An investigation into the nutritional composition and cost of gluten-free versus regular food products in the UK

This is the peer reviewed version of the following article: Fry L., Madden A. M. & Fallaize R. (2017), 'An investigation into the nutritional composition and cost of gluten-free versus regular food products in the UK', Journal of Human Nutrition and Dietetics, Vol. 31 (1): 108-120, January 2018, doi: https://doi.org/10.1111/jhn.12502. Under embargo. Embargo end date: 29 August 2018. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.Background: The gluten-free (GF) food market has expanded considerably, although there is limited comparative evidence for the nutritional quality and cost of GF food products. The present study aims to compare the nutrient composition and cost of GF and gluten-containing (regular) foods across 10 food categories in the UK. Methods: Nutritional information and the cost of GF foods available in the UK (n = 679) and comparable regular foods (n = 1045) were systematically collected from manufacturer and supermarket websites. Foods were classified using UK front-of-pack labelling for content of fat, saturated fat, sugar and salt and nutrient content, and cost per 100 g were identified and compared between GF and regular foods. Results: Overall, more GF foods were classified as containing high and medium fat, saturated fat, sugar and salt than regular foods, although this was not universally consistent. More GF bread and flour products contained high fat and sugar, whereas fewer GF crackers contained high fat and sugar compared to regular foods. High salt content was found more frequently in GF than regular products. On average, GF products were 159% more expensive than regular (£0.44/100 g versus £1.14/100 g). GF items were also more likely to be lower in fibre and protein content than regular foods. Conclusions: Differences exist in the nutritional composition of GF and regular food. GF food is unlikely to offer healthier alternatives to regular foods, except for those who require a GF diet for medically diagnosed conditions, and it is associated with higher costs.Peer reviewe

Understanding variations in the built environment over time to inform longitudinal studies of young children's physical activity behaviour - The BEACHES Project

We know relatively little about the role the neighbourhood built environment plays in promoting young children’s physical activity, particularly its longitudinal effect either through repeated exposure to the same environment or through change in exposure by moving from one neighbourhood to another. This study characterised the neighbourhood environment of young children in the PLAYCE cohort study over three timepoints from 2015-2023. There were statistically significant differences in built environment attributes between timepoints and across socio-economic status, however they did not represent practically significant differences. These findings inform the analysis approach of subsequent research in the BEACHES Project, an international study examining the role of the built environment on child physical activity and obesity using multiple cohorts

The Provision Of Data From The COSMOS-UK Soil Moisture Monitoring Network

This paper describes the data available from COSMOS-UK, a new soil moisture monitoring network for the UK based on passive cosmic-ray moisture probes which are capable of measuring average soil water content over a circular footprint of around 350m in radius and depths of up to 0.5 m. Around 35 probes, with an associated array of meteorological and point soil moisture sensors, will be deployed across the UK in a network designed to best represent a range of soil and land cover types, complement existing scientific monitoring over a wide range of subject areas, and capture the variability in soil moisture over the country. Data will be automatically quality controlled and data streams will be openly and freely accessible via services and formats that conform to existing international standards, enabling integration with forecasting and data assimilation systems

Deriving household composition using population-scale electronic health record data—A reproducible methodology

BackgroundPhysical housing and household composition have an important role in the lives of individuals and drive health and social outcomes, and inequalities. Most methods to understand housing composition are based on survey or census data, and there is currently no reproducible methodology for creating population-level household composition measures using linked administrative data.MethodsUsing existing, and more recent enhancements to the address-data linkage methods in the SAIL Databank using Residential Anonymised Linking Fields we linked individuals to properties using the anonymised Welsh Demographic Service data in the SAIL Databank. We defined households, household size, and household composition measures based on adult to child relationships, and age differences between residents to create relative age measures.ResultsTwo relative age-based algorithms were developed and returned similar results when applied to population and household-level data, describing household composition for 3.1 million individuals within 1.2 million households in Wales. Developed methods describe binary, and count level generational household composition measures.ConclusionsImproved residential anonymised linkage field methods in SAIL have led to improved property-level data linkage, allowing the design and application of household composition measures that assign individuals to shared residences and allow the description of household composition across Wales. The reproducible methods create longitudinal, household-level composition measures at a population-level using linked administrative data. Such measures are important to help understand more detail about an individual's home and area environment and how that may affect the health and wellbeing of the individual, other residents, and potentially into the wider community

