4 research outputs found

    Vision-based Deep Learning Model for Guiding Multi-fingered Robotic Grasping

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    Grasping is an area where humans still vastly outperform robots. By leveraging recent advances in deep learning we propose a vision-based model to generate human-inspired sequences of grasping primitives suitable for transfer to multi-fingered robotic hands. The proposed model, inspired by Neural Image Captioning, consists of a convolutional and recurrent part. The convolutional part employs a pre-trained model from ILSVRC-2014 adapted to combine features from multiple points of view of a single object by using a view pooling layer. The extracted features are then used to seed Long Short Term Memory recurrent units and generate sequences of primitives that can be used to guide a sophisticated multi-fingered robotic hand during the approach leading to a grasp

    Whole-Genome Sequencing Reveals That Regulatory and Low Pleiotropy Variants Underlie Local Adaptation to Environmental Variability in Purple Sea Urchins

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    Organisms experience environments that vary across both space and time. Such environmental heterogeneity shapes standing genetic variation and may influence species’ capacity to adapt to rapid environmental change. However, we know little about the kindof genetic variation that is involved in local adaptation to environmental variability. To address this gap, we sequenced the whole genomes of 140 purple sea urchins (Strongylocentrotus purpuratus) from seven populations that vary in their degree of pH variability. Despite no evidence of global population structure, we found a suite of single-nucleotide polymorphisms (SNPs) tightly correlated with local pH variability (outlier SNPs), which were overrepresented in regions putatively involved in gene regulation (long noncoding RNA and enhancers), supporting the idea that variation in regulatory regions is important for local adaptation to variability. In addition, outliers in genes were found to be (i) enriched for biomineralization and ion homeostasis functions related to low pH response, (ii) less central to the protein-protein interaction network, and (iii) underrepresented among genes highly expressed during early development. Taken together, these results suggest that loci that underlie local adaptation to pH variability in purple sea urchins fall in regions with potentially low pleiotropic effects (based on analyses involving regulatory regions, network centrality, and expression time) involved in low pH response (based on functional enrichment)
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