Modeling and Validation of Local Electrowinning Electrode Current Density Using Two Phase Flow and Nernst-Planck Equations

In this work we demonstrate the validity of a multi-physics model using COMSOL to predict the local current density distribution at the cathode of a copper electrowinning test cell. Important developments utilizing Euler-Euler bubbly flow with coupled Nernst-Planck transport equations allow additional insights into deposit characteristics and topographies

Concept Design of Cryogenic Propellant Storage and Transfer for Space Exploration

NASA is in the planning and investigation process of developing innovative paths for human space exploration that strengthen the capability to extend human and robotic presence beyond low Earth orbit and throughout the solar system. NASA is establishing the foundations to enable humans to safely reach multiple potential destinations, including the Moon, asteroids, Lagrange points, and Mars and its environs through technology and capability development. To achieve access to these destinations within a reasonable flight time will require the use of high performance cryogenic propulsion systems. Therefore NASA is examining mission concepts for a Cryogenic Propellant Storage and Transfer (CPST) Flight Demonstration which will test and validate key capabilities and technologies required for future exploration elements such as large cryogenic propulsion stages and propellant depots. The CPST project will perform key ground testing in fiscal year 2012 and execute project formulation and implementation leading to a flight demonstration in 2017

Giant Shapiro Resonances in a Flux Driven Josephson Junction Necklace

We present a detailed study of the dynamic response of a ring of $N$ equally spaced Josephson junctions to a time-periodic external flux, including screening current effects. The dynamics are described by the resistively shunted Josephson junction model, appropriate for proximity effect junctions, and we include Faraday's law for the flux. We find that the time-averaged $I-V$ characteristics show novel {\em subharmonic giant Shapiro voltage resonances}, which strongly depend on having phase slips or not, on $N$, on the inductance and on the external drive frequency. We include an estimate of the possible experimental parameters needed to observe these quantized voltage spikes.Comment: 8 pages RevTeX, 3 figures available upon reques

Liquid Oxygen/Liquid Methane Propulsion and Cryogenic Advanced Development

Exploration Systems Architecture Study conducted by NASA in 2005 identified the liquid oxygen (LOx)/liquid methane (LCH4) propellant combination as a prime candidate for the Crew Exploration Vehicle Service Module propulsion and for later use for ascent stage propulsion of the lunar lander. Both the Crew Exploration Vehicle and Lunar Lander were part the Constellation architecture, which had the objective to provide global sustained lunar human exploration capability. From late 2005 through the end of 2010, NASA and industry matured advanced development designs for many components that could be employed in relatively high thrust, high delta velocity, pressure fed propulsion systems for these two applications. The major investments were in main engines, reaction control engines, and the devices needed for cryogenic fluid management such as screens, propellant management devices, thermodynamic vents, and mass gauges. Engine and thruster developments also included advanced high reliability low mass igniters. Extensive tests were successfully conducted for all of these elements. For the thrusters and engines, testing included sea level and altitude conditions. This advanced development provides a mature technology base for future liquid oxygen/liquid methane pressure fed space propulsion systems. This paper documents the design and test efforts along with resulting hardware and test results

Development and validation of a risk score for chronic kidney disease in HIV infection using prospective cohort data from the D:A:D study.

Chronic kidney disease (CKD) is a major health issue for HIV-positive individuals, associated with increased morbidity and mortality. Development and implementation of a risk score model for CKD would allow comparison of the risks and benefits of adding potentially nephrotoxic antiretrovirals to a treatment regimen and would identify those at greatest risk of CKD. The aims of this study were to develop a simple, externally validated, and widely applicable long-term risk score model for CKD in HIV-positive individuals that can guide decision making in clinical practice

Flux Pinning and Phase Transitions in Model High-Temperature Superconductors with Columnar Defects

We calculate the degree of flux pinning by defects in model high-temperature superconductors (HTSC's). The HTSC is modeled as a three-dimensional network of resistively-shunted Josephson junctions in an external magnetic field, corresponding to a HTSC in the extreme Type-II limit. Disorder is introduced either by randomizing the coupling between grains (Model A disorder) or by removing grains (Model B disorder). Three types of defects are considered: point disorder, random line disorder, and periodic line disorder; but the emphasis is on random line disorder. Static and dynamic properties of the models are determined by Monte Carlo simulations and by solution of the analogous coupled overdamped Josephson equations in the presence of thermal noise. Random line defects considerably raise the superconducting transition temperature T$_c(B)$, and increase the apparent critical current density J$_c(B,T)$, in comparison to the defect-free crystal. They are more effective in these respects than a comparable volume density of point defects, in agreement with the experiments of Civale {\it et al}. Periodic line defects commensurate with the flux lattice are found to raise T$_c(B)$ even more than do random line defects. Random line defects are most effective when their density approximately equals the flux density. Near T$_c(B)$, our static and dynamic results appear consistent with the anisotropic Bose glass scaling hypotheses of Nelson and Vinokur, but with possibly different critical indices:Comment: 10 pages, LaTeX(REVTeX v3.0, twocolumn), 11 figures (not included

