Protocollo operativo per la validazione geometrica di immagini satellitari ad alta risoluzione

Nel corso degli ultimi anni, la crescente disponibilità di scene acquisite da satelliti ad alta risoluzione spaziale (come GeoEye-1, WorldView-1 e 2 o Pleiades-1A e 1B) ha aperto nuovi scenari di applicazioni realizzabili a scala medio-piccola, avvicinando così il Telerilevamento alla Fotogrammetria

Protocollo operativo per la validazione geometrica di immagini satellitari ad alta risoluzione

Nel corso degli ultimi anni, la crescente disponibilita\u300 di scene acquisite da satelliti ad alta risoluzione spaziale (come GeoEye-1, WorldView-1 e 2 o Pleiades-1A e 1B) ha aperto nuovi scenari di applicazioni realizzabili a scala medio-piccola, avvicinando cosi\u300 il Telerilevamento alla Fotogrammetria

Colorectal Cancer Stage at Diagnosis Before vs During the COVID-19 Pandemic in Italy

IMPORTANCE Delays in screening programs and the reluctance of patients to seek medical attention because of the outbreak of SARS-CoV-2 could be associated with the risk of more advanced colorectal cancers at diagnosis. OBJECTIVE To evaluate whether the SARS-CoV-2 pandemic was associated with more advanced oncologic stage and change in clinical presentation for patients with colorectal cancer. DESIGN, SETTING, AND PARTICIPANTS This retrospective, multicenter cohort study included all 17 938 adult patients who underwent surgery for colorectal cancer from March 1, 2020, to December 31, 2021 (pandemic period), and from January 1, 2018, to February 29, 2020 (prepandemic period), in 81 participating centers in Italy, including tertiary centers and community hospitals. Follow-up was 30 days from surgery. EXPOSURES Any type of surgical procedure for colorectal cancer, including explorative surgery, palliative procedures, and atypical or segmental resections. MAIN OUTCOMES AND MEASURES The primary outcome was advanced stage of colorectal cancer at diagnosis. Secondary outcomes were distant metastasis, T4 stage, aggressive biology (defined as cancer with at least 1 of the following characteristics: signet ring cells, mucinous tumor, budding, lymphovascular invasion, perineural invasion, and lymphangitis), stenotic lesion, emergency surgery, and palliative surgery. The independent association between the pandemic period and the outcomes was assessed using multivariate random-effects logistic regression, with hospital as the cluster variable. RESULTS A total of 17 938 patients (10 007 men [55.8%]; mean [SD] age, 70.6 [12.2] years) underwent surgery for colorectal cancer: 7796 (43.5%) during the pandemic period and 10 142 (56.5%) during the prepandemic period. Logistic regression indicated that the pandemic period was significantly associated with an increased rate of advanced-stage colorectal cancer (odds ratio [OR], 1.07; 95%CI, 1.01-1.13; P = .03), aggressive biology (OR, 1.32; 95%CI, 1.15-1.53; P < .001), and stenotic lesions (OR, 1.15; 95%CI, 1.01-1.31; P = .03). CONCLUSIONS AND RELEVANCE This cohort study suggests a significant association between the SARS-CoV-2 pandemic and the risk of a more advanced oncologic stage at diagnosis among patients undergoing surgery for colorectal cancer and might indicate a potential reduction of survival for these patients

Near Real-Time Multi-GPU omegaK Algorithm for SAR Processing

This paper presents a Near-Real-Time multi-GPU accelerated solution of the ωk Algorithm for Synthetic Aperture Radar (SAR) data focusing, obtained in Stripmap SAR mode. Starting from an input raw data, the algorithm subdivides it in a grid of a configurable number of bursts along track. A multithreading CPU-side support is made available in order to handle each graphic device in parallel. Then each burst is assigned to a separate GPU and processed including Range Compression, Stolt Mapping via ChirpZ and Azimuth Compression steps. We prove the efficiency of our algorithm by using Sentinel-1 raw data (approx. 3.3 GB) on a commodity graphics card; the single-GPU solution is approximately 4x faster than the industrial multi-core CPU implementation (General ACS SAR Processor, GASP), without significant loss of quality. Using a multi-GPU system, the algorithm is approximately 6x faster with respect to the CPU processor

