81 research outputs found
Interactions between magnetic nanoparticles and model lipid bilayers—Fourier transformed infrared spectroscopy (FTIR) studies of the molecular basis of nanotoxicity
The toxicity of nanoparticles (nanotoxicity) is often associated with their
interruption of biological membranes. The effect of polymer-coated magnetic
nanoparticles (with different Fe3O4 core sizes and different polymeric
coatings) on a model biological membrane system of vesicles formed by
dimyristoylphosphatidylcholine (DMPC) was studied. Selected magnetic
nanoparticles with core sizes ranging from 3 to 13 nm (in diameter) were
characterised by transmission electron microscopy. Samples with 10% DMPC and
different nanoparticle concentrations were studied by attenuated total
reflectance—Fourier transform infrared spectroscopy to establish the influence
of nanoparticles on the phase behaviour of model phospholipid systems
A new crystalline phase of L-alpha-dipalmitoyl phosphatidylcholine monohydrate.
A new phase transition of L-alpha-dipalmitoyl phosphatidylcholine (DPPC) monohydrate from the "biaxial" phase to a crystalline phase (C phase) has been found at 71 degrees C by means of infrared attenuated total reflection (IR-ATR) spectroscopy. The transition is characterized by drastic conformational changes in the glycerophosphorylcholine moiety, which led on the one hand to an alignment of the turn near the ester group in the hydrocarbon chain at glycerol C(2) position. On the other hand a uniform conformation of the glycerophosphorylcholine moiety is found to be typical for the C phase, in contrast to nonuniform head group conformations of DPPC in other regions of the DPPC/water phase diagram investigated so far
Structure-activity relationship in vinculin: an IR/attenuated total reflection spectroscopic and film balance study.
Structural investigation of biological material in aqueous environment by means of infrared-ATR spectroscopy
A new phase transition of L-?-dipalmitoyl lecithin monohydrate leading to uniform head group conformation
Modification of Time-Resolved Step-Scan and Rapid-Scan FTIR Spectroscopy for Modulation Spectroscopy in the Frequency Range from Hz to kHz
this paper are more transparent and better accessible for the user and provide additional timedependent information (time domain, e.g. the time course of the absorbance during the stimulus period). 0.000 0.005 0.010 0.015 Phase lag /deg Frequency of sample modulation /Hz 1 10 100 1000 10000 45 90 135 180 22
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