354 research outputs found
Remyelination Failure in Multiple Sclerosis and Vulnerability of Oligodendrocytes to Repeated Insults
Putative effects of neurofilaments released during multiple sclerosis
Lesions in multiple sclerosis (MS) are characterized by inflammation, oligodendrocytes (OL) death and demyelination as well as axon lesions. The remyelination failure associates with persistent axonal alterations [1, 2], and this results in permanent disability for patients. These axon lesions can occur early in the course of the disease [3], but their origin is equivocal. They could result directly from inflammation, or they could be secondary to prolonged demyelination [4]. It is striking that experimentally remyelination alleviates them [5, 6]. [...
Les protéines axonales accroissent la survie des oligodendrocytes après agression toxique in vitro
Analyse ultrastructurale du cytosquelette axonal dans les polyradiculonévrites inflammatoires démyélinisantes chroniques (PIDC)
Putative role of neurofilament-tubulin binding site in axon-glia interactios during remyelination
Restricted oligodendrocyte plasticity and persistent demyelination in Multiple Sclerosis (MS)
Oligodendrocyte Plasticity: Role of Growth Factors and Axon Proteins during Demyelination and Remyelination
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