligation for 30 min followed by 30 min of reperfusion. The p38 MAPK inhibitor (SB203580), Hsp70 inhibitor (Quercetin), and Hsp70 short hairpin RNA (shRNA) were used prior to OGD/R or I/R. Cell viability, lactate dehydrogenase (LDH) release, serum cardiac troponin I (cTnI), [Ca2+]i levels, cell apoptosis, myocardial infarct size, mRNA level of IL-1β and IL-6, and protein expression of Hsp70, phosphorylated p38 MAPK (p-p38 MAPK), sarcoplasmic/endoplasmic reticulum Ca2+-ATPase2 (SERCA2), phosphorylated signal transducer and activator of transcription3 (p-STAT3), and cleaved caspase3 were assessed.ResultsPretreatment with a p38 MAPK inhibitor, SB203580, significantly attenuated OGD/R-induced cell injury or I/R-induced myocardial injury, as evidenced by improved cell viability and lower LDH release, resulted in lower serum cTnI and myocardial infarct size, alleviation of [Ca2+]i overload and cell apoptosis, inhibition of IL-1β and IL-6, and modulation of protein expressions of p-p38 MAPK, SERCA2, p-STAT3, and cleaved-caspase3. Knockdown of Hsp70 by shRNA exacerbated OGD/R-induced cell injury, which was effectively abolished by SB203580. Moreover, inhibition of Hsp70 by quercetin enhanced I/R-induced myocardial injury, while SB203580 pretreatment reversed the harmful effects caused by quercetin.ConclusionsInhibition of Hsp70 aggravates [Ca2+]i overload, inflammation, and apoptosis through regulating p38 MAPK signaling during cardiac I/R injury, which may help provide novel insight into cardioprotective strategies