Short-term outcome in infants born after PPROM categorized according to diagnosis of amniotic infection syndrome (AIS).

<p>p-values are derived from Fisher´s exact test or Mann-Whitney-U-test if indicated (*)</p><p>Short-term outcome in infants born after PPROM categorized according to diagnosis of amniotic infection syndrome (AIS).</p

Multivariable logistic regression analysis for mortality and morbidities including well known-risk factors.

<p>Multivariable logistic regression analysis for mortality and morbidities including well known-risk factors.</p

Treatment differences of VLBW cohort categorized according to PPROM.

<p>p-values are derived from Fisher´s exact test or Mann-Whitney-U-test if indicated (*)</p><p>Treatment differences of VLBW cohort categorized according to PPROM.</p

Clinical characteristics of VLBW cohort categorized according to PPROM.

<p>p-values are derived from Fisher´s exact test or Mann-Whitney-U-test if indicated (*)</p><p>Clinical characteristics of VLBW cohort categorized according to PPROM.</p

Short-term outcomes categorized according to PPROM.

<p>p-values are derived from Fisher´s exact test or Mann-Whitney-U-test if indicated (*)</p><p>Short-term outcomes categorized according to PPROM.</p

Pathogenic spectrum of blood-culture proven sepsis episodes.

*<p>Estimate: estimated risk for specific pathogen/100 cases of blood-culture proven sepsis.</p

Outcome of patients in microclusters of blood-culture proven sepsis.

<p><b>Legend:</b> IVH intraventricular haemorrhage; Surgery for PDA Patent Ductus arteriosus, NEC necrotizing enterocolitis, FIP focal intestinal perforation, ROP retinopathy of prematurity (kryo- or laser therapy); BPD bronchopulmonary dysplasia; severe complication: IVH grade IV, posthaemorrhagic hydrocephalus with need for VP shunt, periventricular leukomalacia, surgery for NEC/FIP or ROP and BPD;</p><p>p-values were derived from chi-square test if not otherwise indicated (* Mann-Whitney-U test comparing linked cases vs. first patient in cluster.</p

Clinical characteristics of the VLBW cohort stratified to occurrence of late-onset sepsis (LOS).

<p><b>Legend:</b> PPROM Preterm premature rupture of membranes, C/section Caesarean section, SGA small-for-gestational-age (<10th Voigt percentile).</p><p># p-values were derived from chi-square test if not otherwise indicated (* Mann-Whitney-U test).</p