Trajectories in chronic disease accrual and mortality across the lifespan in Wales, UK (2005–2019), by area deprivation profile: linked electronic health records cohort study on 965,905 individuals

Background: Understanding and quantifying the differences in disease development in different socioeconomic groups of people across the lifespan is important for planning healthcare and preventive services. The study aimed to measure chronic disease accrual, and examine the differences in time to individual morbidities, multimorbidity, and mortality between socioeconomic groups in Wales, UK.Methods: Population-wide electronic linked cohort study, following Welsh residents for up to 20 years (2000-2019). Chronic disease diagnoses were obtained from general practice and hospitalisation records using the CALIBER disease phenotype register. Multi-state models were used to examine trajectories of accrual of 132 diseases and mortality, adjusted for sex, age and area-level deprivation. Restricted mean survival time was calculated to measure time spent free of chronic disease(s) or mortality between socioeconomic groups.Findings: In total, 965,905 individuals aged 5-104 were included, from a possible 2.9 m individuals following a 5-year clearance period, with an average follow-up of 13.2 years (12.7 million person-years). Some 673,189 (69.7%) individuals developed at least one chronic disease or died within the study period. From ages 10 years upwards, the individuals living in the most deprived areas consistently experienced reduced time between health states, demonstrating accelerated transitions to first and subsequent morbidities and death compared to their demographic equivalent living in the least deprived areas. The largest difference were observed in 10 and 20 year old males developing multimorbidity (-0.45 years (99% CI: -0.45, -0.44)) and in 70 year old males dying after developing multimorbidity (-1.98 years (99% CI: -2.01, -1.95)).Interpretation: This study adds to the existing literature on health inequalities by demonstrating that individuals living in more deprived areas consistently experience accelerated time to diagnosis of chronic disease and death across all ages, accounting for competing risks

Dynamic real-time hydrological status monitoring in the UK

A 'display' at the EGU General Assembly 2020. Understanding the current hydro-meteorological situation is critical to manage extreme events and water resources. The UK Water Resources Portal (UKWRP) has been developed to enable dynamic, interactive, real-time access to hydro-meteorological data, including catchment daily rainfall, real-time daily mean river flows, real-time soil moisture data from COSMOS-UK and standardised climate indices. Users can access and view data at the field, grid cell and catchment scale enabling holistic assessments of the hydro-meteorological status at a range of spatial scales. The portal offers a way of exploring the full range of river flow and rainfall variability, including comparing current conditions to those in the past, from droughts to floods. A variety of different plotting capabilities mean users can view and explore data in different ways depending on their requirements. The UKWRP can be used alone or alongside other resources such as: the UK Hydrological Outlook seasonal forecasts, the Hydrological Summary for the UK and Environment Agency Water Situation Reports, to manage water resources, to plan and prepare for extreme events, and to understand and communicate their severity. The UKWRP enables all water users, from farmers, to water companies to members of the general public to view and explore the data used by regulators to manage water supplies. Equalising access to data can be extremely powerful; for example in the case of farmers, it means they can easily view real time river flows in relation to conditions on their licence using the same data used by regulators to impose abstraction restrictions during a drought. Here we present the stakeholder engagement story of how and why the UKWRP was developed, demonstrate the capability of the UKWRP to monitor the hydrological situation in real time, and present plans for its future development, such as the addition of more indicators and indices

Associations between the Home Physical Environment and Children’s Home-Based Physical Activity and Sitting

