79 research outputs found

    The Relationship between Future Self-Continuity and Mobile Phone Dependence of College Students: Mediating Role of Self-Control

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    The problem of mobile phone dependence is becoming more and more serious. Therefore, it is very important to explore the causes of mobile phone dependence and its psychological mechanism. One of the important characteristics of mobile phone dependence is the loss of control, which shows that self-control is an important factor affecting mobile phone dependence. Self-continuity is closely related to cell phone dependence. Mobile phone addicts usually use mobile phones to temporarily relieve the pressure and negative emotions, but it will lead to more pressure and negative emotions in the future. In order to examine the situation of college students’ future self-continuity, self-control and mobile phone addiction as well as their relationships, especially mediating effect of self-control, a total of 482 college students were assessed with Future Self-Continuity Scale (FSC), Self-Control Scale (SCS), and Mobile Phone Dependency Index (MPAI). The results showed that: (1) The future self-continuity, self-control and mobile phone dependence of the college students in this study were all at a medium level, and there was no significant difference in demographic variables (such as gender, grade, etc.); (2) Both future self-continuity and self-control were negatively correlated with mobile phone dependence; (3) There was a significant positive correlation between future self-continuity and self-control; (4) Self-control played a partial mediating role between future self-continuity and mobile phone dependence. Therefore, improving self-continuity and self-control can be an effective way to intervene mobile phone dependence. In addition research implication, limitations and future directions were discussed

    The Influence of Emotional State on Mobile Phone Addiction Tendency in College Students: The Mediation Role of Regulatory Emotion Self-efficacy

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    In order to explore the situation of college students’ emotional state, regulatory emotion self-efficacy and mobile phone addiction tendency as well as their relationships, a total of 350 college students were assessed with Mobile Phone Addiction Tendency Scale (MPATS), Positive Affect and Negative Affect Scale (PANAS) and the Scale of Regulatory Emotional Self-efficacy (SRESE). The result showed that: (1) 40.86% of college students had the tendency of cell phone addiction, which was serious; 72.0% of college students were in a positive emotional state, 22% were in a negative emotional state; college students' regulatory emotion self-efficacy was in the middle level; (2) there was no gender, grade, major type, household registration type (rural and urban) and whether only child difference in mobile phone addiction tendency; (3) the positive emotions of college students were negatively correlated with the tendency of mobile phone addiction, while the negative emotions were positively correlated with the tendency of mobile phone addiction, and the positive emotion was positively correlated with regulatory emotional self-efficacy;(4) the regulatory emotion self-efficacy had a partial mediating effect between the positive emotions and mobile phone addiction tendency and had no mediating effect between the negative emotions and mobile phone addiction tendency.

    Liver fatty acid composition in mice with or without nonalcoholic fatty liver disease

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    <p>Abstract</p> <p>Background</p> <p>Nonalcoholic fatty liver disease (NAFLD) is one of the most frequent causes of abnormal liver function. Because fatty acids can damage biological membranes, fatty acid accumulation in the liver may be partially responsible for the functional and morphological changes that are observed in nonalcoholic liver disease. The aim of this study was to use gas chromatography-mass spectrometry to evaluate the fatty acid composition of an experimental mouse model of NAFLD induced by high-fat feed and CCl<sub>4 </sub>and to assess the association between liver fatty acid accumulation and NAFLD. C57BL/6J mice were given high-fat feed for six consecutive weeks to develop experimental NAFLD. Meanwhile, these mice were given subcutaneous injections of a 40% CCl<sub>4</sub>-vegetable oil mixture twice per week.</p> <p>Results</p> <p>A pathological examination found that NAFLD had developed in the C57BL/6J mice. High-fat feed and CCl<sub>4 </sub>led to significant increases in C14:0, C16:0, C18:0 and C20:3 (P < 0.01), and decreases in C15:0, C18:1, C18:2 and C18:3 (P < 0.01) in the mouse liver. The treatment also led to an increase in SFA and decreases in other fatty acids (UFA, PUFA and MUFA). An increase in the ratio of product/precursor n-6 (C20:4/C18:2) and n-3 ([C20:5+C22:6]/C18:3) and a decrease in the ratio of n-6/n-3 (C20:4/[C20:5+C22:6]) were also observed.</p> <p>Conclusion</p> <p>These data are consistent with the hypothesis that fatty acids are deranged in mice with non-alcoholic fatty liver injury induced by high-fat feed and CCl<sub>4</sub>, which may be involved in its pathogenesis and/or progression via an unclear mechanism.</p

    Genetic mapping of complex traits by minimizing integrated square errors

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    <p>Abstract</p> <p>Background</p> <p>Genetic mapping has been used as a tool to study the genetic architecture of complex traits by localizing their underlying quantitative trait loci (QTLs). Statistical methods for genetic mapping rely on a key assumption, that is, traits obey a parametric distribution. However, in practice real data may not perfectly follow the specified distribution.</p> <p>Results</p> <p>Here, we derive a robust statistical approach for QTL mapping that accommodates a certain degree of misspecification of the true model by incorporating integrated square errors into the genetic mapping framework. A hypothesis testing is formulated by defining a new test statistics - energy difference.</p> <p>Conclusions</p> <p>Simulation studies were performed to investigate the statistical properties of this approach and compare these properties with those from traditional maximum likelihood and non-parametric QTL mapping approaches. Lastly, analyses of real examples were conducted to demonstrate the usefulness and utilization of the new approach in a practical genetic setting.</p

    A statistical model for mapping morphological shape

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    <p>Abstract</p> <p>Background</p> <p>Living things come in all shapes and sizes, from bacteria, plants, and animals to humans. Knowledge about the genetic mechanisms for biological shape has far-reaching implications for a range spectrum of scientific disciplines including anthropology, agriculture, developmental biology, evolution and biomedicine.</p> <p>Results</p> <p>We derived a statistical model for mapping specific genes or quantitative trait loci (QTLs) that control morphological shape. The model was formulated within the mixture framework, in which different types of shape are thought to result from genotypic discrepancies at a QTL. The EM algorithm was implemented to estimate QTL genotype-specific shapes based on a shape correspondence analysis. Computer simulation was used to investigate the statistical property of the model.</p> <p>Conclusion</p> <p>By identifying specific QTLs for morphological shape, the model developed will help to ask, disseminate and address many major integrative biological and genetic questions and challenges in the genetic control of biological shape and function.</p

    EM Algorithm for Mapping Quantitative Trait Loci in Multivalent Tetraploids

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    Multivalent tetraploids that include many plant species, such as potato, sugarcane, and rose, are of paramount importance to agricultural production and biological research. Quantitative trait locus (QTL) mapping in multivalent tetraploids is challenged by their unique cytogenetic properties, such as double reduction. We develop a statistical method for mapping multivalent tetraploid QTLs by considering these cytogenetic properties. This method is built in the mixture model-based framework and implemented with the EM algorithm. The method allows the simultaneous estimation of QTL positions, QTL effects, the chromosomal pairing factor, and the degree of double reduction as well as the assessment of the estimation precision of these parameters. We used simulated data to examine the statistical properties of the method and validate its utilization. The new method and its software will provide a useful tool for QTL mapping in multivalent tetraploids that undergo double reduction
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