An Analysis of Expansion and Relocation Sites for Major League Soccer

This research develops a model of optimal locations for Major League Soccer teams and investigates the important underlying factors.soccer; MLS; regression; probit; demand; location

An Analysis of Expansion and Relocation Sites for Major League Soccer

This research develops a model of optimal locations for Major League Soccer teams and investigates the important underlying factors

Asymmetrien in der Neuen Ökonomischen Geographie : Modelle, Simulationsmethoden und wirtschaftspolitische Diskussion = Asymmetries in new economic geography : models, simulation methods and economic discussion

The new economic geography explains agglomerations based on a microeconomic general equilibrium model, witch is usually assumed to be symmetric in the sense, that regions are of the same size and transport costs and expenditure shares are the same. As a result, the models can explain why an agglomeration occurs, but not in witch region. This book modifies three of the most influential models of the new economic geography and assumes various asymmetries. It compares the results to the symmetric cases. Not only theoretical aspects but also methods of simulation are discussed in detail. This methods can be applied to a wide variety of models. To show the political implications of the theoretical results, one of the asymmetric models is applied to the economical development in germany after reunification. The model is able to explain the persistent difference in wages between east and west and the simultaneous incomplete agglomeration in the west.new economic geography, methods of simulation, agglomeration, regional development

Kim Adams : Curbing Machine and Gift Machine

According to Frohwerk, Adam's complex assemblages of mass-produced objects decode the psychological and sociological processes of commodity exchange. Biographical notes

Das Cluster-Modell bei sektoral unterschiedlichen Transportkosten

Das Cluster-Modell von Krugman und Venables (1996) erklärt im Rahmen der Neuen Ökonomischen Geographie die Bildung von Agglomerationen bei regional immobilen Arbeitskräften. Die resultierenden Gleichgewichte hängen von der Höhe der Transportkosten ab, die allerdings in beiden Sektoren als gleich hoch unterstellt werden. Der vorliegende Beitrag erweitert dieses Modell um die Möglichkeit sektoral unterschiedlicher Transportkosten. Da eine analytische Lösung nichtmöglich ist, wird eine geeignete Simulationsmethode entwickelt. Anhand von Abbildungen wird dargestellt, welche Gleichgewichte sich bei verschiedenen Werten für die beiden Transportkostensätze ergeben.

Hors des sentiers battus = Off the Beaten Track

Defining Winnipeg as representative of the postmodern condition, the authors underline the role of artist-run centres in the development of regional cultures and a multiplicity of practices. Includes descriptions of the artists' works. Biographical notes. 3 bibl. ref

The structural and functional importance of the CD34 family in lung function and vascular cell biology

Despite the widespread use of CD34-family sialomucins (CD34, podocalyxin (Podxl) and endoglycan) as vascular endothelial cell (EC) markers, there is remarkably little known of their role in vascular development and functions with the exception of vessel lumen formation in the developing mouse embryo (Podxl) and vessel patency during tumor angiogenesis and inflammation (CD34). Because germ-line deletion of Podxl in mice causes perinatal death, we generated mice that conditionally delete Podxl in vascular endothelial cells (PodxlΔEC mice) to study the role of podocalyxin in adult mouse vessels. Although PodxlΔEC adult mice are viable and thrive, we discovered increased basal and inflammationinduced pulmonary vascular permeability. Furthermore, PodxlΔEC mouse adult lungs display airspace enlargement with increased collagen deposition and exhibit a gene expression profile similar to regenerating lung. To study whether endothelial cell morphology influences the defective lung architecture and the vascular permeability phenotype in PodxlΔEC mice, we isolated primary vascular ECs from lung tissue. PodxlΔEC ECs display enhanced adhesion to fibronectin (FN) in a static adhesion assay. When plated on matrix-coated transwells, PodxlΔEC EC spread normally on FN but display defective spreading on laminin and collagen I. Thus, expression of Podxl in EC is required for normal lung architecture and function in adult mice and adhesion of EC to extracellular matrix components. Although its expression has not been well characterized, in humans, endoglycan expression has been reported in vascularized tissues. In mouse blood vessels, we showed that vascular smooth muscle cells (vSMC), but not EC, express the highest levels of endoglycan. Using a mouse aortic smooth muscle line (MOVAS-1) we found that forced expression of endoglycan enhances basal but not platelet derived growth factor (PDGF)ββ-dependent vSMC migration in vitro. Further studies to understand the role of endoglycan in primary vSMC showed that endoglycan is upregulated with differentiation to a contractile phenotype, but is not influenced by inflammatory stimuli or mitogenic factors. The findings of this thesis suggest that the CD34 family regulates vascular development and function with a role for podocalyxin in EC-matrix adhesion relevant to normal lung function and a role for endoglycan in SMC differentiation and migration.Medicine, Faculty ofMedicine, Department ofExperimental Medicine, Division ofGraduat