Comparison of Two Azithromycin Distribution Strategies for Controlling Trachoma in Nepal

OBJECTIVE: The study compares the effectiveness of two strategies for distributing azithromycin in an area with mild-to-moderate active trachoma in Nepal. METHODS: The two strategies investigated were the use of azithromycin for 1) mass treatment of all children, or 2) targeted treatment of only those children who were found to be clinically active, as well as all members of their household. FINDINGS: Mass treatment of children was slightly more effective in terms of decreasing the prevalence of clinically active trachoma (estimated by clinical examination) and of chlamydial infection (estimated by DNA amplification tests), although neither result was statistically significant. CONCLUSION: Both strategies appeared to be effective in reducing the prevalence of clinically active trachoma and infection six months after the treatment. Antibiotic treatment reduced the prevalence of chlamydial infection more than it did the level of clinically active trachoma

Carbohydrate and amino acid metabolism in fasting and aestivating African lungfish (Protopterus dolloi)

10.1016/j.cbpa.2008.06.003Comparative Biochemistry and Physiology - A Molecular and Integrative Physiology151185-92CBPA

Lipid, ketone body and oxidative metabolism in the African lungfish, Protopterus dolloi following 60 days of fasting and aestivation

10.1016/j.cbpa.2008.06.004Comparative Biochemistry and Physiology - A Molecular and Integrative Physiology151193-101CBPA

eHealth und Pflege: eine kritische Einschätzung

Die digitale Transformation trifft uns im «Epizentrum» unserer pflegerischen Tätigkeit, nämlich der Mensch-zu-Mensch-Beziehung. Wir blicken auf Errungenschaften und Vorteile, aber auch auf Aspekte, die im Praxisalltag nach wie vor problematisch sind. Wir zeigen in folgendem Artikel, wie wir die digitale Transformation im Sinne unserer Profession bestmöglich gestalten und nutzen können

Reliability and construct validity of the Dutch psychopathy checklist: youth version: findings from a sample of male adolescents in a juvenile justice treatment institution

The present study examines the reliability and construct validity of the Dutch version of the Psychopathy Check List: Youth Version (PCL:YV) in a sample of male adolescents admitted to a secure juvenile justice treatment institution (N = 98). Hare's four-factor model is used to examine reliability and validity of the separate dimensions of psychopathy. Interrater reliabilities are good to excellent for the PCL:YV total score and most factor scores, except for the affective factor. Several suggestions are offered for optimizing reliability of this factor. Finally, meaningful associations between PCL:YV scores and scores on the Minnesota Multiphasic Personality Inventory-Adolescent and the Interpersonal Checklist-Revised support the construct validity of the PCL:YV total score as well as the four factors in the Dutch contex