Tucker Bilinear Attention Network for Multi-scale Remote Sensing Object Detection

Object detection on VHR remote sensing images plays a vital role in applications such as urban planning, land resource management, and rescue missions. The large-scale variation of the remote-sensing targets is one of the main challenges in VHR remote-sensing object detection. Existing methods improve the detection accuracy of high-resolution remote sensing objects by improving the structure of feature pyramids and adopting different attention modules. However, for small targets, there still be seriously missed detections due to the loss of key detail features. There is still room for improvement in the way of multiscale feature fusion and balance. To address this issue, this paper proposes two novel modules: Guided Attention and Tucker Bilinear Attention, which are applied to the stages of early fusion and late fusion respectively. The former can effectively retain clean key detail features, and the latter can better balance features through semantic-level correlation mining. Based on two modules, we build a new multi-scale remote sensing object detection framework. No bells and whistles. The proposed method largely improves the average precisions of small objects and achieves the highest mean average precisions compared with 9 state-of-the-art methods on DOTA, DIOR, and NWPU VHR-10.Code and models are available at https://github.com/Shinichict/GTNet.Comment: arXiv admin note: text overlap with arXiv:1705.06676, arXiv:2209.13351 by other author

Inhibition of PPARγ by BZ26, a GW9662 derivate, attenuated obesity-related breast cancer progression by inhibiting the reprogramming of mature adipocytes into to cancer associate adipocyte-like cells

Obesity has been associated with the development of 13 different types of cancers, including breast cancer. Evidence has indicated that cancer-associated adipocytes promote the proliferation, invasion, and metastasis of cancer. However, the mechanisms that link CAAs to the progression of obesity-related cancer are still unknown. Here, we found the mature adipocytes in the visceral fat of HFD-fed mice have a CAAs phenotype but the stromal vascular fraction of the visceral fat has not. Importantly, we found the derivate of the potent PPARγ antagonist GW9662, BZ26 inhibited the reprogramming of mature adipocytes in the visceral fat of HFD-fed mice into CAA-like cells and inhibited the proliferation and invasion of obesity-related breast cancer. Further study found that it mediated the browning of visceral, subcutaneous and perirenal fat and attenuated inflammation of adipose tissue and metabolic disorders. For the mechanism, we found that BZ26 bound and inhibited PPARγ by acting as a new modulator. Therefore, BZ26 serves as a novel modulator of PPARγ activity, that is, capable of inhibiting obesity-related breast cancer progression by inhibiting of CAA-like cell formation, suggesting that inhibiting the reprogramming of mature adipocytes into CAAs or CAA-like cells may be a potential therapeutic strategy for obesity-related cancer treatment

HI-Kyber: A novel high-performance implementation scheme of Kyber based on GPU

CRYSTALS-Kyber, as the only public key encryption (PKE) algorithm selected by the National Institute of Standards and Technology (NIST) in the third round, is considered one of the most promising post-quantum cryptography (PQC) schemes. Lattice-based cryptography uses complex discrete alogarithm problems on lattices to build secure encryption and decryption systems to resist attacks from quantum computing. Performance is an important bottleneck affecting the promotion of post quantum cryptography. In this paper, we present a High-performance Implementation of Kyber (named HI-Kyber) on the NVIDIA GPUs, which can increase the key-exchange performance of Kyber to the million-level. Firstly, we propose a lattice-based PQC implementation architecture based on kernel fusion, which can avoid redundant global-memory access operations. Secondly, We optimize and implement the core operations of CRYSTALS-Kyber, including Number Theoretic Transform (NTT), inverse NTT (INTT), pointwise multiplication, etc. Especially for the calculation bottleneck NTT operation, three novel methods are proposed to explore extreme performance: the sliced layer merging (SLM), the sliced depth-first search (SDFS-NTT) and the entire depth-first search (EDFS-NTT), which achieve a speedup of 7.5%, 28.5%, and 41.6% compared to the native implementation. Thirdly, we conduct comprehensive performance experiments with different parallel dimensions based on the above optimization. Finally, our key exchange performance reaches 1,664 kops/s. Specifically, based on the same platform, our HI-Kyber is 3.52$\times$ that of the GPU implementation based on the same instruction set and 1.78$\times$ that of the state-of-the-art one based on AI-accelerated tensor core

