A Community of Me: The Role of Participation Allocation in Determining the Effectiveness of Consumer Empowerment Strategies

Past research has shown that consumers who are empowered to select what products a firm offers show a stronger demand for the selected product than non-empowered consumers due to an increase in psychological ownership of the product. However, this research has not systematically examined what influence the amount of participation an individual perceives themselves as having in a collaborative design process has on their degree of psychological ownership.  This article investigates the effect that consumers’ perceived amount of participation has on psychological ownership of a product and whether reference group dynamics impact this effect. Two studies demonstrate that any perceived amount of participation, whether large, small, or ambiguous, equally increases consumers’ psychological ownership of a product, future loyalty intentions toward the company, and underlying demand for the product, compared to attributing full influence to a single “winner”, which is equal to allocating no participation to consumers. In cases of non-empowering participation allocation strategies, psychological ownership increases when in-group members are perceived to have a significant influence on the product while future loyalty intentions toward the company decrease when dissociative out-group members are perceived to have a large influence. This effect is moderated by consumer’s degree of association with their in-group

55-year-old Male with Exertional Dyspnea

Introduction: Dyspnea is a common presenting complaint for many patients in the emergency department.Case Presentation: A 55-year-old man with type I diabetes presented to the emergency department with one month of intermittent palpitations and dyspnea. His lungs were clear to auscultation, and his chest radiograph was normal.Discussion: This case takes the reader through the differential diagnosis and systematic work-up of dyspnea with discussion of the diagnostic study, which ultimately led to this patient’s diagnosis and successful treatment

FACIAL EXPRESSION RECOGNITION DEFICITS IN AUTISM SPECTRUM DISORDER

Autism Spectrum Disorders (ASD) are an umbrella term for lifelong neurobehavioral disorders characterized by a set of social (verbal and nonverbal) communication challenges and behaviors and restricted, repetitive behaviors. Emotions serve many functions, but primarily they help with the appraisal of stimuli and driving of responses. Emotional processing and facial recognition are integral abilities that influence the acquisition of social skills. For individuals with ASD, it is hypothesized that facial recognition deficits contribute to social communication traits. The bulk of previously conducted research has utilized static images of facial expressions. This study utilized videos of spontaneous expressions. Participants were tasked with labeling facial expression valence. Neither a participants’ level of ASD severity or their age were significant predictors of facial expression valence labeling. Furthermore, neither independent variable, age or ASD severity level, had a significant impact on their overall accuracy of labeling facial expression valence. On average, videos of a happy facial expression were most correctly labeled, while sad faces on average were the most incorrectly labeled videos

The Knowledge Object Reference Ontology (KORO): A formalism to support management and sharing of computable biomedical knowledge for learning health systems

IntroductionHealth systems are challenged by care underutilization, overutilization, disparities, and related harms. One problem is a multiyear latency between discovery of new best practice knowledge and its widespread adoption. Decreasing this latency requires new capabilities to better manage and more rapidly share biomedical knowledge in computable forms. Knowledge objects package machineâ executable knowledge resources in a way that easily enables knowledge as a service. To help improve knowledge management and accelerate knowledge sharing, the Knowledge Object Reference Ontology (KORO) defines what knowledge objects are in a formal way.MethodsDevelopment of KORO began with identification of terms for classes of entities and for properties. Next, we established a taxonomical hierarchy of classes for knowledge objects and their parts. Development continued by relating these parts via formally defined properties. We evaluated the logical consistency of KORO and used it to answer several competency questions about parthood. We also applied it to guide knowledge object implementation.ResultsAs a realist ontology, KORO defines what knowledge objects are and provides details about the parts they have and the roles they play. KORO provides sufficient logic to answer several basic but important questions about knowledge objects competently. KORO directly supports creators of knowledge objects by providing a formal model for these objects.ConclusionKORO provides a formal, logically consistent ontology about knowledge objects and their parts. It exists to help make computable biomedical knowledge findable, accessible, interoperable, and reusable. KORO is currently being used to further develop and improve computable knowledge infrastructure for learning health systems.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/143591/1/lrh210054_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/143591/2/lrh210054.pd