Evaluation of robustly optimised intensity modulated proton therapy for nasopharyngeal carcinoma

BACKGROUND AND PURPOSE: To evaluate the dosimetric changes occurring over the treatment course for nasopharyngeal carcinoma (NPC) patients treated with robustly optimised intensity modulated proton therapy (IMPT). MATERIALS AND METHODS: 25 NPC patients were treated to two dose levels (CTV1: 70Gy, CTV2: 54.25Gy) with robustly optimised IMPT plans. Robustness evaluation was performed over 28 error scenarios using voxel-wise minimum distributions to assess target coverage and voxel-wise maximum distributions to assess possible hotspots and critical organ doses. Daily CBCT was used for positioning and weekly repeat CTs (rCT) were taken, on which the plan dose was recalculated and robustly evaluated. Deformable image registration was used to warp and accumulate the nominal, voxel-wise minimum and maximum rCT dose distributions. Changes to target coverage, critical organ and normal tissue dose between the accumulated and planned doses were investigated. RESULTS: 2 patients required a plan adaptation due to reduced target coverage. The D98% in the accumulated voxel-wise minimum distribution was higher than planned for CTV1 in 24/25 patients and for CTV2 in 20/25 patients. Maximum doses to the critical organs remained acceptable in all patients. Other normal tissue doses showed some variation as a result of soft tissue deformations and weight change. Normal tissue complication probabilities for grade ≥2 dysphagia and grade ≥2 xerostomia remained similar to planned values. CONCLUSION: Robustly optimised IMPT plans, in combination with volumetric verification imaging and adaptive planning, provided robust target coverage and acceptable OAR dose variation in our NPC cohort when accumulated over longitudinal data

Einstein equations in the null quasi-spherical gauge

The structure of the full Einstein equations in a coordinate gauge based on expanding null hypersurfaces foliated by metric 2-spheres is explored. The simple form of the resulting equations has many applications -- in the present paper we describe the structure of timelike boundary conditions; the matching problem across null hypersurfaces; and the propagation of gravitational shocks.Comment: 12 pages, LaTeX (revtex, amssymb), revision 18 pages, contains expanded discussion and explanations, updated references, to appear in CQ

Reverberation Mapping Results for Five Seyfert 1 Galaxies

We present the results from a detailed analysis of photometric and spectrophotometric data on five Seyfert 1 galaxies observed as a part of a recent reverberation mapping program. The data were collected at several observatories over a 140-day span beginning in 2010 August and ending in 2011 January. We obtained high sampling-rate light curves for Mrk 335, Mrk 1501, 3C120, Mrk 6, and PG2130+099, from which we have measured the time lag between variations in the 5100 Angstrom continuum and the H-beta broad emission line. We then used these measurements to calculate the mass of the supermassive black hole at the center of each of these galaxies. Our new measurements substantially improve previous measurements of MBH and the size of the broad line-emitting region for four sources and add a measurement for one new object. Our new measurements are consistent with photoionization physics regulating the location of the broad line region in active galactic nuclei.Comment: 45 pages, 5 figures. Accepted for publication in ApJ. For a brief video explaining the key results of this paper, see http://www.youtube.com/user/OSUAstronom

Reverberation Mapping of the Seyfert 1 Galaxy NGC 7469

A large reverberation mapping study of the Seyfert 1 galaxy NGC 7469 has yielded emission-line lags for Hbeta 4861 and He II 4686 and a central black hole mass measurement of about 10 million solar masses, consistent with previous measurements. A very low level of variability during the monitoring campaign precluded meeting our original goal of recovering velocity-delay maps from the data, but with the new Hbeta measurement, NGC 7469 is no longer an outlier in the relationship between the size of the Hbeta-emitting broad-line region and the AGN luminosity. It was necessary to detrend the continuum and Hbeta and He II 4686 line light curves and those from archival UV data for different time-series analysis methods to yield consistent results.Comment: 9 Pages, 7 figures, 6 tables. Accepted for publication in The Astrophysical Journa