Near Real-Time Multi-GPU omegaK Algorithm for SAR Processing

This paper presents a Near-Real-Time multi-GPU accelerated solution of the ωk Algorithm for Synthetic Aperture Radar (SAR) data focusing, obtained in Stripmap SAR mode. Starting from an input raw data, the algorithm subdivides it in a grid of a configurable number of bursts along track. A multithreading CPU-side support is made available in order to handle each graphic device in parallel. Then each burst is assigned to a separate GPU and processed including Range Compression, Stolt Mapping via ChirpZ and Azimuth Compression steps. We prove the efficiency of our algorithm by using Sentinel-1 raw data (approx. 3.3 GB) on a commodity graphics card; the single-GPU solution is approximately 4x faster than the industrial multi-core CPU implementation (General ACS SAR Processor, GASP), without significant loss of quality. Using a multi-GPU system, the algorithm is approximately 6x faster with respect to the CPU processor

Heart failure and iron deficiency anemia in Italy: Results from CARMES-1 registry

Aims: To assess the prevalence of anemia and iron deficiency anemia in heart failure (HF) patients, to evaluate the effectiveness of current iron deficiency treatment strategies after discharge, and to analyze hospital readmissions and mortality rates in patients with and without anemia. Patients & methods: A patient registry-based, multicenter, retrospective, observational, cohort study of 418 hospitalized HF patients in Italy, monitored from 1 March 2010 to 30 March 2011. Results: Among patients with HF, 35.9% had anemia at admission; only 51.3% were treated with current iron deficiency treatment strategies during hospitalization and then only 29% of patients who were anemic at discharge were treated with iron at home. After a 4-week follow-up, only 11% of these patients reached the hemoglobin target value (study primary end point). However, current iron deficiency treatment strategies were not significantly associated with reduced risk of rehospitalization, but with a significantly reduced mortality rate after a 6-month follow-up (study secondary end points: 11.7 vs 51.7%; p < 0.0001). Conclusion: In HF patients, there is poor attention paid to anemia, its causes and treatment. Current iron deficiency treatment strategies are mismanaged and CARMES-1 demonstrated that they appear to be insufficient at improving patient outcome in terms of rehospitalization rate reduction, generating high costs, which could be avoided through an optimized treatment strategy. Therefore, more efficacious, efficient and cost-effective treatment strategies are required in Italy for HF patients with iron deficiency anemia to meet this unmet medical need. © 2013 Future Medicine Ltd

Effect of centre volume on pathological outcomes and postoperative complications after surgery for colorectal cancer: results of a multicentre national study

Background: The association between volume, complications and pathological outcomes is still under debate regarding colorectal cancer surgery. The aim of the study was to assess the association between centre volume and severe complications, mortality, less-than-radical oncologic surgery, and indications for neoadjuvant therapy.Methods: Retrospective analysis of 16,883 colorectal cancer cases from 80 centres (2018-2021). Outcomes: 30-day mortality; Clavien-Dindo grade >2 complications; removal of >= 12 lymph nodes; non-radical resection; neoadjuvant therapy. Quartiles of hospital volumes were classified as LOW, MEDIUM, HIGH, and VERY HIGH. Independent predictors, both overall and for rectal cancer, were evaluated using logistic regression including age, gender, AJCC stage and cancer site.Results: LOW-volume centres reported a higher rate of severe postoperative complications (OR 1.50, 95% c.i. 1.15-1.096, P = 0.003). The rate of >= 12 lymph nodes removed in LOW-volume (OR 0.68, 95% c.i. 0.56-0.85, P = 12 lymph nodes removed was lower in LOW-volume than in VERY HIGH-volume centres (OR 0.57, 95% c.i. 0.41-0.80, P = 0.001). A lower rate of neoadjuvant chemoradiation was associated with HIGH (OR 0.66, 95% c.i. 0.56-0.77, P < 0.001), MEDIUM (OR 0.75, 95% c.i. 0.60-0.92, P = 0.006), and LOW (OR 0.70, 95% c.i. 0.52-0.94, P = 0.019) volume centres (vs. VERY HIGH).Conclusion: Colorectal cancer surgery in low-volume centres is at higher risk of suboptimal management, poor postoperative outcomes, and less-than-adequate oncologic resections. Centralisation of rectal cancer cases should be taken into consideration to optimise the outcomes