National Assessment Program: ICT Literacy 2022: Public report

This public report documents the findings of the sixth National Assessment Program ICT Literacy (NAP–ICT Literacy) assessment cycle. In reporting national key performance measures (KPMs) of Australian students’ ICT literacy, the NAP–ICT Literacy assessment provides a way to monitor progress towards the Alice Springs (Mparntwe) Education Goals for Young Australians. Goal 2 of the Alice Springs (Mparntwe) Education Declaration is that “all young Australians become confident and creative individuals, successful lifelong learners, and active and informed members of the community” (Education Council 2019, p. 6). The elaboration of this goal highlights the importance of young Australians’ digital and ICT literacy in a rapidly evolving technological landscape and establishes the context and rationale for reporting on student achievement and progress in this area. For NAP–ICT Literacy 2022, ICT literacy is defined as “the ability to use ICT appropriately and safely to access, manage and evaluate information; develop new understandings; apply computational, design and systems thinking to create solutions; communicate and collaborate with others; and engage productively with emerging and future technologies” (ACARA 2020, p. 13). The NAP–ICT Literacy assessment instrument requires students to apply their ICT knowledge within real-world contexts that represent the 4 strands and integrated aspects outlined in the NAP–ICT Literacy Assessment Framework. These are: understanding ICT and digital systems, investigating and planning solutions with ICT, implementing and evaluating digital solutions, and applying safe and ethical protocols and practices when using ICT

Dual Navigation of Computerized Self-Administered Questionnaires and Organizational Records

This research explored dual navigation between organizational records and a computerized self-administered questionnaire. Two alternative interface designs for on-line questionnaire presentation were investigated. The form-based version of the questionnaire was divided into sections by question topic and each section was displayed as a single web page. In the item-based version, each question item was displayed individually on the screen. The navigational data collected was used to examine how participants moved between the organizational records and the questionnaire items as they completed the computerized questionnaire. Along with the navigational data, responses from pre- and post- questionnaires were analyzed. There were no significant differences in terms of accuracy, completion time, and ratings given in the pre- and post- questionnaires. However, there were significantly different navigational patterns between the two groups. Respondents in the form-based group tended to answer questions in more of a non-linear sequence. Additionally, the item-based group had more organizational record to organizational record traversals while the form-based group had more questionnaire item to questionnaire item traversals. Keywords : Questionnaires, Surveys, User Interface, World Wide Web, CSAQ, Navigation, Break-Dancing (Also corss-referenced as HCIL-TR-2000-22) (Also cross-referenced as UMIACS-TR-2000-71

Validation of high gradient magnetic field based drug delivery to magnetizable implants under flow

IEEE Transactions on Biomedical Engineering, 55(2): pp. 643-649.The drug-eluting stent’s increasingly frequent occurrence late stage thrombosis have created a need for new strategies for intervention in coronary artery disease. This paper demonstrates further development of our minimally invasive, targeted drug delivery system that uses induced magnetism to administer repeatable and patient specific dosages of therapeutic agents to specific sites in the human body. Our first aim is the use of magnetizable stents for the prevention and treatment of coronary restenosis; however, future applications include the targeting of tumors, vascular defects, and other localized pathologies. Future doses can be administered to the same site by intravenous injection. This implant-based drug delivery system functions by placement of a weakly magnetizable stent or implant at precise locations in the cardiovascular system, followed by the delivery of magnetically susceptible drug carriers. The stents are capable of applying high local magnetic field gradients within the body, while only exposing the body to a modest external field. The local gradients created within the blood vessel create the forces needed to attract and hold drug-containing magnetic nanoparticles at the implant site. Once these particles are captured, they are capable of delivering therapeutic agents such as antineoplastics, radioactivity, or biological cells

Heterochromatin Controls γH2A Localization in Neurospora crassa

In response to genotoxic stress, ATR and ATM kinases phosphorylate H2A in fungi and H2AX in animals on a C-terminal serine. The resulting modified histone, called γH2A, recruits chromatin-binding proteins that stabilize stalled replication forks or promote DNA double-strand-break repair. To identify genomic loci that might be prone to replication fork stalling or DNA breakage in Neurospora crassa, we performed chromatin immunoprecipitation (ChIP) of γH2A followed by next-generation sequencing (ChIP-seq). γH2A-containing nucleosomes are enriched in Neurospora heterochromatin domains. These domains are comprised of A·T-rich repetitive DNA sequences associated with histone H3 methylated at lysine-9 (H3K9me), the H3K9me-binding protein heterochromatin protein 1 (HP1), and DNA cytosine methylation. H3K9 methylation, catalyzed by DIM-5, is required for normal γH2A localization. In contrast, γH2A is not required for H3K9 methylation or DNA methylation. Normal γH2A localization also depends on HP1 and a histone deacetylase, HDA-1, but is independent of the DNA methyltransferase DIM-2. γH2A is globally induced in dim-5 mutants under normal growth conditions, suggesting that the DNA damage response is activated in these mutants in the absence of exogenous DNA damage. Together, these data suggest that heterochromatin formation is essential for normal DNA replication or repair