It is important to understand the correlates of children’s physical activity (PA) and sitting at home, where children spend significant time. The home social environment has an important influence; however, much less is known about the home physical environment. Therefore, the study aimed to assess relationships between the physical environment and children’s sitting and PA at home. In total, 235 child-parent dyads were included in the analyses. Children spent 67% of their time at home sitting. Linear regression analyses examined associations between physical home environmental factors obtained via an audit and children’s (55% girl, 10.2 ± 0.7) objective PA and sitting at home. Following adjustment for socio-demographics and social environmental factors, an open plan living area (OPLA), musical instrument accessibility and availability, and perceived house size were negatively and positively associated, whereas media equipment accessibility and availability was positively and negatively associated with sitting and standing, respectively. Additionally, an OPLA was positively associated with total and moderate-to-vigorous PA. Furthermore, sitting breaks were positively associated with objective garden size and negatively associated with digital TV. The physical home environment may have an important influence on children’s sitting, standing and PA at home; therefore, interventions that target this environment are needed

Dynamic high resolution hydrological status monitoring in real-time: the UK Water Resources Portal

Understanding the current hydro-meteorological situation is critical to manage extreme events and water resources. The United Kingdom Water Resources Portal (UKWRP) has been developed to enable dynamic, interactive access to hydro-meteorological data across the United Kingdom, including catchment daily rainfall (near), real-time daily mean river flows, groundwater levels, real-time soil moisture data, and standardised climate indices. The UKWRP offers a way of exploring the full range of river flow and rainfall variability, including comparing current conditions to those in the past, from droughts to floods. A variety of different plotting capabilities mean users can view and explore data in different ways depending on their requirements. Here we discuss the mechanisms and the engagement undertaken to develop the UKWRP, in addition to the technical issues and solutions of bringing multiple data sources and types together, how the data are processed, stored and published to deliver an integrated tool for water resources management. The UKWRP enables all water users–from farmers, to water companies to members of the general public–to view and explore the data used by regulators to manage water supplies. We demonstrate how the UKWRP can be used to monitor the hydrological situation, using recent examples of both floods and droughts, and enables consistent messaging and universal access to data and information. Finally, we discuss the decisions the information provided in the UKWRP can support, and possible future developments. The UKWRP is aimed at the United Kingdom water research and management community, but we envisage that the Portal (and the development pathway and technical solutions reported here) could provide a useful exemplar for similar systems in other international settings

Risk of thrombocytopenic, haemorrhagic and thromboembolic disorders following COVID-19 vaccination and positive test: a self-controlled case series analysis in Wales

There is a need for better understanding of the risk of thrombocytopenic, haemorrhagic, thromboembolic disorders following first, second and booster vaccination doses and testing positive for SARS-CoV-2. Self-controlled cases series analysis of 2.1 million linked patient records in Wales between 7th December 2020 and 31st December 2021. Outcomes were the first diagnosis of thrombocytopenic, haemorrhagic and thromboembolic events in primary or secondary care datasets, exposure was defined as 0–28 days post-vaccination or a positive reverse transcription polymerase chain reaction test for SARS-CoV-2. 36,136 individuals experienced either a thrombocytopenic, haemorrhagic or thromboembolic event during the study period. Relative to baseline, our observations show greater risk of outcomes in the periods post-first dose of BNT162b2 for haemorrhagic (IRR 1.47, 95%CI: 1.04–2.08) and idiopathic thrombocytopenic purpura (IRR 2.80, 95%CI: 1.21–6.49) events; post-second dose of ChAdOx1 for arterial thrombosis (IRR 1.14, 95%CI: 1.01–1.29); post-booster greater risk of venous thromboembolic (VTE) (IRR-Moderna 3.62, 95%CI: 0.99–13.17) (IRR-BNT162b2 1.39, 95%CI: 1.04–1.87) and arterial thrombosis (IRR-Moderna 3.14, 95%CI: 1.14–8.64) (IRR-BNT162b2 1.34, 95%CI: 1.15–1.58). Similarly, post SARS-CoV-2 infection the risk was increased for haemorrhagic (IRR 1.49, 95%CI: 1.15–1.92), VTE (IRR 5.63, 95%CI: 4.91, 6.4), arterial thrombosis (IRR 2.46, 95%CI: 2.22–2.71). We found that there was a measurable risk of thrombocytopenic, haemorrhagic, thromboembolic events after COVID-19 vaccination and infection