A riboflavin transporter deficiency presenting as pure red cell aplasia: a pediatric case report

IntroductionRiboflavin transporter deficiency (RTD) is a rare genetic disorder that affects riboflavin transport, leading to impaired red blood cell production and resulting in pure red cell aplasia. Recognizing and understanding its clinical manifestations, diagnosis, and management is important.Case presentationA 2-year-old patient presented with pure red cell aplasia as the primary symptom of RTD. After confirming the diagnosis, rapid reversal of anemia was achieved after high-dose riboflavin treatment.ConclusionRTD often has an insidious onset, and neurological symptoms appear gradually as the disease progresses, making it prone to misdiagnosis. Genetic testing and bone marrow biopsy can confirm the diagnosis

A bibliometric analysis of preoperative anxiety research (2001–2021)

Recently, mental health has received increasing attention, particularly preoperative anxiety, which constitutes a bad emotional experience for surgical patients. Many experts have studied preoperative anxiety in terms of its related risk factors, interventions, and postoperative effects; however, there has been no systematic analysis of published articles. This paper presents a bibliometric review of documents related to preoperative anxiety published between 2001 and 2021. A detailed data analysis of 1,596 publications was conducted using CiteSpace and VOSviewer. Since the 20th century, the field of preoperative anxiety has gradually developed; research began around 2000 and has made a huge leap forward since 2016. Developed countries, led by the United States, were the first to conduct research, but preoperative anxiety research in developing countries like Turkey and China has gradually increased and led to an irreplaceable contribution. Intervention has remained the main topic of preoperative anxiety research, and measures have developed from premedication to the provision of education and information. Moreover, the use of advanced equipment such as virtual reality has emerged with great popularity. Based on previous research, the application of virtual reality combined with pediatric patients will become a new research direction

The oyster genome reveals stress adaptation and complexity of shell formation

The Pacific oyster Crassostrea gigas belongs to one of the most species-rich but genomically poorly explored phyla, the Mollusca. Here we report the sequencing and assembly of the oyster genome using short reads and a fosmid-pooling strategy, along with transcriptomes of development and stress response and the proteome of the shell. The oyster genome is highly polymorphic and rich in repetitive sequences, with some transposable elements still actively shaping variation. Transcriptome studies reveal an extensive set of genes responding to environmental stress. The expansion of genes coding for heat shock protein 70 and inhibitors of apoptosis is probably central to the oyster's adaptation to sessile life in the highly stressful intertidal zone. Our analyses also show that shell formation in molluscs is more complex than currently understood and involves extensive participation of cells and their exosomes. The oyster genome sequence fills a void in our understanding of the Lophotrochozoa. © 2012 Macmillan Publishers Limited. All rights reserved

Research and Implementation of ε-SVR Training Method Based on FPGA

Online training of Support Vector Regression (SVR) in the field of machine learning is a computationally complex algorithm. Due to the need for multiple iterative processing in training, SVR training is usually implemented on computer, and the existing training methods cannot be directly implemented on Field-Programmable Gate Array (FPGA), which restricts the application range. This paper reconstructs the training framework and implementation without precision loss to reduce the total latency required for matrix update, reducing time consumption by 90%. A general ε-SVR training system with low latency is implemented on Zynq platform. Taking the regression of samples in two-dimensional as an example, the maximum acceleration ratio is 27.014× compared with microcontroller platform and the energy consumption is 12.449% of microcontroller. From the experiments for the University of California, Riverside (UCR) time series data set. The regression results obtain excellent regression effects. The minimum coefficient of determination is 0.996, and running time is less than 30 ms, which can meet the requirements of different applications for real-time regression