4 research outputs found

    A multiwavelength study of a massive, active galaxy at z similar to 2:coupling the kinematics of the ionized and molecular gas

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    We report a multiwavelength study of the massive ( M-* greater than or similar to 10(11)M(circle dot)), z similar to 2 star-forming galaxy GMASS 0953, which hosts an obscured AGN. We combined near-infrared observations of the GNIRS, SINFONI and KMOS spectrographs to study the kinematics of the [O III] lambda 5007 and H alpha emission lines. Our analysis shows that GMASS 0953 may host an ionized disc extending up to 13 kpc, which rotates at a velocity of V-ion = 203(-20)(+17) km s(-1) at the outermost radius. Evidence of rotation on a smaller scale (R similar to 1 kpc) arises from the CO(J = 6-5) line. The central velocity V-CO = 320(-53)(+92) km s(-1) traced by the molecular gas is higher than V-ion, suggesting that the galaxy harbours a multiphase disc with a rotation curve that peaks in the very central regions. The galaxy appears well located on the z = 0 baryonic Tully-Fisher relation. We also discuss the possibility that the [O III] lambda 5007 and H alpha velocity gradients are due to a galactic-scale wind. Besides, we found evidence of an AGN-driven outflow traced by a broad blueshifted wing affecting the [O III] lambda 5007 line, which presents a velocity offset Delta v = -535 +/- 152 km s(-1) from the systemic velocity. Because of the short depletion time-scale (tau(dep) similar to 10(8) yr) due to gas ejection and gas consumption by star formation activity, GMASS 0953 may likely evolve into a passive galaxy. However, the role of the AGN in depleting the gas reservoir of the galaxy is quite unclear because of the uncertainties affecting the outflow rate

    ALIX Regulates Tumor-Mediated Immunosuppression by Controlling EGFR Activity and PD-L1 Presentation

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    This work was supported by Cancer Research UK (grants C1519/A6906 and C5255/A15935); by the King’s College London-UCL Comprehensive Cancer Imaging Centre (CRUK and EPSRC, grants C1519/A10331 and C1519/A16463), in association with the MRC and DoH (grant C1519/A10331); by the EU FP7 grants IMAGINT (EC grant: 259881); and by KCL Breast Cancer Now Unit funding (for F.F.-B.; grant KCL-Q2-Y5). J.G.C. is a Wellcome Trust Senior Research fellow (206346/Z/17/Z). The purchase of the siRNA library was possible thanks to a generous gift from Ms. Marianne B. Blake, who raised funds during the 2010 London Marathon through Dimbleby Cancer Care

    Dynamic Integrity Constraints Definition and Enforcement in Databases: A Classification Framework

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    A dynamic constraint expresses conditions that involve facts of two or more states of the database. Since the database is expected to satisfy such conditions, a fundamental issue about integrity constraints is their enforcement. Many methods have been developed in this respect. The purpose of this paper is to present a brief survey of methods for dynamic constraint definition and enforcement. Also we classify and compare these methods with respect to several relevant features. Keywords Dynamic integrity constraints, integrity enforcement, survey, classification * Permanent address: Diretoria de Processamento de Dados, Universidade Federal de Uberlândia, Uberlândia, MG, Brazil (E-mail: [email protected]) 1 INTRODUCTION In the field of information systems and databases, the term integrity normally refers to the correctness or validity of the stored data, as defined explicitly by means of integrity rules or integrity constraints (Grefen and Apers, 1993). Integrity is a very impo..
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