1,802 research outputs found

    Electron Energy-Loss Spectroscopy: A versatile tool for the investigations of plasmonic excitations

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    The inelastic scattering of electrons is one route to study the vibrational and electronic properties of materials. Such experiments, also called electron energy-loss spectroscopy, are particularly useful for the investigation of the collective excitations in metals, the charge carrier plasmons. These plasmons are characterized by a specific dispersion (energy-momentum relationship), which contains information on the sometimes complex nature of the conduction electrons in topical materials. In this review we highlight the improvements of the electron energy-loss spectrometer in the last years, summarize current possibilities with this technique, and give examples where the investigation of the plasmon dispersion allows insight into the interplay of the conduction electrons with other degrees of freedom

    Efficient and spectrally bright source of polarization-entangled photons

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    We demonstrate an efficient fiber-coupled source of nondegenerate polarization entangled photons at 795 and 1609 nm using bidirectionally pumped parametric down-conversion in bulk periodically poled lithium niobate. The single-mode source has an inferred bandwidth of 50 GHz and a spectral brightness of 300 pairs/s/GHz/mW of pump power that is suitable for narrowband applications such as entanglement transfer from photonic to atomic qubits.Comment: 8 pages, 7 figures, submitted to Phys. Rev.

    Treewidth, Pathwidth and Cospan Decompositions

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    We will revisit the categorical notion of cospan decompositions of graphs and compare it to the well-known notions of path decomposition and tree decomposition from graph theory. More specifically, we will define several types of cospan decompositions with appropriate width measures and show that these width measures coincide with pathwidth and treewidth. Such graph decompositions of small width are used to efficiently decide graph properties, for instance via graph automata

    Development of new advertising channels : „WelectGo“ - Advertising instead of train ticket

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    Im Rahmen der Bachelorarbeit werden klassische sowie neue Medienkanäle dargestellt, erklärt und analysiert. Sie gibt Handlungshinweise, die Unternehmen zu einem erfolgreichen Markenauftritt verhelfen sollen. Die erste Hälfte der Arbeit beschäftigt sich mit den klassischen Medien wie Print- oder digitalen Medien. In der zweiten Hälfte wird eine neue Form des Marketings vorgestellt und anhand eines Beispiels, der App „WelectGo“, näher erläutert

    Efficient generation of tunable photon pairs at 0.8 and 1.6 micrometer

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    We demonstrate efficient generation of collinearly propagating, highly nondegenerate photon pairs in a periodically-poled lithium niobate cw parametric downconverter with an inferred pair generation rate of 1.4*10^7/s/mW of pump power. Detection of an 800-nm signal photon triggers a thermoelectrically-cooled 20%-efficient InGaAs avalanche photodiode for the detection of the 1600-nm conjugate idler photon. Using single-mode fibers as spatial mode filters, we obtain a signal-conditioned idler-detection probability of about 3.1%.Comment: 8 pages, 3 figure

    Processing of the Terminal Alpha-1,2-Linked Mannose Residues From Oligomannosidic N-Glycans Is Critical for Proper Root Growth

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    N-glycosylation is an essential protein modification that plays roles in many diverse biological processes including protein folding, quality control and protein interactions. Despite recent advances in characterization of the N-glycosylation and N-glycan processing machinery our understanding of N-glycosylation related processes in plant development is limited. In Arabidopsis thaliana, failure of mannose trimming from oligomannosidic N-glycans in the endoplasmic reticulum (ER) and cis/medial-Golgi leads to a defect in root development in the mns123 triple mutant. Here, we show that the severe root phenotype of mns123 is restored in asparagine-linked glycosylation (ALG)-deficient plants with distinct defects in the biosynthesis of the lipid-linked oligosaccharide precursor. The root growth of these ALG-deficient plants is not affected by the α-mannosidase inhibitor kifunensine. Genetic evidence shows that the defect is uncoupled from the glycan-dependent ER-associated degradation (ERAD) pathway that removes misfolded glycoproteins with oligomannosidic N-glycans from the ER. Restoration of mannose trimming using a trans-Golgi targeted α-mannosidase suppresses the defect of mns123 roots. These data suggest that processing of terminal mannose residues from oligomannosidic N-glycans is important for an unknown late-Golgi or post-Golgi process that is implicated in proper root formation

    A Novel Seeding and Conditioning Bioreactor for Vascular Tissue Engineering

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    Multiple efforts have been made to develop small-diameter tissue engineered vascular grafts using a great variety of bioreactor systems at different steps of processing. Nevertheless, there is still an extensive need for a compact all-in-one system providing multiple and simultaneous processing. The aim of this project was to develop a new device to fulfill the major requirements of an ideal system that allows simultaneous seeding, conditioning, and perfusion. The newly developed system can be actuated in a common incubator and consists of six components: a rotating cylinder, a pump, a pulse generator, a control unit, a mixer, and a reservoir. Components that are in direct contact with cell media, cells, and/or tissue allow sterile processing. Proof-of-concept experiments were performed with polyurethane tubes and collagen tubes. The scaffolds were seeded with fibroblasts and endothelial cells that were isolated from human saphenous vein segments. Scanning electron microscopy and immunohistochemistry showed better seeding success of polyurethane scaffolds in comparison to collagen. Conditioning of polyurethane tubes with 100 dyn/cm2 resulted in cell detachments, whereas a moderate conditioning program with stepwise increase of shear stress from 10 to 40 dyn/cm2 induced a stable and confluent cell layer. The new bioreactor is a powerful tool for quick and easy testing of various scaffold materials for the development of tissue engineered vascular grafts. The combination of this bioreactor with native tissue allows testing of medical devices and medicinal substances under physiological conditions that is a good step towards reduction of animal testing. In the long run, the bioreactor could turn out to produce tissue engineered vascular grafts for human applications “at the bedside”
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